The critical review of methodologies and approaches to assess the inherent skin sensitization potential (skin allergies) of chemicals Part II

To identify specific cases, classes or specific use situations of chemicals for which ‘safety thresholds' or ‘safety limits' were set (in regulations, standards, in scientific research/clinical work, etc.) and critically review the scientific and methodological parameters used to set those limits.

[1]  C. Hansson,et al.  Stereochemical Considerations on Concomitant Allergic Contact Dermatitis to Ester of the cis-trans Isomeric Compounds Maleic Acid and Fumaric Acid , 2003, Skin Pharmacology and Physiology.

[2]  Lucas Smith,et al.  Classification, packaging and labelling of dangerous substances , 2014 .

[3]  S. Seidenari,et al.  Monitoring levels of preservative sensitivity in Europe , 2002, Contact dermatitis.

[4]  P. V. van Erp,et al.  Life-threatening contact urticaria from glove powder. , 1986, Contact dermatitis.

[5]  S. John,et al.  Decreasing incidence of occupational contact urticaria caused by natural rubber latex allergy in German health care workers. , 2004, The Journal of allergy and clinical immunology.

[6]  G. Nohynek,et al.  Sensitivity and specificity of the consumer open skin allergy test as a method of prediction of contact dermatitis to hair dyes. , 2005, European journal of dermatology : EJD.

[7]  J. Johansen,et al.  Patch test dose–response study of p‐phenylenediamine: thresholds and anatomical regional differences , 2006, Contact dermatitis.

[8]  A. Linneberg,et al.  The prevalence and morbidity of sensitization to fragrance mix I in the general population , 2009, The British journal of dermatology.

[9]  H. Wellendorf,et al.  Permeability of different types of medical protective gloves to acrylic monomers. , 2003, European journal of oral sciences.

[10]  C. Allenby,et al.  Influence of detergent washing powders on minimal eliciting patch test concentrations of nickel and chromium , 1983, Contact dermatitis.

[11]  Torkil Menné,et al.  Formaldehyde‐releasers: relationship to formaldehyde contact allergy. Contact allergy to formaldehyde and inventory of formaldehyde‐releasers , 2009, Contact dermatitis.

[12]  P. Frosch,et al.  Quantitative patch and repeated open application testing in methyldibromo glutaronitrile‐sensitive patients , 2005, Contact dermatitis.

[13]  T. Menné,et al.  Patch test reactivity to nickel alloys , 1987, Contact dermatitis.

[14]  David A. Basketter,et al.  Evaluation of the skin sensitizing potency of chemicals by using the existing methods and considerations of relevance for elicitation , 2005, Contact dermatitis.

[15]  B. Thiers.  para-Phenylenediamine: the profile of an important allergen. Results of the IVDK , 2009 .

[16]  S. Johnsson,et al.  A method for measuring dermal exposure to multifunctional acrylates. , 1999, Journal of environmental monitoring : JEM.

[17]  O. Faber,et al.  Penetration of protective gloves by allergens and irritants. , 1973, Transactions of the St. John's Hospital Dermatological Society.

[18]  N. Hjorth,et al.  Patch test sensitivity to Kathon® CG , 1986, Contact dermatitis.

[19]  T. Agner,et al.  Methyldibromoglutaronitrile in leave‐on products elicits contact allergy at low concentration , 2004, The British journal of dermatology.

[20]  Wolfgang Uter,et al.  Acceptable risk of contact allergy in the general population assessed by CE-DUR--a method to detect and categorize contact allergy epidemics based on patient data. , 2009, Regulatory toxicology and pharmacology : RTP.

[21]  T. Menné,et al.  Evaluation of the dimethylglyoxime stick test for the detection of nickel. , 1987, Dermatosen in Beruf und Umwelt. Occupation and environment.

[22]  I. Kimber,et al.  Local lymph node assay responses to paraphenylenediamine: intra‐ and inter‐laboratory evaluations , 1999, Journal of applied toxicology : JAT.

[23]  J. Johansen,et al.  Experimental nickel elicitation thresholds – a review focusing on occluded nickel exposure , 2005, Contact dermatitis.

[24]  T. Menné,et al.  Repeated exposures to cobalt or chromate on the hands of patients with hand eczema and contact allergy to that metal , 2000, Contact dermatitis.

[25]  T. Rantanen.  The cause of the Chinese sofa/chair dermatitis epidemic is likely to be contact allergy to dimethylfumarate, a novel potent contact sensitizer , 2008, The British journal of dermatology.

