Potency ranking of triterpenoids as inducers of a cytoprotective enzyme and as inhibitors of a cellular inflammatory response via their electron affinity and their electrophilicity index.
暂无分享,去创建一个
[1] C. Wolf,et al. Activation of the NRF2 signaling pathway by copper-mediated redox cycling of para- and ortho-hydroquinones. , 2010, Chemistry & biology.
[2] R. Guérois,et al. Activation of NRF2 by Nitrosative Agents and H2O2 Involves KEAP1 Disulfide Formation* , 2010, The Journal of Biological Chemistry.
[3] R. Bensasson,et al. Comment on "Assessing the efficacy of nonsteroidal anti-inflammatory drugs through the quantum computation of molecular ionization energies". , 2009, The journal of physical chemistry. A.
[4] A. Dinkova-Kostova,et al. Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles , 2008, Proceedings of the National Academy of Sciences.
[5] M. Sporn,et al. A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin. , 2008, Cancer research.
[6] M. Sporn,et al. Prevention and Treatment of Experimental Estrogen Receptor – Negative Mammary Carcinogenesis by the Synthetic Triterpenoid CDDO-Methyl Ester and the Rexinoid LG100268 , 2008, Clinical Cancer Research.
[7] D. Kufe,et al. Triterpenoid CDDO-methyl ester inhibits the Janus-activated kinase-1 (JAK1)-->signal transducer and activator of transcription-3 (STAT3) pathway by direct inhibition of JAK1 and STAT3. , 2008, Cancer research.
[8] Vincent Zoete,et al. Two-step mechanism of induction of the gene expression of a prototypic cancer-protective enzyme by diphenols. , 2008, Chemical research in toxicology.
[9] D. Mazziotti,et al. Assessing the efficacy of nonsteroidal anti-inflammatory drugs through the quantum computation of molecular ionization energies. , 2007, The journal of physical chemistry. A.
[10] M. Sporn,et al. Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer , 2007, Nature Reviews Cancer.
[11] M. Sporn,et al. The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice. , 2007, Cancer research.
[12] M. Konopleva,et al. The triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and its derivatives elicit human lymphoid cell apoptosis through a novel pathway involving the unregulated mitochondrial permeability transition pore. , 2007, Cancer research.
[13] M. Sporn,et al. The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-κB activation through direct inhibition of IκB kinase β , 2006, Molecular Cancer Therapeutics.
[14] D. Kufe,et al. Triterpenoid CDDO-Me Blocks the NF-κB Pathway by Direct Inhibition of IKKβ on Cys-179* , 2006, Journal of Biological Chemistry.
[15] W. Berkel,et al. Pro-oxidant activity of flavonoids induces EpRE-mediated gene expression. , 2006, Chemical research in toxicology.
[16] M. Sporn,et al. Studies on the reactivity of CDDO, a promising new chemopreventive and chemotherapeutic agent: implications for a molecular mechanism of action. , 2005, Bioorganic & medicinal chemistry letters.
[17] Paul Talalay,et al. Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[18] Vincent Zoete,et al. Redox ranking of inducers of a cancer-protective enzyme via the energy of their highest occupied molecular orbital. , 2004, Free radical biology & medicine.
[19] Paul Talalay,et al. Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[20] L. Coussens,et al. Inflammation and cancer , 2002, Nature.
[21] M. Sporn,et al. A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide production. , 2002, Bioorganic & medicinal chemistry letters.
[22] Delano P. Chong,et al. Interpretation of the Kohn-Sham orbital energies as approximate vertical ionization potentials , 2002 .
[23] M. Sporn,et al. Synthetic oleanane and ursane triterpenoids with modified rings A and C: a series of highly active inhibitors of nitric oxide production in mouse macrophages. , 2000, Journal of medicinal chemistry.
[24] C. Angeli. Physical Interpretation of Koopmans' Theorem: A Criticism of the Current Didactic Presentation , 1998 .
[25] D. Covell,et al. Reactivity of the HIV-1 nucleocapsid protein p7 zinc finger domains from the perspective of density-functional theory. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[26] A. Filippetti. Electron affinity in density-functional theory in the local-spin-density approximation , 1998 .
[27] Luhua Lai,et al. A New Atom-Additive Method for Calculating Partition Coefficients , 1997, J. Chem. Inf. Comput. Sci..
[28] H. Bartsch,et al. Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. , 1994, Mutation research.
[29] P. Talalay,et al. Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[30] N. Heinrich,et al. On the use of koopmans' theorem to estimate negative electron affinities , 1986 .
[31] P. Talalay,et al. On the mechanisms of induction of cancer-protective enzymes: a unifying proposal. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[32] R. Mcweeny,et al. Orbital energies and Koopmans' theorem in open-shell Hartree-Fock theory , 1972 .
[33] A. Pullman. On the possibilities of correlating the redox potential of reversible systems to the molecular orbitals involved in the electron transfer , 1962 .
[34] Stuart A. Rice,et al. Quantum Chemistry: Methods and Applications , 1960 .
[35] Frederick Albert Matsen IV,et al. Electron Affinities, Methyl Affinities, and Ionization Energies of Condensed Ring Aromatic Hydrocarbons , 1956 .
[36] W. Moffitt. Term values in hybrid states , 1950, Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences.
[37] A. Maccoll. Reduction Potentials of Conjugated Systems , 1949, Nature.
[38] R. S. Mulliken. Molecular Orbital Method and Molecular Ionization Potentials , 1948 .
[39] A. Dinkova-Kostova,et al. The "Prochaska" microtiter plate bioassay for inducers of NQO1. , 2004, Methods in enzymology.
[40] J. Pezzuto,et al. Induction of quinone reductase as a primary screen for natural product anticarcinogens. , 2004, Methods in Enzymology.
[41] J. Parsonnet. Microbes and malignancy : infection as a cause of human cancers , 1999 .
[42] P. Talalay,et al. Phenolic antioxidants as inducers of anticarcinogenic enzymes. , 1992 .
[43] S. Colowick,et al. Methods in Enzymology , Vol , 1966 .
[44] T. Koopmans,et al. Über die Zuordnung von Wellenfunktionen und Eigenwerten zu den Einzelnen Elektronen Eines Atoms , 1934 .
[45] R. Virchow. Cellular pathology as based upon physiological and pathological histology ... / by Rudolf Virchow. Translated from the 2d ed. of the original by Frank Chance. With notes and numerous emendations, principally from MS. notes of the author , 1863 .