Supra Renal Biological Lateralization in Albino Rats

In order to shade light on adrenal biological lateralization and its relation to age, sex, stressful condition and circadian rhythm, the present work was done on 12 groups of rats of both sexes (6 rats in each). These groups were classified according to age (young and adults), sex, condition (non-stress and cold restraint stress) and time of the day (9 am and 9 pm). All animals were anaethetized, dissected to get suprarenal gland onboth sidesout of the abdomen. The glands were weighted, their catecholamines and serotonin were determined by using the spectrofluorophotometer. The results revealed a significant left lateralization of the gland weight and with right lateralization of its hormones in adult rats. Stress did not affect this lateralization. Also, the results showed a significant suprarenal medullary hormones lateralization in female rats compared with the male ones, with circadian lateralization of adult female rats. Data of the present study will open the door for further study, research and investigation about the role of supra-renal biological lateralization on stress developing disease, the role of supra-renal biological lateralization on age & sex related response to stress and also, circadian relation to stress response.

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