[26]  C. Geisler,et al.  Repeated exposure to hair dye induces regulatory T cells in mice , 2010, The British journal of dermatology.

[27]  M. Hannuksela.  Rapid increase in contact allergy to Kathon® CG in Finland , 1986, Contact dermatitis.

[28]  J. Thyssen,et al.  Temporal trends of preservative allergy in Denmark (1985–2008) , 2010, Contact dermatitis.

[29]  Robert C. Reid,et al.  State-of-the-Art Review of Permeation Testing and the Interpretation of Its Results , 1988 .

[30]  H. K. Lee,et al.  Induction of formaldehyde sensitivity in guinea pigs. , 1984, Toxicology and applied pharmacology.

[31]  G. Kasting,et al.  Hydroxyisohexyl 3‐cyclohexene carboxaldehyde allergy: relationship between patch test and repeated open application test thresholds , 2009, The British journal of dermatology.

[32]  Altmeyer,et al.  Treatment of psoriasis with fumaric acid esters: results of a prospective multicentre study , 1998, The British journal of dermatology.

[33]  S. Wakelin,et al.  The effect of patch duration on the elicitation of para‐phenylenediamine contact allergy , 1998, Contact dermatitis.

[34]  H. Maibach,et al.  Dose‐response assessments of Kathon® biocide (I). Diagnostic use and diagnostic threshold patch testing with sensitized humans , 1985, Contact dermatitis.

[35]  J. Hegewald,et al.  Contact allergy to thiurams: multifactorial analysis of clinical surveillance data collected by the IVDK network , 2009, International archives of occupational and environmental health.

[36]  D. Paustenbach,et al.  An environmental hazard assessment of low-level dermal exposure to hexavalent chromium in solution among chromium-sensitized volunteers. , 1999, Journal of occupational and environmental medicine.

[37]  C. Nieboer,et al.  Systemic therapy with fumaric acid derivates: new possibilities in the treatment of psoriasis. , 1989, Journal of the American Academy of Dermatology.

[38]  A. Basomba,et al.  Anaphylaxis produced by rubber glove contact. Case reports and immunological identification of the antigens involved , 1989, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[39]  B. Gruvberger,et al.  Can an imidazolidinyl urea‐preserved corticosteroid cream be safely used in individuals hypersensitive to formaldehyde? , 2006, Contact dermatitis.

[40]  L. Horev,et al.  AISI 316L Stainless-Steel Ear Piercing Post Assembly Does Not Cause Dermatitis in Nickel-Sensitive Subjects , 2003, Exogenous Dermatology.

[41]  Ian Kimber,et al.  Compilation of Historical Local Lymph Node Data for Evaluation of Skin Sensitization Alternative Methods , 2005, Dermatitis : contact, atopic, occupational, drug.

[42]  Anne Marie Api,et al.  Implementation of the dermal sensitization Quantitative Risk Assessment (QRA) for fragrance ingredients. , 2008, Regulatory toxicology and pharmacology : RTP.

[43]  D. Basketter,et al.  A general population from Thailand: incidence of common allergens with emphasis on para‐phenylenediamine , 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[44]  T. Risby,et al.  Allergic contact dermatitis to nickel: bioavailability from consumer products and provocation threshold. , 1988, Journal of the American Academy of Dermatology.

[45]  D. Basketter,et al.  The impact of exposure variables on the induction of skin sensitization , 2006, Contact dermatitis.

[46]  E. Lönnroth,et al.  Resistance of Medical Gloves to Permeation by Methyl Methacrylate (MMA), Ethylene Glycol Dimethacrylate (EGDMA), and 1,4-Butanediol Dimethacrylate (1,4-BDMA) , 2003, International journal of occupational safety and ergonomics : JOSE.

[47]  R. Fenske.  Dermal exposure assessment techniques. , 1993, The Annals of occupational hygiene.

[48]  R J Safford,et al.  The Dermal Sensitisation Threshold- a TTC approach for allergic contact dermatitis. , 2008, Regulatory toxicology and pharmacology : RTP.

[49]  K. Malten,et al.  Permeability of surgeons' gloves to methyl methacrylate. , 1983, Acta orthopaedica Scandinavica.

[50]  D. Basketter,et al.  Dose–time relationships for elicitation of contact allergy to para‐phenylenediamine , 2002, Contact dermatitis.

[51]  D. Basketter,et al.  Investigation of the threshold for allergic reactivity to chromium , 2001, Contact dermatitis.

[52]  A. Alomar,et al.  Contact dermatitis to dimethylfumarate in armchairs , 2009, Allergy.

