The In Vitro and In Vivo Response to MMP-Sensitive Poly(Ethylene Glycol) Hydrogels

[1]  Franck J. Vernerey,et al.  Tuning Reaction and Diffusion Mediated Degradation of Enzyme‐Sensitive Hydrogels , 2016, Advanced healthcare materials.

[2]  D. Bezuidenhout,et al.  Regulation of tissue ingrowth into proteolytically degradable hydrogels. , 2015, Acta biomaterialia.

[3]  Stephanie J Bryant,et al.  Enzymatically degradable poly(ethylene glycol) hydrogels for the 3D culture and release of human embryonic stem cell derived pancreatic precursor cell aggregates. , 2015, Acta biomaterialia.

[4]  S. Gill,et al.  The role of TIMPs in regulation of extracellular matrix proteolysis. , 2015, Matrix biology : journal of the International Society for Matrix Biology.

[5]  Kristi S Anseth,et al.  Development of a Cellularly Degradable PEG Hydrogel to Promote Articular Cartilage Extracellular Matrix Deposition , 2015, Advanced healthcare materials.

[6]  C. S. Ki,et al.  Thiol-norbornene photo-click hydrogels for tissue engineering applications. , 2015, Journal of applied polymer science.

[7]  Anna K. Blakney,et al.  Linking the foreign body response and protein adsorption to PEG-based hydrogels using proteomics. , 2015, Biomaterials.

[8]  Jason A Burdick,et al.  Modulating hydrogel crosslink density and degradation to control bone morphogenetic protein delivery and in vivo bone formation. , 2014, Journal of controlled release : official journal of the Controlled Release Society.

[9]  K. Healy,et al.  Controlling Osteogenic Stem Cell Differentiation via Soft Bioinspired Hydrogels , 2014, PloS one.

[10]  M. Gillings,et al.  Fungal Community Structure in Disease Suppressive Soils Assessed by 28S LSU Gene Sequencing , 2014, PloS one.

[11]  W. Parks,et al.  Diverse functions of matrix metalloproteinases during fibrosis , 2014, Disease Models & Mechanisms.

[12]  Matthew T. Basel,et al.  Nanoplatforms for highly sensitive fluorescence detection of cancer-related proteases , 2014, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[13]  Justine J. Roberts,et al.  Comparison of photopolymerizable thiol-ene PEG and acrylate-based PEG hydrogels for cartilage development. , 2013, Biomaterials.

[14]  A. Ranga,et al.  Artificial three-dimensional niches deconstruct pancreas development in vitro , 2013, Development.

[15]  D. Bezuidenhout,et al.  Cell specific ingrowth hydrogels. , 2013, Biomaterials.

[16]  Chien-Chi Lin,et al.  The influence of matrix degradation and functionality on cell survival and morphogenesis in PEG-based hydrogels. , 2013, Macromolecular bioscience.

[17]  H. Ahsan,et al.  Alpha‐2‐macroglobulin: A physiological guardian , 2013, Journal of cellular physiology.

[18]  Mohammad Wahid Ansari,et al.  The legal status of in vitro embryos , 2014 .

[19]  S. Sokic.  Enhanced degradation and peptide specificity of MMP-sensitive scaffolds for neovascularization of engineered tissues , 2013 .

[20]  Christopher E. Nelson,et al.  Matrix Metalloproteinase Responsive, Proximity‐Activated Polymeric Nanoparticles for siRNA Delivery , 2013, Advanced functional materials.

[21]  Chien-Liang Wu,et al.  Circulating Matrix Metalloproteinase-2 and -9 Enzyme Activities in the Children with Ventricular Septal Defect , 2013, International journal of biological sciences.

[22]  Kristi S. Anseth,et al.  Synthetic hydrogel platform for three-dimensional culture of embryonic stem cell-derived motor neurons. , 2013, Biomaterials science.

[23]  Eric M. Brey,et al.  MMP-Sensitive PEG Diacrylate Hydrogels with Spatial Variations in Matrix Properties Stimulate Directional Vascular Sprout Formation , 2013, PloS one.

[24]  Wei-Chun Huang,et al.  Classical Macrophage Activation Up-Regulates Several Matrix Metalloproteinases through Mitogen Activated Protein Kinases and Nuclear Factor-κB , 2012, PloS one.

[25]  Stephanie J Bryant,et al.  The effects of substrate stiffness on the in vitro activation of macrophages and in vivo host response to poly(ethylene glycol)-based hydrogels. , 2012, Journal of biomedical materials research. Part A.

[26]  Stephanie J Bryant,et al.  Temporal progression of the host response to implanted poly(ethylene glycol)-based hydrogels. , 2011, Journal of biomedical materials research. Part A.

[27]  J. West,et al.  A bioresponsive hydrogel tuned to chondrogenesis of human mesenchymal stem cells , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[28]  J. Hubbell,et al.  Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2. , 2010, Biomaterials.

[29]  Mayumi Mochizuki,et al.  Engineering Integrin Signaling for Promoting Embryonic Stem Cell Self-renewal in a Precisely Defined Niche , 2022 .

[30]  So-Yeon Kim,et al.  Role of NADPH oxidase‐2 in lipopolysaccharide‐induced matrix metalloproteinase expression and cell migration , 2010, Immunology and cell biology.

[31]  Kristi S. Anseth,et al.  A Versatile Synthetic Extracellular Matrix Mimic via Thiol‐Norbornene Photopolymerization , 2009, Advanced materials.

