Implication of gut microbiota metabolites in cardiovascular and metabolic diseases
暂无分享,去创建一个
[1] C. Pepine,et al. Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure. , 2018, Clinical science.
[2] J. Sanderson,et al. Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota , 2018, bioRxiv.
[3] Aleksandra A. Kolodziejczyk,et al. Bile acids in glucose metabolism in health and disease , 2018, The Journal of experimental medicine.
[4] A. Molinaro,et al. Role of Bile Acids in Metabolic Control , 2018, Trends in Endocrinology & Metabolism.
[5] A. Goto,et al. Association between plasma concentrations of branched-chain amino acids and adipokines in Japanese adults without diabetes , 2018, Scientific Reports.
[6] Lin Shi,et al. Plasma metabolites associated with type 2 diabetes in a Swedish population: a case–control study nested in a prospective cohort , 2018, Diabetologia.
[7] S. Hazen,et al. Microbial modulation of cardiovascular disease , 2018, Nature Reviews Microbiology.
[8] C. Stanton,et al. Bile acids at the cross-roads of gut microbiome–host cardiometabolic interactions , 2017, Diabetology & Metabolic Syndrome.
[9] S. A. Arriola Apelo,et al. Restoration of metabolic health by decreased consumption of branched‐chain amino acids , 2017, The Journal of physiology.
[10] J. Blanchard,et al. Bacterial Branched-Chain Amino Acid Biosynthesis: Structures, Mechanisms, and Drugability. , 2017, Biochemistry.
[11] T. Spector,et al. Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome , 2017, Scientific Reports.
[12] Arthur Brady,et al. Strains, functions and dynamics in the expanded Human Microbiome Project , 2017, Nature.
[13] F. Rey,et al. Metabolic, Epigenetic, and Transgenerational Effects of Gut Bacterial Choline Consumption. , 2017, Cell host & microbe.
[14] N. Abumrad,et al. Bile acids and bariatric surgery. , 2017, Molecular aspects of medicine.
[15] Quan Gu,et al. Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance , 2017, Cell reports.
[16] Richard G. Lee,et al. The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. , 2017, Cell reports.
[17] J. Holst,et al. Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial , 2017, Scientific Reports.
[18] P. Langella,et al. Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria , 2017, Microbial Cell Factories.
[19] B. Staels,et al. Bile acid control of metabolism and inflammation in obesity, type 2 diabetes, dyslipidemia and NAFLD. , 2017 .
[20] Jussi Paananen,et al. Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study , 2017, Scientific Reports.
[21] A. El-Osta,et al. High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice , 2017, Circulation.
[22] H. Berthoud,et al. Gut-Brain Cross-Talk in Metabolic Control , 2017, Cell.
[23] T. Hansen,et al. Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels , 2017, Diabetologia.
[24] E. Chambers,et al. The diet‐derived short chain fatty acid propionate improves beta‐cell function in humans and stimulates insulin secretion from human islets in vitro , 2017, Diabetes, obesity & metabolism.
[25] C. Cho,et al. Trimethylamine-N-Oxide: Friend, Foe, or Simply Caught in the Cross-Fire? , 2017, Trends in Endocrinology & Metabolism.
[26] M. Vaneechoutte,et al. p-Cresyl Sulfate , 2017, Toxins.
[27] Di Zhang,et al. Metabolic regulation of gene expression through histone acylations , 2016, Nature Reviews Molecular Cell Biology.
[28] T. Spector,et al. Associations between branched chain amino acid intake and biomarkers of adiposity and cardiometabolic health independent of genetic factors: A twin study☆ , 2016, International journal of cardiology.
[29] Inês Barroso,et al. Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis , 2016, PLoS medicine.
[30] M. Ferruzzi,et al. Altered Transport and Metabolism of Phenolic Compounds in Obesity and Diabetes: Implications for Functional Food Development and Assessment. , 2016, Advances in nutrition.
[31] D. Raj,et al. Trimethylamine N-Oxide: The Good, the Bad and the Unknown , 2016, Toxins.
[32] S. Flavahan,et al. Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41. , 2016, Physiological genomics.
[33] P. Bork,et al. Human gut microbes impact host serum metabolome and insulin sensitivity , 2016, Nature.
