White matter inflammation and cognitive function in a co-morbid metabolic syndrome and prodromal Alzheimer’s disease rat model

[1]  Meray Serdar,et al.  Early Pro-inflammatory Microglia Activation After Inflammation-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Rats , 2019, Front. Cell. Neurosci..

[2]  Takahiro A. Kato,et al.  Suicide and Microglia: Recent Findings and Future Perspectives Based on Human Studies , 2019, Front. Cell. Neurosci..

[3]  V. Hachinski,et al.  APP21 transgenic rats develop age-dependent cognitive impairment and microglia accumulation within white matter tracts , 2018, Journal of Neuroinflammation.

[4]  H. Weiner,et al.  Pro‐inflammatory activation of microglia in the brain of patients with sepsis , 2018, Neuropathology and applied neurobiology.

[5]  T. Schachtman,et al.  Memory deficiency, cerebral amyloid angiopathy, and amyloid-β plaques in APP+PS1 double transgenic rat model of Alzheimer’s disease , 2018, PloS one.

[6]  R. Crnjar,et al.  Effect of chemical interaction between oleic acid and L-Arginine on oral perception, as a function of polymorphisms of CD36 and OBPIIa and genetic ability to taste 6-n-propylthiouracil , 2018, PloS one.

[7]  Patrick O. McGowan,et al.  Epigenetic impacts of stress priming of the neuroinflammatory response to sarin surrogate in mice: a model of Gulf War illness , 2018, Journal of Neuroinflammation.

[8]  M. Saklayen.  The Global Epidemic of the Metabolic Syndrome , 2018, Current Hypertension Reports.

[9]  L. Polgreen,et al.  Team-Based Care with Pharmacists to Improve Blood Pressure: a Review of Recent Literature , 2018, Current Hypertension Reports.

[10]  W. D. den Dunnen,et al.  Increased White Matter Inflammation in Aging- and Alzheimer’s Disease Brain , 2017, Front. Mol. Neurosci..

[11]  Bo Bai,et al.  Temporal Expression of Apelin/Apelin Receptor in Ischemic Stroke and its Therapeutic Potential , 2017, Front. Mol. Neurosci..

[12]  D. Corbett,et al.  A physiological characterization of the Cafeteria diet model of metabolic syndrome in the rat , 2016, Physiology & Behavior.

[13]  John C Rutledge,et al.  Metabolic, inflammatory, and microvascular determinants of white matter disease and cognitive decline. , 2016, American journal of neurodegenerative disease.

[14]  B. Stoica,et al.  Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury. , 2016, Journal of neurotrauma.

[15]  S. Rivest,et al.  High fat diet exacerbates Alzheimer's disease-related pathology in APPswe/PS1 mice , 2016, Oncotarget.

[16]  Jiunn‐Tay Lee,et al.  Increased risk of cognitive impairment in patients with components of metabolic syndrome , 2016, Medicine.

[17]  Yu Hasegawa,et al.  High‐Fat‐Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic Disorders , 2016, Journal of the American Heart Association.

[18]  Nick C Fox,et al.  White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network , 2016, Annals of neurology.

[19]  L. C. Antunes,et al.  Validation of HOMA-IR in a model of insulin-resistance induced by a high-fat diet in Wistar rats. , 2016, Archives of endocrinology and metabolism.

[20]  W. Le,et al.  Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases , 2016, Molecular Neurobiology.

[21]  Timothy S. Phan,et al.  Misinterpretation of the Determinants of Elevated Forward Wave Amplitude Inflates the Role of the Proximal Aorta , 2016, Journal of the American Heart Association.

[22]  M. Silvestrini,et al.  Metabolic syndrome and cerebrovascular impairment in Alzheimer's disease , 2015, International journal of geriatric psychiatry.

[23]  Burkhard Becher,et al.  Immune attack: the role of inflammation in Alzheimer disease , 2015, Nature Reviews Neuroscience.

[24]  P. Scheltens,et al.  White matter hyperintensities, cognitive impairment and dementia: an update , 2015, Nature Reviews Neurology.

[25]  A. Brickman,et al.  Reconsidering harbingers of dementia: progression of parietal lobe white matter hyperintensities predicts Alzheimer's disease incidence , 2015, Neurobiology of Aging.

[26]  A. Killcross,et al.  Obesity and cognitive decline: role of inflammation and vascular changes , 2014, Front. Neurosci..

[27]  S. Allan,et al.  High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology , 2014, Neurobiology of Aging.

[28]  Daniel S. Margulies,et al.  Prioritizing spatial accuracy in high-resolution fMRI data using multivariate feature weight mapping , 2014, Front. Neurosci..

[29]  C. Pike,et al.  Alzheimer’s Disease and Type 2 Diabetes: Multiple Mechanisms Contribute to Interactions , 2014, Current Diabetes Reports.

[30]  P. Agostinho,et al.  Spatial memory impairments in a prediabetic rat model , 2013, Neuroscience.

[31]  E. Blalock,et al.  Effect of high-fat diet on metabolic indices, cognition, and neuronal physiology in aging F344 rats , 2013, Neurobiology of Aging.

[32]  Alexander Leemans,et al.  Disruption of the Cerebral White Matter Network Is Related to Slowing of Information Processing Speed in Patients With Type 2 Diabetes , 2013, Diabetes.

[33]  J. Leszek,et al.  Metabolic syndrome, mild cognitive impairment and Alzheimer's disease—The emerging role of systemic low-grade inflammation and adiposity , 2012, Brain Research Bulletin.