[32]  R. Koren,et al.  Upregulation of MMP‐9 production by TNFα in keratinocytes and its attenuation by vitamin D , 2009, Journal of cellular physiology.

[33]  Stephanie J Bryant,et al.  Characterization of the in vitro macrophage response and in vivo host response to poly(ethylene glycol)-based hydrogels. , 2009, Journal of biomedical materials research. Part A.

[34]  B. Koo,et al.  Regulatory Mechanism of Matrix Metalloprotease-2 Enzymatic Activity by Factor Xa and Thrombin* , 2009, The Journal of Biological Chemistry.

[35]  T. Kyriakides,et al.  Matrix metalloproteinase-9 deficiency leads to prolonged foreign body response in the brain associated with increased IL-1beta levels and leakage of the blood-brain barrier. , 2009, Matrix biology : journal of the International Society for Matrix Biology.

[36]  A. Newby.  Metalloproteinase Expression in Monocytes and Macrophages and its Relationship to Atherosclerotic Plaque Instability , 2008, Arteriosclerosis, thrombosis, and vascular biology.

[37]  S. Bryant,et al.  Cell encapsulation in biodegradable hydrogels for tissue engineering applications. , 2008, Tissue engineering. Part B, Reviews.

[38]  James M. Anderson,et al.  Foreign body reaction to biomaterials. , 2008, Seminars in immunology.

[39]  Steven M. Jay,et al.  Foreign body giant cell formation is preceded by lamellipodia formation and can be attenuated by inhibition of Rac1 activation. , 2007, The American journal of pathology.

[40]  P. Neth,et al.  Scientific category: Stem cells in hematology MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines , 2006 .

[41]  E. Jabbari,et al.  Material properties and cytocompatibility of injectable MMP degradable poly(lactide ethylene oxide fumarate) hydrogel as a carrier for marrow stromal cells. , 2007, Biomacromolecules.

[42]  Younghee Lee,et al.  NF-kappaB-dependent regulation of matrix metalloproteinase-9 gene expression by lipopolysaccharide in a macrophage cell line RAW 264.7. , 2007, Journal of biochemistry and molecular biology.

[43]  K. Healy,et al.  Biomimetic artificial ECMs stimulate bone regeneration. , 2006, Journal of biomedical materials research. Part A.

[44]  M. Harmsen,et al.  The correlation between difference in foreign body reaction between implant locations and cytokine and MMP expression. , 2006, Biomaterials.

[45]  J. Heemskerk,et al.  Shedding of procoagulant microparticles from unstimulated platelets by integrin‐mediated destabilization of actin cytoskeleton , 2006, FEBS letters.

[46]  Buddy D Ratner,et al.  Biomaterials: where we have been and where we are going. , 2004, Annual review of biomedical engineering.

[47]  L. Yahia,et al.  Metalloproteinase and cytokine production by THP-1 macrophages following exposure to chitosan-DNA nanoparticles. , 2004, Biomaterials.

[48]  E. Butcher,et al.  Chemokines in the systemic organization of immunity , 2003, Immunological reviews.

[49]  A. Newby,et al.  Statins Inhibit Secretion of Metalloproteinases-1, -2, -3, and -9 From Vascular Smooth Muscle Cells and Macrophages , 2003, Arteriosclerosis, thrombosis, and vascular biology.

[50]  Ralph Müller,et al.  Repair of bone defects using synthetic mimetics of collagenous extracellular matrices , 2003, Nature Biotechnology.

[51]  A. Metters,et al.  Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: Engineering cell-invasion characteristics , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[52]  G. Hitman,et al.  Circulating MMP9, vitamin D and variation in the TIMP-1 response with VDR genotype: mechanisms for inflammatory damage in chronic disorders? , 2002, QJM : monthly journal of the Association of Physicians.

[53]  J. Hubbell,et al.  Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids. , 2001, Bioconjugate chemistry.

[54]  G. Bancroft,et al.  Production of Matrix Metalloproteinases in Response to Mycobacterial Infection , 2001, Infection and Immunity.

[55]  James M. Anderson,et al.  Biological Responses to Materials , 2001 .

[56]  L. Cantley,et al.  Determination of protease cleavage site motifs using mixture-based oriented peptide libraries , 2001, Nature Biotechnology.

[57]  S J Bryant,et al.  Cytocompatibility of UV and visible light photoinitiating systems on cultured NIH/3T3 fibroblasts in vitro , 2000, Journal of biomaterials science. Polymer edition.

[58]  A. Shinagawa,et al.  Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2). , 1994, Journal of cell science.

[59]  K. Iwata,et al.  Growth‐promoting activity of tissue inhibitor of metalloproteinases‐1 (TIMP‐1) for a wide range of cells A possible new growth factor in serum , 1992, FEBS letters.

[60]  S. Bryant,et al.  Understanding the host response to cell-laden poly(ethylene glycol)-based hydrogels. , 2013, Biomaterials.

[61]  Q. Gao,et al.  Macrophage matrix metalloproteinase-2/-9 gene and protein expression following adhesion to ECM-derived multifunctional matrices via integrin complexation. , 2007, Biomaterials.

[62]  NobuoHashimoto,et al.  Macrophage-Derived Matrix Metalloproteinase-2 and -9 Promote the Progression of Cerebral Aneurysms in Rats , 2007 .

[63]  G. Fields,et al.  Human matrix metalloproteinase specificity studies using collagen sequence-based synthetic peptides. , 1996, Biopolymers.