[53]  F. Horsfall.  Formaldehyde Hypersensitiveness an Experimental Study , 1934, The Journal of Immunology.

[54]  T. Yamano,et al.  Skin sensitization potency and cross‐reactivity of p‐phenylenediamine and its derivatives evaluated by non‐radioactive murine local lymph node assay and guinea‐pig maximization test , 2009, Contact dermatitis.

[55]  T. Reunala,et al.  Surgical latex glove allergy: characterization of rubber protein allergens by immunoblotting. , 1991, International archives of allergy and applied immunology.

[56]  J. Montelius,et al.  Sensitizing potential in mice, guinea pig and man of the preservative Euxyl® K 400 and its ingredient methyldibromo glutaronitrile , 1999, Contact dermatitis.

[57]  C. T. Mathias,et al.  Contact dermatitis to a new biocide (Tektamer 38®) used in a paste glue formulation , 1983, Contact dermatitis.

[58]  C. Zachariae,et al.  An evaluation of dose/unit area and time as key factors influencing the elicitation capacity of methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) in MCI/MI‐allergic patients , 2006, Contact dermatitis.

[59]  J. Pegum.  Penetration of protective gloves by epoxy resin , 1979, Contact dermatitis.

[60]  J. Johansen,et al.  Nickel allergy: relationship between patch test and repeated open application test thresholds , 2007, The British journal of dermatology.

[61]  B. Gruvberger,et al.  An epidemic of furniture‐related dermatitis: searching for a cause , 2010, The British journal of dermatology.

[62]  J. Thyssen,et al.  Epidemiological data on consumer allergy to p‐phenylenediamine , 2008, Contact dermatitis.

[63]  K. Turjanmaa.  Incidence of immediate allergy to latex gloves in hospital personnel , 1987, Contact dermatitis.

[64]  D. Basketter,et al.  Elicitation response characteristics to permanent hair dye in paraphenylenediamine‐allergic volunteers , 2006, Contact dermatitis.

[65]  P. Friedmann.  The immunology of allergic contact dermatitis: the DNCB story. , 1990, Advances in dermatology.

[66]  G Frank Gerberick,et al.  Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients. , 2008, Regulatory toxicology and pharmacology : RTP.

[67]  T. Menné,et al.  Quantitative aspects of contact allergy to chromium and exposure to chrome‐tanned leather , 2002, Contact dermatitis.

[68]  G. Mellström,et al.  Discomfort from rubber gloves indicating contact urticaria , 1986, Contact dermatitis.

[69]  J. Olsen,et al.  The European Commission , 2020, The European Union.

[70]  T. Menné,et al.  Regulation of nickel exposure in Denmark , 1990, Contact dermatitis.

[71]  S. Tarlo,et al.  Control of airborne latex by use of powder-free latex gloves. , 1994, The Journal of allergy and clinical immunology.

[72]  R. Huggins,et al.  Testing of gloves for permeability to UV-curable acrylate coatings. , 1987, American Industrial Hygiene Association Journal.

[73]  H. Dickel,et al.  Quantitative patch and repeated open application testing in hydroxyisohexyl 3‐cyclohexene carboxaldehyde sensitive‐patients , 2009, Contact dermatitis.

[74]  T. Estlander,et al.  Dermatitis and urticaria from rubber and plastic gloves , 1986, Contact dermatitis.

[75]  A. Linneberg,et al.  Nickel allergy in Danish women before and after nickel regulation. , 2009, The New England journal of medicine.

[76]  S. Seidenari,et al.  Repeated open application test with methyldibromo glutaronitrile, a multicentre study within the EECDRG , 2005, Contact dermatitis.

[77]  I. Dahlquist,et al.  Contact allergy to the preservative Kathon® CG , 1986, Contact dermatitis.

[78]  R. Vermeulen,et al.  DREAM: a method for semi-quantitative dermal exposure assessment. , 2003, The Annals of occupational hygiene.

[79]  I Kimber,et al.  Classification of contact allergens according to potency: proposals. , 2003, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[80]  O. Vandenplas,et al.  Latex‐induced occupational asthma: time trend in incidence and relationship with hospital glove policies , 2009, Allergy.

[81]  J. Pegum,et al.  Contact Dermatitis from Penetration of Rubber Gloves by Acrylic Monomer , 1971, British medical journal.

[82]  J. M. Smith,et al.  Kathon biocide: manifestation of delayed contact dermatitis in guinea pigs is dependent on the concentration for induction and challenge. , 1983, The Journal of investigative dermatology.

[83]  S. Felter,et al.  Understanding fragrance allergy using an exposure‐based risk assessment approach , 2001, Contact dermatitis.

