The Unique Domain Forms a Fuzzy Intramolecular Complex in Src Family Kinases.
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P. Bernadó | M. Pons | T. Cordeiro | Yolanda Pérez | S. Roche | Miguel Arbesú | M. Maffei | J. C. Teixeira
[1] Márton Miskei,et al. FuzDB: database of fuzzy complexes, a tool to develop stochastic structure-function relationships for protein complexes and higher-order assemblies , 2016, Nucleic Acids Res..
[2] Wayne Boucher,et al. CcpNmr AnalysisAssign: a flexible platform for integrated NMR analysis , 2016, Journal of Biomolecular NMR.
[3] Monika Fuxreiter,et al. The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules , 2016, Cell.
[4] C. Leroy,et al. YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells. , 2015, American journal of cancer research.
[5] M. Pons,et al. The SH3 Domain Acts as a Scaffold for the N-Terminal Intrinsically Disordered Regions of c-Src. , 2015, Structure.
[6] H. Dyson,et al. Intrinsically disordered proteins in cellular signalling and regulation , 2014, Nature Reviews Molecular Cell Biology.
[7] J. Jumper,et al. Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations , 2014, Proceedings of the National Academy of Sciences.
[8] V. Uversky. Intrinsically Disordered Proteins , 2014, SpringerBriefs in Molecular Science.
[9] M. Pons,et al. Phosphorylation of unique domains of Src family kinases , 2014, Front. Genet..
[10] V. Hilser,et al. The ensemble nature of allostery , 2014, Nature.
[11] M. Pons,et al. Lipid Binding by Disordered Proteins , 2013 .
[12] D. Baker,et al. Assessing the utility of coevolution-based residue–residue contact predictions in a sequence- and structure-rich era , 2013, Proceedings of the National Academy of Sciences.
[13] M. Gairí,et al. Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism , 2013, Scientific Reports.
[14] A. Hill,et al. A Truncated Fragment of Src Protein Kinase Generated by Calpain-mediated Cleavage Is a Mediator of Neuronal Death in Excitotoxicity* , 2013, The Journal of Biological Chemistry.
[15] Céline Charavay,et al. Flexible-meccano: a tool for the generation of explicit ensemble descriptions of intrinsically disordered proteins and their associated experimental observables , 2012, Bioinform..
[16] A. Biegert,et al. HHblits: lightning-fast iterative protein sequence searching by HMM-HMM alignment , 2011, Nature Methods.
[17] Frauke Gräter,et al. How sequence determines elasticity of disordered proteins. , 2010, Biophysical journal.
[18] Miquel Pons,et al. Structural characterization of the natively unfolded N-terminal domain of human c-Src kinase: insights into the role of phosphorylation of the unique domain. , 2009, Journal of molecular biology.
[19] G. Clore,et al. Theory, practice, and applications of paramagnetic relaxation enhancement for the characterization of transient low-population states of biological macromolecules and their complexes. , 2009, Chemical reviews.
[20] Cédric Leroy,et al. Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells. , 2009, Cancer research.
[21] M. Vargas-Caballero,et al. Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex , 2008, Nature Medicine.
[22] Carsten Kutzner,et al. GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation. , 2008, Journal of chemical theory and computation.
[23] A. Boureux,et al. The tyrosine kinase Abl is required for Src-transforming activity in mouse fibroblasts and human breast cancer cells , 2007, Oncogene.
[24] M. Blackledge,et al. Structural characterization of flexible proteins using small-angle X-ray scattering. , 2007, Journal of the American Chemical Society.
[25] Paul Schanda,et al. SOFAST-HMQC Experiments for Recording Two-dimensional Deteronuclear Correlation Spectra of Proteins within a Few Seconds , 2005, Journal of biomolecular NMR.
[26] Wayne Boucher,et al. The CCPN data model for NMR spectroscopy: Development of a software pipeline , 2005, Proteins.
[27] P. Stork,et al. PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells , 2004, Journal of Cell Science.
[28] T. Boggon,et al. Structure and regulation of Src family kinases , 2004, Oncogene.
[29] Robin S. Dothager,et al. Random-coil behavior and the dimensions of chemically unfolded proteins. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[30] Timothy J. Yeatman,et al. A renaissance for SRC , 2004, Nature Reviews Cancer.
[31] Eran Eyal,et al. Importance of solvent accessibility and contact surfaces in modeling side‐chain conformations in proteins , 2004, J. Comput. Chem..
[32] Robert C. Edgar,et al. MUSCLE: multiple sequence alignment with high accuracy and high throughput. , 2004, Nucleic acids research.
[33] D. Baker,et al. Design of a Novel Globular Protein Fold with Atomic-Level Accuracy , 2003, Science.
[34] Dmitri I. Svergun,et al. PRIMUS: a Windows PC-based system for small-angle scattering data analysis , 2003 .
[35] S. Blacklow,et al. A Zinc Clasp Structure Tethers Lck to T Cell Coreceptors CD4 and CD8 , 2003, Science.
[36] D. Mojzita,et al. The SH3 domain of Src can downregulate its kinase activity in the absence of the SH2 domain-pY527 interaction. , 2002, Biochemical and biophysical research communications.
[37] M. Gerstein,et al. Annotation Transfer for Genomics: Measuring Functional Divergence in Multi-Domain Proteins , 2001, Genome Research.
[38] P. Auberger,et al. Cleavage of Fyn and Lyn in their N-terminal unique regions during induction of apoptosis: a new mechanism for Src kinase regulation , 2001, Oncogene.
[39] N. Hynes,et al. Tyrosine kinase signalling in breast cancer , 2000, Breast Cancer Research.
[40] S. Harrison,et al. Crystal structures of c-Src reveal features of its autoinhibitory mechanism. , 1999, Molecular cell.
[41] D. Svergun,et al. CRYSOL : a program to evaluate X-ray solution scattering of biological macromolecules from atomic coordinates , 1995 .
[42] M. Resh,et al. Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[43] H. Vogel,et al. Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice. , 1994, Genes & development.
[44] J. DiPaolo,et al. Isolation and chromosomal localization of the human fgr protooncogene, a distinct member of the tyrosine kinase gene family. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[45] A. Sirvent,et al. Oncogenic signaling by tyrosine kinases of the SRC family in advanced colorectal cancer. , 2012, American journal of cancer research.
[46] P. Tompa,et al. Fuzzy complexes: polymorphism and structural disorder in protein-protein interactions. , 2008, Trends in biochemical sciences.
[47] Sheila M. Thomas,et al. Cellular functions regulated by Src family kinases. , 1997, Annual review of cell and developmental biology.