Microwave ablation therapy for treating primary and secondary lung tumours: technical note

PurposeThe purpose of our study was to retrospectively evaluate the feasibility, safety and effectiveness of microwave ablation (MWA) in nine patients with unresectable lung tumour.Materials and methodsTen lesions were treated in ten ablation sessions in nine patients. The treatments were performed with a microwave generator with 45 W and 915 MHz connected to a 14.5-gauge antenna for 10 min. Antenna placement was performed with computed tomography (CT) fluoroscopy guidance or XperGuide. All patients underwent CT follow-up at 1, 3 and 6 months from the procedure.ResultsTechnical success was obtained in all cases; mortality at 30 days was 0%.ConclusionsThis study shows that in selected patients, MWA is a valid alternative to other ablative techniques. Further studies are required to demonstrate the short- and long-term effects of this technique and to make a comparison with other available ablation systems, especially with radiofrequency.RiassuntoObiettivoLo scopo dello studio è stato quello di valutare il successo tecnico, la sicurezza, l’efficacia della metodica del trattamento ablativo mediante microonde (MW) in 9 pazienti affetti da neoplasia polmonare non trattabile chirurgicamente.Materiali e metodiSono state trattate 10 masse polmonari in 10 sessioni d’ablazione in 9 pazienti. È stato utilizzato un sistema ablativo costituito da un generatore di MW a 45 W e 915 MHz connesso ad un antenna 14,5 G, per un tempo di ablazione totale di 10 minuti. Il posizionamento dell’antenna è stato eseguito sotto guida fluoro-tomografia computerizzata (TC) o XperGuide. I pazienti sono stati sottoposti a follow-up mediante TC a 1, 3, 6 mesi dalla procedura.RisultatiSi è ottenuto un successo tecnico in tutti i casi; il tasso di mortalità a 30 giorni è stato dello 0%.ConclusioniQuesto studio dimostra che, in pazienti selezionati, la termoablazione con microonde rappresenta una valida alternativa ad altre tecniche ablative. Sono tuttavia necessari ulteriori studi per confermare a breve e lungo termine l’efficacia di questa metodologia e permettere un confronto con altri sistemi ablativi, in particolare rispetto alla radiofrequenza.

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