[34]  R. Leak,et al.  Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia , 2012, Stroke.

[35]  C. Filley,et al.  White matter dementia , 2012, Therapeutic advances in neurological disorders.

[36]  J. Lah,et al.  Exogenous seeding of cerebral β‐amyloid deposition in βAPP‐transgenic rats , 2012, Journal of neurochemistry.

[37]  F. Panza,et al.  Metabolic syndrome, mild cognitive impairment, and dementia. , 2011, Current Alzheimer research.

[38]  A. Granholm,et al.  Diet-induced effects on neuronal and glial elements in the middle-aged rat hippocampus , 2011, Nutritional neuroscience.

[39]  N. Bhat.  Linking cardiometabolic disorders to sporadic Alzheimer’s disease: a perspective on potential mechanisms and mediators , 2010, Journal of neurochemistry.

[40]  Daniele Sancarlo,et al.  Metabolic-cognitive syndrome: A cross-talk between metabolic syndrome and Alzheimer's disease , 2010, Ageing Research Reviews.

[41]  B. Winblad,et al.  Hypoglycemia in Alzheimer's disease. , 2009, Acta medica Scandinavica.

[42]  Susanna Sallstroem,et al.  Functional Differentiation , 2009, Modern Condensed Matter Physics.

[43]  C. Cao,et al.  The potential of hematopoietic growth factors for treatment of Alzheimer's disease: a mini-review , 2008, BMC Neuroscience.

[44]  Jeffrey A. James,et al.  Frequent amyloid deposition without significant cognitive impairment among the elderly. , 2008, Archives of neurology.

[45]  G. Pasinetti,et al.  Metabolic syndrome and the role of dietary lifestyles in Alzheimer’s disease , 2008, Journal of neurochemistry.

[46]  V. Hachinski,et al.  Vascular risk factors and Alzheimer’s disease , 2008, Expert review of neurotherapeutics.

[47]  A. Levey,et al.  Development of transgenic rats producing human β-amyloid precursor protein as a model for Alzheimer's disease: Transgene and endogenous APP genes are regulated tissue-specifically , 2008, BMC Neuroscience.

[48]  J. O'Brien,et al.  Microglial activation in white matter lesions and nonlesional white matter of ageing brains , 2007, Neuropathology and applied neurobiology.

[49]  J. O'Brien,et al.  White matter lesions in an unselected cohort of the elderly: astrocytic, microglial and oligodendrocyte precursor cell responses , 2007, Neuropathology and applied neurobiology.

[50]  M. Laakso,et al.  Association of metabolic syndrome with Alzheimer disease , 2006, Neurology.

[51]  V. Haroutunian,et al.  Microglia Activation in the Brain as Inflammatory Biomarker of Alzheimer’s Disease Neuropathology and Clinical Dementia , 2005, Disease markers.

[52]  Hilkka Soininen,et al.  Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. , 2005, Archives of neurology.

[53]  Kristine Yaffe,et al.  Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study , 2005, BMJ : British Medical Journal.

[54]  Neil Mann,et al.  Origins and evolution of the Western diet: health implications for the 21st century. , 2005, The American journal of clinical nutrition.

[55]  J. Feldon,et al.  Dissociation of function between the dorsal and the ventral hippocampus in spatial learning abilities of the rat: a within‐subject, within‐task comparison of reference and working spatial memory , 2004, The European journal of neuroscience.

[56]  F. Gomez-Pinilla,et al.  A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning , 2002, Neuroscience.

[57]  F. Schmitt,et al.  Alzheimer neuropathologic alterations in aged cognitively normal subjects. , 1999, Journal of neuropathology and experimental neurology.

[58]  S. Tonegawa,et al.  The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory , 1996, Cell.

[59]  A Brun,et al.  White matter changes in dementia of Alzheimer's type: the difference in vulnerability between cell compartments , 1990, Histopathology.

[60]  Miguel Alaminos,et al.  Staining Methods for Normal and Regenerative Myelin in the Nervous System. , 2017, Methods in molecular biology.

[61]  Christos Davatzikos,et al.  Correlating Cognitive Decline with White Matter Lesion and Brain Atrophy Magnetic Resonance Imaging Measurements in Alzheimer's Disease. , 2015, Journal of Alzheimer's disease : JAD.

[62]  H. Soininen,et al.  Midlife vascular risk factors and Alzheimer's disease: evidence from epidemiological studies. , 2012, Journal of Alzheimer's disease : JAD.

[63]  F. LaFerla,et al.  Alzheimer's disease. , 2010, The New England journal of medicine.

[64]  Yanshu Zhang,et al.  The effects of a high-energy diet on hippocampal function and blood-brain barrier integrity in the rat. , 2010, Journal of Alzheimer's disease : JAD.

[65]  L. Tappy,et al.  Metabolic effects of fructose and the worldwide increase in obesity. , 2010, Physiological reviews.

[66]  A. Granholm,et al.  Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat. , 2008, Journal of Alzheimer's disease : JAD.

[67]  G. Wilcock,et al.  The metabolic syndrome and Alzheimer disease. , 2007, Archives of neurology.

[68]  H. Braak,et al.  Neuropathological stageing of Alzheimer-related changes , 2004, Acta Neuropathologica.

[69]  M. Moser,et al.  Functional differentiation in the hippocampus , 1998, Hippocampus.

[70]  G. Paxinos,et al.  The Rat Brain in Stereotaxic Coordinates , 1983 .