compared across groups. Additionally, it was tested for an interaction of alpha band power and diagnosis on BOLD signal in a fixed effects model. As a next step, we used BOLD signal changes from within apriori specified regions of the DMN in the regression analysis. Results:Results of the first-level whole-brain analysis showed that occipital alpha band power correlated positively with BOLD signal within regions that are part of the DMN, and negatively with BOLD signal in occipital and frontal regions (p<.001, uncorr.). Notably, there was high inter-individual variability concerning brain regions and correlation strength. The results of the second-level analysis will be presented at the conference. Conclusions:The study provides insight into the correlation of altered spontaneous EEG rhythm and fMRI signal during resting-state in AD patients. First results indicate that occipital alpha band power may be positively correlated with BOLD signal in DMN regions. In addition, this study shows the feasibility of simultaneous EEG-fMRI measurement in AD patients.