Sinonasal Polyposis and Fungus:A Growing Relationship

OBJECTIVES: To determine the frequency of underlying fungus in nose and paranasal sinuses in patients present with nasal polyposis. METHODOLOGY: A total of 324 patients presented with nasal polyps were included in this study. Data collected from all the patients admitted in ENT department with diagnosis of nasal polyposis. All the relevant information about their presenting symptoms was recorded in a proforma. Post operatively the removed material was sent for histopathology and fungal culture. Later the findings of biopsy and culture reports were also recorded and analysed. RESULTS: Out of 324 patients 159 were males and 165 were females. Underlying fungus was present in 226(69.75%) and out of them, 102(45.13%) were males and 124(54.86%) were females with a P value of 0.039. The mean age was 25.95 ± 9.32 (15-45) years for the patient with fungus. Aspergillus was the commonest organism found. CONCLUSION: Underlying fungus was found in a significantly high number of patients presented with nasal polyps and Aspergillus was the commonest organism found.

[1]  Shukla Das,et al.  Frequency of fungal isolation and antifungal susceptibility pattern of the fungal isolates from nasal polyps of chronic rhinosinusitis patients at a tertiary care centre in north India. , 2013, Medical mycology.

[2]  M. Jawaid,et al.  Allergic fungal rhinosinusitis with skull base and orbital erosion. , 2010, The Journal of laryngology and otology.

[3]  F. Lee,et al.  Incidence of Skull Base and Orbital Erosion in Allergic Fungal Rhinosinusitis (AFRS) and Non-AFRS , 2006, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[4]  P. Hwang,et al.  The office management of recalcitrant rhinosinusitis. , 2004, Otolaryngologic clinics of North America.

[5]  N. Bikhazi.  Contemporary management of nasal polyps. , 2004, Otolaryngologic clinics of North America.

[6]  S. Ghosh,et al.  Sinonasal aspergillosis in immunocompetent Indian children: an eight‐year experience , 2003, Mycoses.

[7]  N. Bateman,et al.  Nasal polyps: Still more questions than answers , 2003, The Journal of Laryngology & Otology.

[8]  S. Chandi,et al.  Clinicopathological and mycological spectrum of allergic fungal sinusitis in South India , 2002, Mycoses.

[9]  M. S. Schubert,et al.  Fungal rhinosinusitis: Diagnosis and therapy , 2001, Current allergy and asthma reports.

[10]  M. S. Schubert,et al.  Medical treatment of allergic fungal sinusitis. , 2000, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[11]  N. Uri,et al.  Classification of Fungal Sinusitis in Immunocompetent Patients , 1999, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[12]  S. Schaefer,et al.  Clinical Evaluation of Rhinosinusitis: History and Physical Examination , 1997, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[13]  G. Philip,et al.  Allergic fungal sinusitis , 1989 .

[14]  M. Delos,et al.  Mycotic sinusitis. , 1997, Acta oto-rhino-laryngologica Belgica.

[15]  M. Oermann,et al.  [Clinical evaluation]. , 1981, Ugeskrift for laeger.

[16]  R. Harvey,et al.  Nasal polyposis: an inflammatory condition requiring effective anti-inflammatory treatment , 2013, Current opinion in otolaryngology & head and neck surgery.