Motif in Mediating TCR-CD8 Cooperation -Chain Connecting Peptide α A Role for the

Dieter Naeher, Immanuel F. Luescher and Ed Palmerhttp://www.jimmunol.org/content/169/6/2964J Immunol€2002; 169:2964-2970; ;Referenceshttp://www.jimmunol.org/content/169/6/2964.full#ref-list-1This article cites 55 articles, 21 of which you can access for free at: Subscriptionshttp://jimmunol.org/subscriptionsInformation about subscribing to The Journal of Immunology is online at: Permissionshttp://www.aai.org/ji/copyright.htmlSubmit copyright permission requests at: Email Alertshttp://jimmunol.org/cgi/alerts/etocReceive free email-alerts when new articles cite this article. Sign up at:

[1]  E. Palmer,et al.  Defective Signaling to Fyn by a T Cell Antigen Receptor Lacking the α-Chain Connecting Peptide Motif* , 2001, The Journal of Biological Chemistry.

[2]  S. Jameson,et al.  T-cell-receptor affinity and thymocyte positive selection , 1996, Nature.

[3]  C. Rudd,et al.  The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[4]  B. Alarcón,et al.  CD3δ couples T-cell receptor signalling to ERK activation and thymocyte positive selection , 2000, Nature.

[5]  J. Altman,et al.  Role of CD8β Domains in CD8 Coreceptor Function , 2000 .

[6]  R. Germain,et al.  MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8 , 1992, Nature.

[7]  S. Nathenson,et al.  Evidence that the antigen receptors of cytotoxic T lymphocytes interact with a common recognition pattern on the H-2Kb molecule. , 1995, Immunity.

[8]  E. Palmer,et al.  Positive Selection Through a Motif in the αβ T Cell Receptor , 1998 .

[9]  P. Romero,et al.  Photoaffinity labeling of the T cell receptor on cloned cytotoxic T lymphocytes by covalent photoreactive ligand. , 1994, The Journal of biological chemistry.

[10]  Hidehiro Kishimoto,et al.  The thymus and negative selection , 2002, Immunological reviews.

[11]  P. Romero,et al.  CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes , 1995, Nature.

[12]  L R Pease,et al.  Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen. , 1998, Science.

[13]  W. Fung-Leung,et al.  Peptide-induced positive selection of TCR transgenic thymocytes in a coreceptor-independent manner. , 1997, Immunity.

[14]  H. Pircher,et al.  CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny , 1993, European journal of immunology.

[15]  P. Marrack,et al.  Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. , 1989, Journal of immunology.

[16]  P. Ohashi,et al.  Signals involved in thymocyte positive and negative selection. , 1999, Seminars in immunology.

[17]  T. Potter,et al.  Recognition by CD8 on cytotoxic T lymphocytes is ablated by several substitutions in the class I alpha 3 domain: CD8 and the T-cell receptor recognize the same class I molecule. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[18]  Kristin A. Hogquist,et al.  T cell receptor antagonist peptides induce positive selection , 1994, Cell.

[19]  R. Blaese,et al.  Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[20]  J. Bolen,et al.  Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways , 1989, The Journal of experimental medicine.

[21]  S. Levin,et al.  Positive and Negative Selection of Thymocytes Depends on Lck Interaction with the CD4 and CD8 Coreceptors1 , 2001, The Journal of Immunology.

[22]  A. Smolyar,et al.  Identification of a common docking topology with substantial variation among different TCR–peptide–MHC complexes , 1998, Current Biology.

[23]  J. Watson.  Continuous proliferation of murine antigen-specific helper T lymphocytes in culture , 1979, The Journal of experimental medicine.

[24]  J. Sprent,et al.  The thymus and negative selection , 2000, Immunologic research.

[25]  Y. Chien,et al.  CD4 augments the response of a T cell to agonist but not to antagonist ligands. , 1997, Immunity.

[26]  P. A. Peterson,et al.  CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes , 1996, Nature.

[27]  G. Evans,et al.  Co-engagement of CD8 with the T cell receptor is required for negative selection , 1991, Nature.

[28]  E. Palmer,et al.  Class I and class II MHC gene products differentially affect the fate of V beta 5 bearing thymocytes. , 1990, The Journal of molecular and cellular immunology : JMCI.

[29]  S. Jameson,et al.  Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. , 1999, Immunity.

[30]  P. A. Peterson,et al.  Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes. , 1998, Immunity.

[31]  Robyn L. Stanfield,et al.  An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex , 1996, Science.

[32]  O. Acuto,et al.  Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex , 1995, The Journal of experimental medicine.

[33]  D. Kioussis,et al.  Inducible expression of a p56Lck transgene reveals a central role for Lck in the differentiation of CD4 SP thymocytes. , 2000, Immunity.

[34]  J. Sprent,et al.  The thymus and central tolerance. , 2001, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[35]  M. Bevan,et al.  Selecting and maintaining a diverse T-cell repertoire , 1999, Nature.

[36]  Barbara Hausmann,et al.  A motif in the αβ T-cell receptor controls positive selection by modulating ERK activity , 2000, Nature.

[37]  E. Palmer,et al.  A motif within the T cell receptor alpha chain constant region connecting peptide domain controls antigen responsiveness. , 1996, Immunity.

[38]  Z. Eshhar,et al.  Lymphoid Cell Surface Interaction Structures Detected Using Cytolysis‐Inhibiting Monoclonal Antibodies , 1982, Immunological reviews.

[39]  Partho Ghosh,et al.  Structure of the complex between human T-cell receptor, viral peptide and HLA-A2 , 1996, Nature.

[40]  H. Land,et al.  Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. , 1990, Nucleic acids research.

[41]  G. Anderson,et al.  Positive selection of thymocytes: the long and winding road. , 1999, Immunology today.

[42]  M. Peitsch,et al.  Structural analysis of TCR-ligand interactions studied on H-2Kd-restricted cloned CTL specific for a photoreactive peptide derivative. , 1995, Immunity.

[43]  Mark I. Greene,et al.  Control of MHC Restriction by TCR Vα CDR1 and CDR2 , 1996, Science.

[44]  F. Chan,et al.  A role for the cytoplasmic tail of the β chain of CD8 in thymic selection , 1994 .

[45]  Miller Ad,et al.  Improved Retroviral Vectors for Gene Transfer and Expression , 1989 .

[46]  E. Palmer,et al.  An analysis of sequence variation in the beta chain framework and complementarity determining regions of an allo-reactive T cell receptor. , 1994, Molecular immunology.

[47]  H. Nakauchi,et al.  Requirement for CD8 beta chain in positive selection of CD8-lineage T cells. , 1994, Science.

[48]  M. Bevan,et al.  CD8 lineage commitment in the absence of CD8. , 1997, Immunity.

[49]  S. Valitutti,et al.  The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement. , 1998, Journal of immunology.

[50]  B. Malissen,et al.  Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a nonfunctional α‐mRNA of BW5147 origin , 1989, European journal of immunology.

[51]  D. Littman,et al.  Requirement for CD8-major histocompatibility complex class I interaction in positive and negative selection of developing T cells , 1992, The Journal of experimental medicine.

[52]  E. Palmer,et al.  T Cell Receptor (TCR) Antagonism without a Negative Signal: Evidence from T Cell Hybridomas Expressing Two Independent TCRs , 1999, The Journal of experimental medicine.