[34] S. A. Arriola Apelo,et al. Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health. , 2016, Cell reports.
[35] F. Bäckhed,et al. Microbiota-Produced Succinate Improves Glucose Homeostasis via Intestinal Gluconeogenesis. , 2016, Cell metabolism.
[36] E. Zoetendal,et al. Effects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: A Randomized Double-Blind Placebo-Controlled Trial. , 2016, Cell metabolism.
[37] F. Bäckhed,et al. Diet–microbiota interactions as moderators of human metabolism , 2016, Nature.
[38] J. Borén,et al. Metabolic transformations of dietary polyphenols: comparison between in vitro colonic and hepatic models and in vivo urinary metabolites. , 2016, The Journal of nutritional biochemistry.
[39] F. Bäckhed,et al. From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites , 2016, Cell.
[40] F. Schick,et al. Relationship of Serum Trimethylamine N-Oxide (TMAO) Levels with early Atherosclerosis in Humans , 2016, Scientific Reports.
[41] K. Petersen,et al. Acetate mediates a microbiome-brain-β cell axis promoting metabolic syndrome , 2016, Nature.
[42] R. Roeder,et al. Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters , 2016, Molecular cell.
[43] A. Sulpizio,et al. L‐carnitine intake and high trimethylamine N‐oxide plasma levels correlate with low aortic lesions in ApoE−/− transgenic mice expressing hCETP , 2016, Atherosclerosis.
[44] S. Hazen,et al. Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk , 2016, Cell.
[45] J. Segre,et al. Signaling in Host-Associated Microbial Communities , 2016, Cell.
[46] Y. Bao,et al. Metabolomics Study of Roux-en-Y Gastric Bypass Surgery (RYGB) to Treat Type 2 Diabetes Patients Based on Ultraperformance Liquid Chromatography-Mass Spectrometry. , 2016, Journal of proteome research.
[47] S. Haffner,et al. Branched-Chain Amino Acids and Insulin Metabolism: The Insulin Resistance Atherosclerosis Study (IRAS) , 2016, Diabetes Care.
[48] Jun Wang,et al. Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota , 2015, Nature.
[49] Wen-Chang Chang,et al. Protective Effect of Vanillic Acid against Hyperinsulinemia, Hyperglycemia and Hyperlipidemia via Alleviating Hepatic Insulin Resistance and Inflammation in High-Fat Diet (HFD)-Fed Rats , 2015, Nutrients.
[50] A. von Eckardstein,et al. Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control. , 2015, Atherosclerosis.
[51] Ellen E. Blaak,et al. Short-chain fatty acids in control of body weight and insulin sensitivity , 2015, Nature Reviews Endocrinology.
[52] Fredrik H. Karlsson,et al. Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation , 2015, Cell metabolism.
[53] Gabi Kastenmüller,et al. A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control , 2015, Diabetologia.
[54] Jianping Ye,et al. Sodium butyrate epigenetically modulates high‐fat diet‐induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning , 2015, British journal of pharmacology.
[55] M. Trauner,et al. Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity , 2015, Journal of hepatology.
[56] P. Elliott,et al. Urinary metabolic signatures of human adiposity , 2015, Science Translational Medicine.
[57] B. Neuschwander‐Tetri,et al. Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial , 2015, The Lancet.
[58] D. Gauguier,et al. Plaque burden in HIV-infected patients is associated with serum intestinal microbiota-generated trimethylamine , 2015, AIDS.
[59] Omry Koren,et al. Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome , 2015, Nature.
[60] Jimmy D Bell,et al. Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults , 2014, Gut.
[61] N. Buys,et al. Effect of Probiotics on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials , 2014, Hypertension.
[62] E. Segal,et al. Artificial sweeteners induce glucose intolerance by altering the gut microbiota , 2014, Nature.
[63] N. Shimba,et al. Plasma amino acid profiles are associated with insulin, C-peptide and adiponectin levels in type 2 diabetic patients , 2014, Nutrition & Diabetes.
[64] G. Frost,et al. The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents , 2014, International Journal of Obesity.
[65] S. Yano,et al. Effects of uremic toxin p-cresol on proliferation, apoptosis, differentiation, and glucose uptake in 3T3-L1 cells. , 2014, Artificial organs.