[84]  J. Johansen,et al.  Methyldibromoglutaronitrile in rinse‐off products causes allergic contact dermatitis: an experimental study , 2004, The British journal of dermatology.

[85]  C. Zachariae,et al.  Methyldibromo glutaronitrile: clinical experience and exposure‐based risk assessment , 2003, Contact dermatitis.

[86]  M. Sugiura,et al.  Experimental study on skin sensitization potencies and cross‐reactivities of hair‐dye‐related chemicals in guinea pigs , 2000, Contact dermatitis.

[87]  C. Foti,et al.  Occupational allergic contact dermatitis associated with dimethyl fumarate in clothing , 2009, Contact dermatitis.

[88]  A. Boman,et al.  Guinea pig maximization tests with formaldehyde releasers , 1984, Contact dermatitis.

[89]  A. Heratizadeh,et al.  Quantitative repeated open application testing with a rinse‐off product in methyldibromo glutaronitrile‐sensitive patients: results of the IVDK , 2010, Contact dermatitis.

[90]  C. Geisler,et al.  Consumer available permanent hair dye products cause major allergic immune activation in an animal model , 2010, The British journal of dermatology.

[91]  M. Bruze,et al.  Individual variation in nickel patch test reactivity. , 1999, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

[92]  W. Herman,et al.  A Laboratory Evaluation of Standard Leakage Tests for Surgical & Examination Gloves , 1989, Journal of clinical engineering.

[93]  A M Kligman,et al.  The identification of contact allergens by human assay. 3. The maximization test: a procedure for screening and rating contact sensitizers. , 1989, The Journal of investigative dermatology.

[94]  A. Fisher.  Sensitization to nickel from stainless steel ear‐piercing kits , 1994, Contact dermatitis.

[95]  E. Zimerson,et al.  Shoe contact dermatitis from dimethyl fumarate: clinical manifestations, patch test results, chemical analysis, and source of exposure , 2009, Contact dermatitis.

[96]  T. Reunala,et al.  Measurement of natural rubber latex allergen levels in medical gloves by allergen‐specific IgE‐ELISA inhibition, RAST inhibition, and skin prick test , 1998, Allergy.

[97]  S. Cupferman,et al.  Experimental elicitation of contact allergy from a diazolidinyl urea‐preserved cream in relation to anatomical region, exposure time and concentration , 2005, Contact dermatitis.

[98]  F. Marzulli,et al.  Risk assessment of the allergic dermatitis potential of environmental exposure to hexavalent chromium. , 1993, Journal of toxicology and environmental health.

[99]  H. Lessmann,et al.  When should a substance be designated as sensitizing for the skin (`Sh’) or for the airways (`Sa’)? , 2002, Pneumologie.

[100]  M. Lind,et al.  Permeability of hair dye compounds p-phenylenediamine, toluene-2,5-diaminesulfate and resorcinol through protective gloves in hairdressing. , 2007, The Annals of occupational hygiene.

[101]  P. Frosch,et al.  Hydroxyisohexyl 3‐cyclohexene carboxaldehyde‐ known as Lyral®: quantitative aspects and risk assessment of an important fragrance allergen , 2003, Contact dermatitis.

[102]  I Kimber,et al.  Skin sensitization risk assessment: a comparative evaluation of 3 isothiazolinone biocides , 1999, Contact dermatitis.

[103]  A. Tosti,et al.  Provocative use testing of methyldibromo glutaronitrile in a cosmetic shampoo , 2000, Contact dermatitis.

[104]  C. Nieboer,et al.  The risk of sensibilization and contact urticaria upon topical application of fumaric acid derivatives. , 1994, Dermatology.

[105]  S Z Mansdorf,et al.  Chemical protective clothing standard test method development. Part 1. Penetration test method. , 1988, American Industrial Hygiene Association journal.

[106]  M. Beylot-Barry,et al.  [Chinese chair dermatitis: a new form of contact dermatitis]. , 2008, Annales de dermatologie et de venereologie.

[107]  T. Bruening,et al.  The German experience 10 years after the latex allergy epidemic: need for further preventive measures in healthcare employees with latex allergy , 2010, International archives of occupational and environmental health.

[108]  A. Cristaudo,et al.  Contact sensitivity to hair dyes can be detected by the consumer open test. , 2002, European journal of dermatology : EJD.

[109]  P. Frosch,et al.  Clinical standardization of the TRUE Test formaldehyde patch. , 1995, Current problems in dermatology.

