Phenotypic Differences in Primary Murine Microglia Treated with NOD1, NOD2, and NOD1/2 Agonists

[1]  A. Heiligenhaus,et al.  Loss of IL-10 Promotes Differentiation of Microglia to a M1 Phenotype , 2019, Front. Cell. Neurosci..

[2]  D. Brites,et al.  Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation , 2017, Front. Aging Neurosci..

[3]  S. Rivest,et al.  Triggering of NOD2 Receptor Converts Inflammatory Ly6Chigh into Ly6Clow Monocytes with Patrolling Properties. , 2017, Cell reports.

[4]  T. Langmann,et al.  Comprehensive analysis of mouse retinal mononuclear phagocytes , 2017, Nature Protocols.

[5]  H. Kettenmann,et al.  Microglia in Physiology and Disease. , 2017, Annual review of physiology.

[6]  A. Mildner,et al.  P2Y12 receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases , 2017, Glia.

[7]  Minshu Li,et al.  Depletion of microglia exacerbates postischemic inflammation and brain injury , 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[8]  M. Olsen,et al.  Novel Applications of Magnetic Cell Sorting to Analyze Cell-Type Specific Gene and Protein Expression in the Central Nervous System , 2016, PloS one.

[9]  Pablo de Gracia,et al.  Automatic Counting of Microglial Cells in Healthy and Glaucomatous Mouse Retinas , 2015, PloS one.

[10]  J. Forrester,et al.  Retinal Microglial Activation Following Topical Application of Intracellular Toll-Like Receptor Ligands. , 2015, Investigative ophthalmology & visual science.

[11]  F. Ginhoux,et al.  Origin of microglia: current concepts and past controversies. , 2015, Cold Spring Harbor perspectives in biology.

[12]  H. Neumann,et al.  Activated microglia/macrophage whey acidic protein (AMWAP) inhibits NFκB signaling and induces a neuroprotective phenotype in microglia , 2015, Journal of Neuroinflammation.

[13]  C. Laver,et al.  Enhanced functional integration of human photoreceptor precursors into human and rodent retina in an ex vivo retinal explant model system. , 2015, Tissue engineering. Part A.

[14]  J. Bajramovic,et al.  Inflammasome-Induced IL-1β Secretion in Microglia Is Characterized by Delayed Kinetics and Is Only Partially Dependent on Inflammatory Caspases , 2015, The Journal of Neuroscience.

[15]  Jeffery Grigsby,et al.  The Role of Microglia in Diabetic Retinopathy , 2014, Journal of ophthalmology.

[16]  Adelaide Fernandes,et al.  Microglia change from a reactive to an age-like phenotype with the time in culture , 2014, Front. Cell. Neurosci..

[17]  Mei Chen,et al.  Culture and Characterization of Microglia from the Adult Murine Retina , 2014, TheScientificWorldJournal.

[18]  J. Champagnat,et al.  Activation of microglia and astrocytes in the nucleus tractus solitarius during ventilatory acclimatization to 10% hypoxia in unanesthetized mice , 2014, Journal of neuroscience research.

[19]  D. Philpott,et al.  NOD proteins: regulators of inflammation in health and disease , 2013, Nature Reviews Immunology.

[20]  S. Gygi,et al.  Identification of a Unique TGF-β Dependent Molecular and Functional Signature in Microglia , 2013, Nature Neuroscience.

[21]  M. Horiuchi,et al.  Absence of CD14 Delays Progression of Prion Diseases Accompanied by Increased Microglial Activation , 2013, Journal of Virology.

[22]  G. Lutty,et al.  VEGF Receptor Blockade Markedly Reduces Retinal Microglia/Macrophage Infiltration into Laser-Induced CNV , 2013, PloS one.

[23]  P. Gressens,et al.  Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro , 2013, Brain, Behavior, and Immunity.

[24]  F. Rosenbauer,et al.  Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways , 2013, Nature Neuroscience.

[25]  F. Roudot-thoraval,et al.  Hyperreflective Dots: A New Spectral-Domain Optical Coherence Tomography Entity for Follow-Up and Prognosis in Exudative Age-Related Macular Degeneration , 2012, Ophthalmologica.

[26]  D. Fitzgerald,et al.  Para‐inflammation‐mediated retinal recruitment of bone marrow‐derived myeloid cells following whole‐body irradiation is CCL2 dependent , 2012, Glia.

[27]  J. Wilschut,et al.  Induction of mucosal and systemic immunity against respiratory syncytial virus by inactivated virus supplemented with TLR9 and NOD2 ligands. , 2012, Vaccine.

[28]  R. Ransohoff,et al.  The Fractalkine Receptor but Not CCR2 Is Present on Microglia from Embryonic Development throughout Adulthood , 2012, The Journal of Immunology.

[29]  O. Witte,et al.  In Situ Dividing and Phagocytosing Retinal Microglia Express Nestin, Vimentin, and NG2 In Vivo , 2011, PloS one.

