A phase I/IIa clinical trial of third-generation autologous chondrocyte implantation (IK-01) for focal cartilage injury of the knee

[1]  P. Niemeyer,et al.  Matrix-Associated Chondrocyte Implantation Is Associated With Fewer Reoperations Than Microfracture: Results of a Population-Representative, Matched-Pair Claims Data Analysis for Cartilage Defects of the Knee , 2019, Orthopaedic journal of sports medicine.

[2]  D. Flanigan,et al.  Failures, Reoperations, and Improvement in Knee Symptoms Following Matrix-Assisted Autologous Chondrocyte Transplantation: A Meta-Analysis of Prospective Comparative Trials , 2019, Cartilage.

[3]  P. Niemeyer,et al.  Long-Term Clinical and MRI Results of Matrix-Assisted Autologous Chondrocyte Implantation for Articular Cartilage Defects of the Knee , 2019, Cartilage.

[4]  E. McCarty,et al.  Matrix-Assisted Autologous Chondrocyte Transplantation in the Knee: A Systematic Review of Mid- to Long-Term Clinical Outcomes , 2017, Orthopaedic journal of sports medicine.

[5]  J. Ebert,et al.  A Prospective Clinical and Radiological Evaluation at 5 Years After Arthroscopic Matrix-Induced Autologous Chondrocyte Implantation , 2017, The American journal of sports medicine.

[6]  B. Wondrasch,et al.  Clinical and Radiological Long-term Outcomes After Matrix-Induced Autologous Chondrocyte Transplantation , 2014, The American journal of sports medicine.

[7]  N. Caplan,et al.  Two- to 9-Year Outcome After Autologous Chondrocyte Transplantation of the Knee , 2014 .

[8]  J. Hui,et al.  Evidence-based status of second- and third-generation autologous chondrocyte implantation over first generation: a systematic review of level I and II studies. , 2013, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[9]  Christian Krettek,et al.  CaReS® (MACT) versus microfracture in treating symptomatic patellofemoral cartilage defects: a retrospective matched-pair analysis , 2013, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

[10]  Maximilian Rudert,et al.  A Prospective Multicenter Study on the Outcome of Type I Collagen Hydrogel–Based Autologous Chondrocyte Implantation (CaReS) for the Repair of Articular Cartilage Defects in the Knee , 2011, The American journal of sports medicine.

[11]  S. Marlovits,et al.  Gene expression and cell differentiation in matrix-associated chondrocyte transplantation grafts: a comparative study. , 2011, Osteoarthritis and cartilage.

[12]  S. Marlovits,et al.  Evaluation of Cartilage Repair Tissue after Matrix-Associated Autologous Chondrocyte Transplantation Using a Hyaluronic-Based or a Collagen-Based Scaffold with Morphological MOCART Scoring and Biochemical T2 Mapping , 2010, The American journal of sports medicine.

[13]  W. Richter,et al.  Autologous Chondrocyte Implantation Using the Original Periosteum-Cover Technique versus Matrix-Associated Autologous Chondrocyte Implantation , 2010, The American journal of sports medicine.

[14]  N. Iwasaki,et al.  Atelocollagen-associated autologous chondrocyte implantation for the repair of chondral defects of the knee: a prospective multicenter clinical trial in Japan , 2009, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

[15]  M. Steinwachs New technique for cell-seeded collagen-matrix-supported autologous chondrocyte transplantation. , 2009, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[16]  B. Schmidt-Rohlfing,et al.  A Novel Rat Tail Collagen Type-I Gel for the Cultivation of Human Articular Chondrocytes in Low Cell Density , 2007 .

[17]  T. Ackland,et al.  MRI and clinical evaluation of collagen-covered autologous chondrocyte implantation (CACI) at two years. , 2007, The Knee.

[18]  B. Schmidt-Rohlfing,et al.  A novel rat tail collagen type-I gel for the cultivation of human articular chondrocytes in low cell density. , 2007, The International journal of artificial organs.

[19]  Peter Behrens,et al.  Matrix-associated autologous chondrocyte transplantation/implantation (MACT/MACI)--5-year follow-up. , 2006, The Knee.

[20]  Eda T Bloom,et al.  Autologous cultured chondrocytes: adverse events reported to the United States Food and Drug Administration. , 2006, The Journal of bone and joint surgery. American volume.

[21]  J A Skinner,et al.  Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: a prospective, randomised study. , 2005, The Journal of bone and joint surgery. British volume.

[22]  G. Bentley,et al.  Autologous chondrocyte implantation at the knee using a bilayer collagen membrane with bone graft. A preliminary report. , 2005, The Journal of bone and joint surgery. British volume.

[23]  S. Cannon,et al.  The use of chondrogide membrane in autologous chondrocyte implantation. , 2004, The Knee.

[24]  T. Briggs,et al.  Histological evaluation of chondral defects after autologous chondrocyte implantation of the knee. , 2003, The Journal of bone and joint surgery. British volume.

[25]  M. Brittberg,et al.  Evaluation of Cartilage Injuries and Repair , 2003, The Journal of bone and joint surgery. American volume.

[26]  K. Kawasaki,et al.  Transplantation of cartilage-like tissue made by tissue engineering in the treatment of cartilage defects of the knee. , 2002, The Journal of bone and joint surgery. British volume.

[27]  J. Richmond,et al.  Development and Validation of the International Knee Documentation Committee Subjective Knee Form * , 2001, The American journal of sports medicine.

[28]  M. Brittberg,et al.  Two- to 9-Year Outcome After Autologous Chondrocyte Transplantation of the Knee , 2000, Clinical orthopaedics and related research.

[29]  C. Ohlsson,et al.  Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. , 1994, The New England journal of medicine.

[30]  M. Colville,et al.  Osteochondritis Dissecans of the Talus and Knee: Prospective Comparison of MR and Arthroscopic Classifications , 1990, Journal of computer assisted tomography.

[31]  J. Lysholm,et al.  Evaluation of knee ligament surgery results with special emphasis on use of a scoring scale , 1982, The American journal of sports medicine.

[32]  R. Aitken A Growing Edge of Measurement of Feelings [Abridged] , 1969 .

[33]  R. E. Outerbridge The etiology of chondromalacia patellae. , 1961, The Journal of bone and joint surgery. British volume.