[110]  Frank Gerberick,et al.  Predictive identification of human skin sensitization thresholds , 2005, Contact dermatitis.

[111]  K. Peltonen,et al.  The permeability of surgical gloves to seven chemicals commonly used in hospitals. , 2003, The Annals of occupational hygiene.

[112]  H. Maibach,et al.  The use of graded concentrations in studying skin sensitizers: experimental contact sensitization in man. , 1974, Food and cosmetics toxicology.

[113]  B. Gruvberger,et al.  Sensitization studies in the guinea pig with the active ingredients of Euxyl® K 400 , 1988, Contact dermatitis.

[114]  C. Lidén.  Nickel in jewellery and associated products , 1992, Contact dermatitis.

[115]  S. Fregert,et al.  Contact urticaria from natural latex gloves , 1984, Contact dermatitis.

[116]  G. Angelini,et al.  Contact allergy to Kathon® CG , 1987, Contact dermatitis.

[117]  B. Gruvberger,et al.  In vivo testing of the protection provided by non-latex gloves against a 2-hydroxyethyl methacrylate-containing acetone-based dentin-bonding product. , 2000, Acta dermato-venereologica.

[118]  H. Lessmann,et al.  Designation of substances as skin sensitizing chemicals: a reply , 2005, Human & experimental toxicology.

[119]  J. Johansen,et al.  Dose per unit area – a study of elicitation of nickel allergy , 2007, Contact Dermatitis.

[120]  H Kromhout,et al.  Conceptual model for assessment of dermal exposure. , 1999, Occupational and environmental medicine.

[121]  J L Bonsall,et al.  The application of test data in the selection and use of gloves against chemicals. , 1990, The Annals of occupational hygiene.

[122]  S. Fregert,et al.  Reduction of chromate in cement by iron sulfate , 1979, Contact dermatitis.

[123]  J Hilton,et al.  Assessment of the relative skin sensitizing potency of 3 biocides using the murine local lymph node assay , 1991, Contact dermatitis.

[124]  J. Johansen,et al.  Reduction in the frequency of sensitization to thiurams. A result of legislation? , 2006, Contact dermatitis.

[125]  S. Fregert,et al.  Nickel release from ear piercing kits and earrings , 1984, Contact dermatitis.

[126]  D. Basketter,et al.  Designation of substances as skin sensitizing chemicals: a commentary , 2003, Human & experimental toxicology.

[127]  I. E. Ruyter,et al.  Permeability of Medical Gloves to Mono- and Dimethacrylate Monomers in Dental Restorative Materials , 2002, International journal of occupational safety and ergonomics : JOSE.

[128]  T. Reunala,et al.  Allergens in latex surgical gloves and glove powder , 1990, The Lancet.

[129]  B. Hausen.  The sensitizing potency of Euxyl® K 400 and its components 1,2‐dibromo‐2,4‐dicyanobutane and 2‐phenoxyethanol , 1993, Contact dermatitis.

[130]  D. Belsito,et al.  Dermatological Toxicity of Hexavalent Chromium , 2007, Critical reviews in toxicology.

[131]  J. W. Weyland,et al.  Patch test reactivity to DMDM hydantoin. Relationship to formaldehyde allergy. , 1988, Contact dermatitis.

[132]  A. Tosti,et al.  Euxyl K 400: a new sensitizer in cosmetics , 1991, Contact dermatitis.

[133]  Paul T. Bailey,et al.  Dose‐response assessments of Kathon® biocide (II) Threshold prophetic patch testing , 1986, Contact dermatitis.

[134]  B. Gruvberger,et al.  An outbreak of furniture related dermatitis (‘sofa dermatitis’) in Finland and the UK: history and clinical cases , 2010, Journal of the European Academy of Dermatology and Venereology : JEADV.

[135]  B. Gruvberger,et al.  Occupational allergic contact dermatitis due to methylisothiazolinones in a cleansing cream , 1990, Contact dermatitis.

[136]  F. Larese Filon,et al.  Latex allergy: a follow up study of 1040 healthcare workers , 2006, Occupational and Environmental Medicine.

[137]  Torkil Menné,et al.  Contact allergy epidemics and their controls * , 2007, Contact dermatitis.

[138]  K Schneider,et al.  Quantitative relationship between the local lymph node assay and human skin sensitization assays. , 2004, Regulatory toxicology and pharmacology : RTP.

[139]  L. Barregard,et al.  On permeability of methyl methacrylate, 2-hydroxyethyl methacrylate and triethyleneglycol dimethacrylate through protective gloves in dentistry. , 2003, European journal of oral sciences.