[30]  E. E. Vance,et al.  NOD2 deficiency results in increased susceptibility to peptidoglycan-induced uveitis in mice. , 2011, Investigative ophthalmology & visual science.

[31]  C. Grangette,et al.  Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide , 2011, Gut.

[32]  H. Kettenmann,et al.  Physiology of microglia. , 2011, Physiological reviews.

[33]  F. Ginhoux,et al.  Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages , 2010, Science.

[34]  R. Coffman,et al.  Vaccine adjuvants: putting innate immunity to work. , 2010, Immunity.

[35]  T. Langmann,et al.  The Novel Activated Microglia/Macrophage WAP Domain Protein, AMWAP, Acts as a Counter-Regulator of Proinflammatory Response , 2010, The Journal of Immunology.

[36]  I. Marriott,et al.  NOD2 mediates inflammatory responses of primary murine glia to Streptococcus pneumoniae , 2010, Glia.

[37]  H. Rosenzweig,et al.  Nucleotide oligomerization domain-2 (NOD2)-induced uveitis: dependence on IFN-gamma. , 2009, Investigative ophthalmology & visual science.

[38]  V. Perry,et al.  Microglial physiology: unique stimuli, specialized responses. , 2009, Annual review of immunology.

[39]  K. Lambertsen,et al.  Journal of Neuroinflammation Interleukin-1beta and Tumor Necrosis Factor-alpha Are Expressed by Different Subsets of Microglia and Macrophages after Ischemic Stroke in Mice , 2008 .

[40]  Wai T Wong,et al.  Ex vivo dynamic imaging of retinal microglia using time-lapse confocal microscopy. , 2008, Investigative ophthalmology & visual science.

[41]  R. J. Ross,et al.  Immunological protein expression profile in Ccl2/Cx3cr1 deficient mice with lesions similar to age-related macular degeneration. , 2008, Experimental eye research.

[42]  K. Todd,et al.  Differential regulation of trophic and proinflammatory microglial effectors is dependent on severity of neuronal injury , 2008, Glia.

[43]  H. Kettenmann,et al.  Microglia: active sensor and versatile effector cells in the normal and pathologic brain , 2007, Nature Neuroscience.

[44]  A. Heiligenhaus,et al.  On the influence of neutrophils in corneas with necrotizing HSV-1 keratitis following amniotic membrane transplantation. , 2007, Experimental eye research.

[45]  S. Maier,et al.  Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses , 2007, Brain, Behavior, and Immunity.

[46]  R. Ransohoff,et al.  Isolation of murine microglial cells for RNA analysis or flow cytometry , 2006, Nature Protocols.

[47]  I. Marriott,et al.  Characterization of nucleotide-binding oligomerization domain (NOD) protein expression in primary murine microglia , 2006, Journal of Neuroimmunology.

[48]  D. Morgan,et al.  Diverse microglial responses after intrahippocampal administration of lipopolysaccharide , 2006, Glia.

[49]  T. Elsasser,et al.  Interleukin-1 and tumor necrosis factor-mediation of endotoxin action on growth hormone , 2005 .

[50]  K. Suk,et al.  TLR4, but Not TLR2, Signals Autoregulatory Apoptosis of Cultured Microglia: A Critical Role of IFN-β as a Decision Maker 1 , 2005, The Journal of Immunology.

[51]  M. Chamaillard,et al.  Nods, Nalps and Naip: intracellular regulators of bacterial‐induced inflammation , 2003, Cellular microbiology.

[52]  W. A. A. Glance.  Diverse , 2002, Encyclopedia of the UN Sustainable Development Goals.

[53]  S. Fedoroff,et al.  Effect of bacterial wall lipopolysaccharide (LPS) on morphology, motility, and cytoskeletal organization of microglia in cultures , 1995, Journal of neuroscience research.

[54]  A. Ben-nun,et al.  Protection against autoimmune disease by bacterial agents. II. PPD and pertussis toxin as proteins active in protecting mice against experimental autoimmune encephalomyelitis , 1993, European journal of immunology.

[55]  I. Azuma,et al.  Stimulation of nonspecific resistance to infection induced by muramyl dipeptide analogs substituted in the gamma-carboxyl group and evaluation of N alpha-muramyl dipeptide-N epsilon-stearoyllysine , 1983, Infection and immunity.

[56]  I. Azuma,et al.  Stimulation of Nonspecific Host Resistance to Infection Induced by Muramyldipeptides , 1981, Microbiology and immunology.

[57]  E. Lederer,et al.  Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives. , 1974, Biochemical and biophysical research communications.

[58]  M. Graeber,et al.  Microglia: biology and pathology , 2009, Acta Neuropathologica.

[59]  S. Ito,et al.  Pathogenic role of retinal microglia in experimental uveoretinitis. , 2003, Investigative ophthalmology & visual science.

[60]  T Nagatake,et al.  Streptococcus pneumoniae , 2020, Methods in Molecular Biology.