[66] A. Rowland,et al. Inhibition of human drug-metabolising cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in vitro by uremic toxins , 2014, European Journal of Clinical Pharmacology.
[67] E. Zoetendal,et al. Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity. , 2014, Journal of hepatology.
[68] V. Tremaroli,et al. FXR is a molecular target for the effects of vertical sleeve gastrectomy , 2014, Nature.
[69] F. Bäckhed,et al. Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits , 2014, Cell.
[70] Christian Gieger,et al. Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach , 2013, Diabetes.
[71] S. Parkar,et al. Fecal microbial metabolism of polyphenols and its effects on human gut microbiota. , 2013, Anaerobe.
[72] J. Clemente,et al. Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice , 2013, Science.
[73] S. Mudaliar,et al. Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease. , 2013, Gastroenterology.
[74] P. Bork,et al. Richness of human gut microbiome correlates with metabolic markers , 2013, Nature.
[75] B. Aronow,et al. Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner , 2013, Obesity.
[76] G. Tsujimoto,et al. The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43 , 2013, Nature Communications.
[77] S. Hazen,et al. Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk. , 2013, The New England journal of medicine.
[78] F. Bushman,et al. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis , 2013, Nature Medicine.
[79] I. Wilson,et al. Hippurate: the natural history of a mammalian-microbial cometabolite. , 2013, Journal of proteome research.
[80] H. Flint,et al. Major phenylpropanoid-derived metabolites in the human gut can arise from microbial fermentation of protein. , 2013, Molecular nutrition & food research.
[81] J. Gordon,et al. Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation , 2013, Proceedings of the National Academy of Sciences.
[82] T. Hummel,et al. Human Trace Amine-Associated Receptor TAAR5 Can Be Activated by Trimethylamine , 2013, PloS one.
[83] Kevin D Young,et al. Indole production by the tryptophanase TnaA in Escherichia coli is determined by the amount of exogenous tryptophan. , 2013, Microbiology.
[84] Brian J. Bennett,et al. Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. , 2013, Cell metabolism.
[85] E. Edelman,et al. Uremic Serum and Solutes Increase Post–Vascular Interventional Thrombotic Risk Through Altered Stability of Smooth Muscle Cell Tissue Factor , 2012, Circulation.
[86] Qiang Feng,et al. A metagenome-wide association study of gut microbiota in type 2 diabetes , 2012, Nature.
[87] M. Blaser,et al. Antibiotics in early life alter the murine colonic microbiome and adiposity , 2012, Nature.
[88] J. Nicholson,et al. Host-Gut Microbiota Metabolic Interactions , 2012, Science.
[89] J. Nicholson,et al. Genetic determinants of metabolism in health and disease: from biochemical genetics to genome-wide associations , 2012, Genome Medicine.
[90] Hua V. Lin,et al. Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms , 2012, PloS one.
[91] L. Calani,et al. Identification of microbial metabolites derived from in vitro fecal fermentation of different polyphenolic food sources. , 2012, Nutrition.
[92] Wei Sun,et al. The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon. , 2011, Cell metabolism.
[93] V. Mootha,et al. Metabolite profiles and the risk of developing diabetes , 2011, Nature Medicine.
[94] Brian J. Bennett,et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease , 2011, Nature.
[95] Oliver Fiehn,et al. Plasma Metabolomic Profiles Reflective of Glucose Homeostasis in Non-Diabetic and Type 2 Diabetic Obese African-American Women , 2010, PloS one.
[96] Christian Gieger,et al. Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting , 2010, PloS one.
[97] E. Want,et al. Global metabolic profiling procedures for urine using UPLC–MS , 2010, Nature Protocols.
[98] G. Mingrone,et al. Gut microbiome-derived metabolites characterize a peculiar obese urinary metabotype , 2010, International Journal of Obesity.
[99] P. Bork,et al. A human gut microbial gene catalogue established by metagenomic sequencing , 2010, Nature.
[100] E. Tai,et al. Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men , 2010, Diabetologia.
[101] A. Schwiertz,et al. Microbiota and SCFA in Lean and Overweight Healthy Subjects , 2010, Obesity.
