Overexpression of SERPIN B3 promotes epithelial proliferation and lung fibrosis in mice

[1]  Moisés Selman,et al.  Idiopathic pulmonary fibrosis , 2011, The Lancet.

[2]  M. Gyetko,et al.  Recent advances in molecular targets and treatment of idiopathic pulmonary fibrosis: focus on TGFbeta signaling and the myofibroblast. , 2009, Current medicinal chemistry.

[3]  T. Welte,et al.  Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis , 2008, Respiratory research.

[4]  P. Bird,et al.  The role of serpins in vertebrate immunity. , 2008, Tissue antigens.

[5]  P. Pontisso,et al.  Overexpression of squamous cell carcinoma antigen in idiopathic pulmonary fibrosis: clinicopathological correlations , 2008, Thorax.

[6]  R. Breuer,et al.  Telomerase activity in bleomycin-induced epithelial cell apoptosis and lung fibrosis , 2007, European Respiratory Journal.

[7]  D. Sheppard,et al.  Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix , 2006, Proceedings of the National Academy of Sciences.

[8]  Y. Nasuhara,et al.  Extracellular matrix metalloproteinase inducer in interstitial pneumonias. , 2006, Human pathology.

[9]  M. Selman,et al.  Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers. , 2006, Proceedings of the American Thoracic Society.

[10]  K. Kadoya,et al.  Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH2-terminal kinase , 2006, The Journal of cell biology.

[11]  S. Garbisa,et al.  Inhibition of Leukocyte Elastase, Polymorphonuclear Chemoinvasion, and Inflammation-Triggered Pulmonary Fibrosis by a 4-Alkyliden-β-lactam with a Galloyl Moiety , 2006, Journal of Pharmacology and Experimental Therapeutics.

[12]  G. Appendino,et al.  Hyperforin Inhibits Cancer Invasion and Metastasis , 2004, Cancer Research.

[13]  T. Welte,et al.  Pivotal role of cathepsin K in lung fibrosis. , 2004, The American journal of pathology.

[14]  P. Pontisso,et al.  Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma , 2004, British Journal of Cancer.

[15]  R. Mason,et al.  Role of Alveolar Type II Epithelial Cells in Pulmonary Fibrosis , 2003 .

[16]  B. Uhal,et al.  Essential roles for angiotensin receptor AT1a in bleomycin-induced apoptosis and lung fibrosis in mice. , 2003, The American journal of pathology.

[17]  B. Uhal,et al.  Epithelial apoptosis in the initiation of lung fibrosis , 2003, European Respiratory Journal.

[18]  V. Pankratz,et al.  Primary pulmonary carcinoma in patients with idiopathic pulmonary fibrosis. , 2002, Mayo Clinic proceedings.

[19]  G. Izbicki,et al.  Time course of bleomycin‐induced lung fibrosis , 2002, International journal of experimental pathology.

[20]  A. Alberti,et al.  Cloning and Expression of a Novel Hepatitis B Virus-binding Protein from HepG2 Cells* , 2001, The Journal of Biological Chemistry.

[21]  J. Whisstock,et al.  The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins , 2001, The Journal of Biological Chemistry.

[22]  C. Lisboa,et al.  Bleomycin-induced chronic lung damage does not resemble human idiopathic pulmonary fibrosis. , 2001, American journal of respiratory and critical care medicine.

[23]  G. Silverman,et al.  Suppression of a squamous cell carcinoma (SCC)-related serpin, SCC antigen, inhibits tumor growth with increased intratumor infiltration of natural killer cells. , 2001, Cancer research.

[24]  H. Hirakawa,et al.  Squamous cell carcinoma antigen suppresses radiation-induced cell death , 2001, British Journal of Cancer.

[25]  A. Pardo,et al.  Idiopathic Pulmonary Fibrosis: Prevailing and Evolving Hypotheses about Its Pathogenesis and Implications for Therapy , 2001, Annals of Internal Medicine.

[26]  M. Selman,et al.  AMERICAN THORACIC SOCIETY; EUROPEAN RESPIRATORY SOCIETY; AMERICAN COLLEGE OF CHEST PHYSICIANS. IDIOPATHIC PULMONARY FIBROSIS: PREVAILING AND EVOLVING HYPOTHESES ABOUT ITS PATHOGENESIS AND IMPLICATIONS FOR THERAPY , 2001 .

[27]  T. Betsuyaku,et al.  Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin. , 2000, The American journal of pathology.

[28]  J. Tamaoki,et al.  The Fas/Fas-ligand system is not required for bleomycin-induced pulmonary fibrosis in mice. , 2000, American journal of respiratory and critical care medicine.

[29]  T. Whiteside,et al.  Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1 , 2000, British Journal of Cancer.

[30]  R. Hubbard,et al.  Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study. , 2000, American journal of respiratory and critical care medicine.

[31]  K. Kubo,et al.  Bleomycin stimulates lung epithelial cells to release neutrophil and monocyte chemotactic activities. , 1999, The American journal of physiology.

[32]  H. Chapman,et al.  Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis. , 1998, Biochemistry.

[33]  H. Kato.  Expression and function of squamous cell carcinoma antigen. , 1996, Anticancer research.

[34]  K. Flanders,et al.  Cellular localization of transforming growth factor-beta expression in bleomycin-induced pulmonary fibrosis. , 1995, The American journal of pathology.

[35]  S. Ben‐Sasson,et al.  Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation , 1992, The Journal of cell biology.

[36]  R. Crystal,et al.  Alveolitis: the key to the interstitial lung disorders. , 1982, Thorax.

[37]  A. Liebow,et al.  Relationship of interstitial pneumonia honeycombing and atypical epithelial proliferation to cancer of the lung , 1965, Cancer.