Merkel cell polyomavirus T-antigen-mediated reprogramming in adult Merkel cell progenitors.

[1]  G. Sauter,et al.  Cytokeratin 10 (CK10) expression in cancer: A tissue microarray study on 11,021 tumors. , 2022, Annals of diagnostic pathology.

[2]  Michael C. Kelly,et al.  Direct cellular reprogramming enables development of viral T antigen–driven Merkel cell carcinoma in mice , 2022, The Journal of clinical investigation.

[3]  Kervarrec Thibault.  Evidence of an epithelial origin of Merkel cell carcinoma , 2021, Modern Pathology.

[4]  V. Koljonen,et al.  LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers , 2021, Virchows Archiv.

[5]  R. Gutiérrez,et al.  Cd34+ Stromal Cells/Telocytes in Normal and Pathological Skin , 2021, International journal of molecular sciences.

[6]  C. Destrieux,et al.  Merkel Cell Polyomavirus T Antigens Induce Merkel Cell-Like Differentiation in GLI1-Expressing Epithelial Cells , 2020, Cancers.

[7]  M. Washburn,et al.  Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis , 2020, Nature Cell Biology.

[8]  N. Sopko,et al.  The applied anatomy of human skin: A model for regeneration , 2020 .

[9]  D. Schrama,et al.  Polyomavirus-positive Merkel cell carcinoma derived from a trichoblastoma suggests an epithelial origin of this Merkel cell carcinoma. , 2019, The Journal of investigative dermatology.

[10]  J. Becker,et al.  Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibition , 2019, Proceedings of the National Academy of Sciences.

[11]  E. Blanchard,et al.  Histogenesis of Merkel Cell Carcinoma: A Comprehensive Review , 2019, Front. Oncol..

[12]  L. Cinel,et al.  A new immunohistochemical marker, insulinoma-associated protein 1 (INSM1), for Merkel cell carcinoma: Evaluation of 24 cases. , 2019, Annals of diagnostic pathology.

[13]  D. Zheng,et al.  Dissection of Merkel cell formation in hairy and glabrous skin reveals a common requirement for FGFR2‐mediated signalling , 2019, Experimental dermatology.

[14]  J. Cobo,et al.  Ageing of the somatosensory system at the periphery: age‐related changes in cutaneous mechanoreceptors , 2019, Journal of anatomy.

[15]  Reety Arora,et al.  MCV Truncated Large T antigen interacts with BRD4 in tumors. , 2019, Matters.

[16]  Jingwei Cheng,et al.  Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response , 2018, Proceedings of the National Academy of Sciences.

[17]  F. Aubin,et al.  Diagnostic accuracy of a panel of immunohistochemical and molecular markers to distinguish Merkel cell carcinoma from other neuroendocrine carcinomas , 2018, Modern Pathology.

[18]  G. Freeman,et al.  LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade , 2018, Cell.

[19]  O. Klein,et al.  FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells , 2018, Nature Communications.

[20]  Hongzhen Hu,et al.  Piezo2 channel–Merkel cell signaling modulates the conversion of touch to itch , 2018, Science.

[21]  M. Rutland,et al.  Mechanisms of tactile sensory deterioration amongst the elderly , 2018, Scientific Reports.

[22]  R. Lloyd,et al.  Insulinoma‐associated 1: A novel nuclear marker in Merkel cell carcinoma (cutaneous neuroendocrine carcinoma) , 2018, Journal of cutaneous pathology.

[23]  J. North,et al.  Merkel cell carcinoma: An update and review: Pathogenesis, diagnosis, and staging. , 2017, Journal of the American Academy of Dermatology.

[24]  A. Stang,et al.  Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics , 2017, Journal of the American Academy of Dermatology.

[25]  Benjamin J. Strober,et al.  Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis , 2017, PLoS pathogens.

[26]  C. Bichakjian,et al.  Merkel Cell Polyomavirus Small T Antigen Initiates Merkel Cell Carcinoma-like Tumor Development in Mice. , 2017, Cancer research.

[27]  S. Maricich,et al.  Merkel cells are long-lived cells whose production is stimulated by skin injury. , 2017, Developmental biology.

[28]  Gregory J. Gerling,et al.  Touch Receptors Undergo Rapid Remodeling in Healthy Skin. , 2016, Cell reports.

[29]  F. Pontén,et al.  SATB2 is expressed in Merkel cell carcinoma , 2016, Archives of Dermatological Research.

[30]  S. Haferkamp,et al.  RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells , 2016, Oncotarget.

[31]  Takaaki Ito,et al.  Insulinoma-Associated Protein 1 Is a Crucial Regulator of Neuroendocrine Differentiation in Lung Cancer. , 2015, The American journal of pathology.

[32]  P. Moore,et al.  Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expression. , 2015, The Journal of general virology.

[33]  F. Jenkins,et al.  Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model , 2015, PloS one.

[34]  S. Maricich,et al.  Ectopic Atoh1 expression drives Merkel cell production in embryonic, postnatal and adult mouse epidermis , 2015, Development.

