Rebamipide Suppresses Monosodium Urate Crystal-Induced Interleukin-1β Production Through Regulation of Oxidative Stress and Caspase-1 in THP-1 Cells

[1]  G. Yen,et al.  Monosodium urate crystals trigger Nrf2- and heme oxygenase-1-dependent inflammation in THP-1 cells , 2014, Cellular and Molecular Immunology.

[2]  J. Choe,et al.  Enhanced p62 expression through impaired proteasomal degradation is involved in caspase-1 activation in monosodium urate crystal-induced interleukin-1b expression. , 2014, Rheumatology.

[3]  J. Jeong,et al.  Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes. , 2012, Osteoarthritis and cartilage.

[4]  J. Tschopp,et al.  A role for mitochondria in NLRP3 inflammasome activation , 2011, Nature.

[5]  J. Choe,et al.  Rebamipide inhibits tumor necrosis factor-α-induced interleukin-8 expression by suppressing the NF-κB signal pathway in human umbilical vein endothelial cells , 2010, Inflammation Research.

[6]  A. So,et al.  Gout. Mechanisms of inflammation in gout , 2010, Arthritis research & therapy.

[7]  J. Tschopp,et al.  Thioredoxin-interacting protein links oxidative stress to inflammasome activation , 2010, Nature Immunology.

[8]  F. Martinon.  Mechanisms of uric acid crystal‐mediated autoinflammation , 2010, Immunological reviews.

[9]  M. Takei,et al.  Efficacy and safety of rebamipide for the treatment of dry mouth symptoms in patients with Sjögren’s syndrome: a double-blind placebo-controlled multicenter trial , 2009, Modern rheumatology.

[10]  Eun-So Lee,et al.  Rebamipide affects the efficiency of colchicine for the herpes simplex virus-induced inflammation in a Behcet's disease mouse model. , 2008, European journal of pharmacology.

[11]  N. Ishimaru,et al.  Effective treatment with oral administration of rebamipide in a mouse model of Sjögren's syndrome. , 2008, Arthritis and rheumatism.

[12]  Rhian M. Touyz,et al.  NADPH Oxidases, Reactive Oxygen Species, and Hypertension , 2008, Diabetes Care.

[13]  T. Nakagawa,et al.  Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress. , 2007, American journal of physiology. Cell physiology.

[14]  J. Tschopp,et al.  A pilot study of IL-1 inhibition by anakinra in acute gout , 2007, Arthritis research & therapy.

[15]  F. Martinon,et al.  Gout-associated uric acid crystals activate the NALP3 inflammasome , 2006, Nature.

[16]  R. Terkeltaub,et al.  TLR2 Signaling in Chondrocytes Drives Calcium Pyrophosphate Dihydrate and Monosodium Urate Crystal-Induced Nitric Oxide Generation1 , 2005, The Journal of Immunology.

[17]  M. Olivier,et al.  Signaling Events Involved in Macrophage Chemokine Expression in Response to Monosodium Urate Crystals* , 2004, Journal of Biological Chemistry.

[18]  James E. Evans,et al.  Molecular identification of a danger signal that alerts the immune system to dying cells , 2003, Nature.

[19]  M. Gerstein,et al.  Comparing protein abundance and mRNA expression levels on a genomic scale , 2003, Genome Biology.

[20]  Henry Jay Forman,et al.  Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling. , 2002, American journal of respiratory and critical care medicine.

[21]  A. Keshavarzian,et al.  Modulatory Effects of Plasma and Colonic Milieu of Patients with Ulcerative Colitis on Neutrophil Reactive Oxygen Species Production in Presence of a Novel Antioxidant, Rebamipide , 2002, Digestive Diseases and Sciences.

[22]  S. Bourgoin,et al.  Crystal‐induced neutrophil activation. VII. Involvement of Syk in the responses to monosodium urate crystals , 2001, Journal of leukocyte biology.

[23]  Hyeyoung Kim,et al.  Inhibition of Lipid Peroxidation, NF-κB Activation and IL-8 Production by Rebamipide in Helicobacter pylori-Stimulated Gastric Epithelial Cells , 2000, Digestive Diseases and Sciences.

[24]  A. Tarnawski,et al.  Rebamipide: overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing. , 1998, Digestive diseases and sciences.

[25]  G. Weissmann,et al.  Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils. , 1995, The Journal of clinical investigation.

[26]  F. Jamar,et al.  Noninvasive imaging of E-selectin expression by activated endothelium in urate crystal-induced arthritis. , 1994, Arthritis and rheumatism.

[27]  J. Hiscott,et al.  Characterization of a functional NF-kappa B site in the human interleukin 1 beta promoter: evidence for a positive autoregulatory loop , 1993, Molecular and cellular biology.

[28]  R. Terkeltaub,et al.  Monocyte-derived neutrophil chemotactic factor/interleukin-8 is a potential mediator of crystal-induced inflammation. , 1991, Arthritis and rheumatism.

[29]  P. Cameron,et al.  Identification of a monocyte specific pre-interleukin 1 beta convertase activity. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[30]  R. Black,et al.  Activation of interleukin‐ 1β by a co‐induced protease , 1989 .

[31]  J. Choe,et al.  Oxidative stress by monosodium urate crystals promotes renal cell apoptosis through mitochondrial caspase-dependent pathway in human embryonic kidney 293 cells: mechanism for urate-induced nephropathy , 2014, Apoptosis.

[32]  P. Kubes,et al.  Monosodium urate crystals promote neutrophil adhesion via a CD18-independent and selectin-independent mechanism. , 1996, The American journal of physiology.

[33]  M P Bevilacqua,et al.  Endothelial-leukocyte adhesion molecules. , 1993, Annual review of immunology.

[34]  R. Black,et al.  Activation of interleukin-1 beta by a co-induced protease. , 1989, FEBS letters.

[35]  A. Ryckewaert.  [Pathogenesis of gout]. , 1966, Revue francaise d'etudes cliniques et biologiques.