Induction of cyclo‐oxygenase‐2 by cytokines in human cultured airway smooth muscle cells: novel inflammatory role of this cell type

[1]  I. Adcock,et al.  Cytokine induction of cytosolic phospholipase A2 and cyclooxygenase-2 mRNA is suppressed by glucocorticoids in human epithelial cells. , 1996, Life sciences.

[2]  B. Kennedy,et al.  Secretory non-pancreatic phospholipase A2 and cyclooxygenase-2 expression by tracheobronchial smooth muscle cells. , 1996, European journal of biochemistry.

[3]  U. Förstermann,et al.  Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-kappa B. , 1996, Molecular pharmacology.

[4]  J. Mitchell,et al.  Cyclooxygenase-2: regulation and relevance in inflammation. , 1995, Biochemical pharmacology.

[5]  S. Dahlén,et al.  Leukotrienes as mediators of airway obstruction and inflammation in asthma , 1995, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[6]  S. Boyce,et al.  Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach. , 1995, The Journal of pharmacology and experimental therapeutics.

[7]  P. Barnes,et al.  Cytokines as mediators of chronic asthma. , 1994, American journal of respiratory and critical care medicine.

[8]  J. Vane,et al.  Induction of cyclo‐oxygenase‐2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone , 1994, British journal of pharmacology.

[9]  A. Ristimäki,et al.  Structure of the human cyclo-oxygenase-2 gene. , 1994, The Biochemical journal.

[10]  R. Flower,et al.  Dexamethasone suppression of IL-1 beta-induced cyclooxygenase 2 expression is not mediated by lipocortin-1 in A549 cells. , 1994, Biochemical and biophysical research communications.

[11]  I. Pavord,et al.  Production of PGE2 by bovine cultured airway smooth muscle cells and its inhibition by cyclo‐oxygenase inhibitors , 1994, British journal of pharmacology.

[12]  J. Vane,et al.  Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[13]  G. Hunninghake,et al.  Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes. , 1994, The Journal of clinical investigation.

[14]  C. Thiemermann,et al.  Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[15]  I. Pavord,et al.  Effect of inhaled prostaglandin E2 on allergen-induced asthma. , 1993, The American review of respiratory disease.

[16]  G. Davis,et al.  Interleukin-1 differentially modulates chondrocyte expression of cyclooxygenase-2 and phospholipase A2. , 1993, Experimental cell research.

[17]  S. Hart,et al.  Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. , 1992, The Journal of biological chemistry.

[18]  P. Barnes,et al.  Quantifying proliferation of cultured human and rabbit airway smooth muscle cells in response to serum and platelet-derived growth factor. , 1992, American journal of respiratory cell and molecular biology.

[19]  M. Grunstein,et al.  Role and mechanism of thromboxane-induced proliferation of cultured airway smooth muscle cells. , 1992, The American journal of physiology.

[20]  C. McCall,et al.  Lipopolysaccharide induces prostaglandin H synthase-2 in alveolar macrophages. , 1992, Biochemical and biophysical research communications.

[21]  I. Pavord,et al.  Effect of inhaled prostaglandin E2 on bronchial reactivity to sodium metabisulphite and methacholine in patients with asthma. , 1991, Thorax.

[22]  R. Erikson,et al.  Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[23]  T. Hla,et al.  Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells. , 1990, The Journal of biological chemistry.

[24]  C. van Breemen,et al.  Human airway smooth muscle in culture. , 1988, Tissue & cell.

[25]  P. Chomczyński,et al.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.

[26]  M. Fujimura,et al.  Effects of a thromboxane synthetase inhibitor (OKY-046) and a lipoxygenase inhibitor (AA-861) on bronchial responsiveness to acetylcholine in asthmatic subjects. , 1986, Thorax.

[27]  K. Chung,et al.  Inhibition of antigen-induced airway hyperresponsiveness by a thromboxane synthetase inhibitor (OKY-046) in allergic dogs. , 1986, The American review of respiratory disease.

[28]  P. O'Byrne,et al.  Significance of thromboxane generation in ozone-induced airway hyperresponsiveness in dogs. , 1985, Journal of applied physiology.

[29]  J. Simon.  A radioimmunoassay for 6-keto- prostaglandin F1α , 1978 .

[30]  L. Allegra,et al.  Aspects of bronchial reactivity to prostaglandins and aspirin in asthmatic patients. , 1977, Respiration; international review of thoracic diseases.

[31]  L. Allegra,et al.  Clinical, functional and pathogenetic aspects of bronchial reactivity to prostaglandins F2alpha, E1, and E2. , 1976, Advances in prostaglandin and thromboxane research.

[32]  M. Hamberg,et al.  Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. , 1974, Proceedings of the National Academy of Sciences of the United States of America.