[35]  Ying Xiao,et al.  Neural Hedgehog signaling maintains stem cell renewal in the sensory touch dome epithelium , 2015, Proceedings of the National Academy of Sciences.

[36]  N. Ward,et al.  Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches. , 2015, Cell stem cell.

[37]  Jingwei Cheng,et al.  Tumorigenic activity of merkel cell polyomavirus T antigens expressed in the stratified epithelium of mice. , 2015, Cancer research.

[38]  M. Hoshino,et al.  Unipotent, Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice , 2015, The Journal of cell biology.

[39]  Ellen A Lumpkin,et al.  Merkel cells and neurons keep in touch. , 2015, Trends in cell biology.

[40]  A. Brunet,et al.  Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis. , 2015, Cell stem cell.

[41]  Francis J. Santoriello,et al.  Embryonic maturation of epidermal Merkel cells is controlled by a redundant transcription factor network , 2014, Development.

[42]  M. Imperiale,et al.  Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice , 2014, The Journal of investigative dermatology.

[43]  Andrew Macdonald,et al.  Merkel Cell Polyomavirus: Molecular Insights into the Most Recently Discovered Human Tumour Virus , 2014, Cancers.

[44]  E. Lumpkin,et al.  Diversification and specialization of touch receptors in skin. , 2014, Cold Spring Harbor perspectives in medicine.

[45]  Seung-Hyun Woo,et al.  The touch dome defines an epidermal niche specialized for mechanosensory signaling. , 2013, Cell reports.

[46]  Jeung-Hoon Lee,et al.  Expression and Functional Role of Sox9 in Human Epidermal Keratinocytes , 2013, PloS one.

[47]  I. Moll,et al.  Which Are the Cells of Origin in Merkel Cell Carcinoma? , 2012, Journal of skin cancer.

[48]  Xin Wang,et al.  Bromodomain Protein Brd4 Plays a Key Role in Merkel Cell Polyomavirus DNA Replication , 2012, PLoS pathogens.

[49]  Johannes P. W. Grimm,et al.  An intact retinoblastoma protein‐binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells , 2012, International journal of cancer.

[50]  Yuan Chang,et al.  Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator. , 2011, The Journal of clinical investigation.

[51]  H. Joensuu,et al.  Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell Carcinoma , 2011, Clinical Cancer Research.

[52]  Xi Liu,et al.  Merkel Cell Polyomavirus Large T Antigen Disrupts Lysosome Clustering by Translocating Human Vam6p from the Cytoplasm to the Nucleus , 2011, The Journal of Biological Chemistry.

[53]  A. Ferraz,et al.  In situ hybridization detection of homeobox genes reveals distinct expression patterns in oral squamous cell carcinomas , 2011, Histopathology.

[54]  Seung-Hyun Woo,et al.  Identification of epidermal progenitors for the Merkel cell lineage , 2010, Development.

[55]  A. Toland,et al.  Merkel cell polyomavirus in cutaneous squamous cell carcinoma of immunocompetent individuals. , 2009, The Journal of investigative dermatology.

[56]  E. Lumpkin,et al.  Mammalian Merkel cells are descended from the epidermal lineage. , 2009, Developmental biology.

[57]  Bassem A. Hassan,et al.  Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis , 2009, The Journal of cell biology.

[58]  J. Becker,et al.  Human Merkel cell polyomavirus infection II. MCV is a common human infection that can be detected by conformational capsid epitope immunoassays , 2009, International journal of cancer.

[59]  Ralf Paus,et al.  The Hair Follicle as a Dynamic Miniorgan , 2009, Current Biology.

[60]  Yuan Chang,et al.  T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus , 2008, Proceedings of the National Academy of Sciences.

[61]  P. Moore,et al.  Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma , 2008, Science.

[62]  Timothy J. Mitchison,et al.  A chemical method for fast and sensitive detection of DNA synthesis in vivo , 2008, Proceedings of the National Academy of Sciences.

[63]  C. Ross,et al.  TdT expression in Merkel cell carcinoma: potential diagnostic pitfall with blastic hematological malignancies and expanded immunohistochemical analysis , 2007, Modern Pathology.

[64]  A. Giordano,et al.  RB and cell cycle progression , 2006, Oncogene.

[65]  M. Iacocca,et al.  Mixed Merkel cell carcinoma and squamous cell carcinoma of the skin. , 1998, Journal of the American Academy of Dermatology.

[66]  R. Moll,et al.  Cytokeratin 20 is a general marker of cutaneous Merkel cells while certain neuronal proteins are absent. , 1995, The Journal of investigative dermatology.

[67]  U. Wollina,et al.  Epidermal Merkel cells in psoriatic lesions: immunohistochemical investigations on neuroendocrine antigen expression. , 1992, Journal of dermatological science.

[68]  J. Polak,et al.  Immunostaining of neuron‐specific enolase as a diagnostic tool for merkel cell tumors , 1983, Cancer.

[69]  C. Tang,et al.  Trabecular carcinoma of the skin: further clinicopathologic and ultrastructural study. , 1979, The Mount Sinai journal of medicine, New York.