[102] M. Miyata,et al. Administration of Ampicillin Elevates Hepatic Primary Bile Acid Synthesis through Suppression of Ileal Fibroblast Growth Factor 15 Expression , 2009, Journal of Pharmacology and Experimental Therapeutics.
[103] M. Blaser,et al. What are the consequences of the disappearing human microbiota? , 2009, Nature Reviews Microbiology.
[104] Z. Massy,et al. Serum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients. , 2009, Clinical journal of the American Society of Nephrology : CJASN.
[105] John C Lindon,et al. Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism , 2009, Proceedings of the National Academy of Sciences.
[106] W. Cefalu,et al. Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice , 2009, Diabetes.
[107] Svati H Shah,et al. A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. , 2009, Cell metabolism.
[108] G. Cresci,et al. GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. , 2009, Cancer research.
[109] B. Roe,et al. A core gut microbiome in obese and lean twins , 2008, Nature.
[110] Ian D. Wilson,et al. Metabolic Phenotyping in Health and Disease , 2008, Cell.
[111] Ian J. Brown,et al. Human metabolic phenotype diversity and its association with diet and blood pressure , 2008, Nature.
[112] T. Ebbels,et al. Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts , 2007, Nature Protocols.
[113] T. Hashimoto,et al. 1H NMR-based metabonomic analysis of urine from young spontaneously hypertensive rats. , 2007, Journal of pharmaceutical and biomedical analysis.
[114] H. Yamashita,et al. Improvement of Obesity and Glucose Tolerance by Acetate in Type 2 Diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) Rats , 2007, Bioscience, biotechnology, and biochemistry.
[115] Dominique Gauguier,et al. Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models , 2007, Nature Genetics.
[116] R. Cox,et al. A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human. , 2007, Physiological genomics.
[117] M. McCarthy,et al. Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice , 2006, Proceedings of the National Academy of Sciences.
[118] T. Mendoza,et al. Changes in Gene Expression Foreshadow Diet-Induced Obesity in Genetically Identical Mice , 2006, PLoS Genetics.
[119] J. Lindon,et al. Pharmaco-metabonomic phenotyping and personalized drug treatment , 2006, Nature.
[120] E. Purdom,et al. Diversity of the Human Intestinal Microbial Flora , 2005, Science.
[121] I. Wilson,et al. Gut microorganisms, mammalian metabolism and personalized health care , 2005, Nature Reviews Microbiology.
[122] P. Whelton,et al. Effect of dietary fiber intake on blood pressure: a meta-analysis of randomized, controlled clinical trials , 2005, Journal of hypertension.
[123] Ting Wang,et al. The gut microbiota as an environmental factor that regulates fat storage. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[124] S. Dowell,et al. The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids* , 2003, The Journal of Biological Chemistry.
[125] Bernard Thorens,et al. Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet. , 2002, American journal of physiology. Endocrinology and metabolism.
[126] J. Lindon,et al. Metabonomics: a platform for studying drug toxicity and gene function , 2002, Nature Reviews Drug Discovery.
[127] D. Jenden,et al. Choline deficiency: A cause of hepatic steatosis during parenteral nutrition that can be reversed with intravenous choline supplementation , 1995, Hepatology.
[128] C. Nutting,et al. Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. , 1991, The American journal of physiology.
[129] M. Mulvany,et al. Short chain fatty acids dilate isolated human colonic resistance arteries. , 1990, Gut.
[130] P. Felig,et al. Plasma amino acid levels and insulin secretion in obesity. , 1969, The New England journal of medicine.
[131] B. Wostmann,et al. Fecal neutral steroids and bile acids from germfree rats. , 1969, Journal of lipid research.
[132] S. Fajans,et al. Stimulation of insulin secretion by amino acids. , 1966, The Journal of clinical investigation.
[133] E. Edelman,et al. The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia. , 2016, Journal of the American Society of Nephrology : JASN.
[134] Nigel F. Delaney,et al. Effects of sodium benzoate, a widely used food preservative, on glucose homeostasis and metabolic profiles in humans. , 2015, Molecular genetics and metabolism.
[135] Jens Roat Kultima,et al. Disentangling the effects of type 2 diabetes and metformin on the human gut microbiota , 2015, Nature.