Muscle relaxants in paediatric day case surgery

&NA; It has been estimated that more than 60% of all paediatric surgery is performed on a day case basis. The benefits of this type of surgery in children include reduced costs, avoidance of the stress of hospitalization and less disruption to family life. The growth of day surgery in children has been facilitated by the development of non‐depolarizing neuromuscular blocking agents characterized by short and intermediate duration of action and fewer side‐effects. The more rapid onset and shorter duration of action of nondepolarizing neuromuscular blocking agents in children should facilitate the use of these agents in place of succinylcholine for day case procedures.

[1]  M. Naguib How serious is the bronchospasm induced by rapacuronium? , 2001, Anesthesiology.

[2]  J. Lerman,et al.  Bronchospasm after rapacuronium in infants and children. , 2001, Anesthesiology.

[3]  N. Goudsouzian Rapacuronium and bronchospasm. , 2001, Anesthesiology.

[4]  S. Kron Severe bronchospasm and desaturation in a child associated with rapacuronium. , 2001, Anesthesiology.

[5]  B. Debaene,et al.  Rapacuronium 2.0 or 2.5 mg kg-1 for rapid-sequence induction: comparison with succinylcholine 1.0 mg kg-1. , 2000, British journal of anaesthesia.

[6]  T. Taivainen,et al.  The safety and efficacy of cisatracurium 0.15 mg.kg−1 during nitrous oxide–opioid anaesthesia in infants and children , 2000, Anaesthesia.

[7]  T. Taivainen,et al.  A Dose-ranging Study of Rapacuronium in Pediatric Patients , 2000, Anesthesiology.

[8]  A. Ross,et al.  Neuromuscular effects of rapacuronium in pediatric patients during nitrous oxide-halothane anesthesia: comparison with mivacurium , 2000, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[9]  Hannallah Rs,et al.  The potency (ED50) and cardiovascular effects of rapacuronium (Org 9487) during narcotic-nitrous oxide-propofol anesthesia in neonates, infants, and children. , 1999 .

[10]  M. Gordon,et al.  Dose response relationships for isobaric spinal mepivacaine using the combined spinal epidural technique. , 1999, Anesthesia and analgesia.

[11]  L. Brennan Modern day-case anaesthesia for children. , 1999, British journal of anaesthesia.

[12]  I. Hatcher,et al.  Postal survey of the anaesthetic techniques used for paediatric tonsillectomy surgery , 1999, Paediatric anaesthesia.

[13]  F. Donati,et al.  Early reversal of rapacuronium with neostigmine. , 1999, Anesthesiology.

[14]  J. Proost,et al.  Pharmacokinetics and pharmacokinetic-dynamic relationship between rapacuronium (Org 9487) and its 3-desacetyl metabolite (Org 9488). , 1999, Anesthesia and analgesia.

[15]  R. Kaplan,et al.  The potency (ED50) and cardiovascular effects of rapacuronium (Org 9487) during narcotic-nitrous oxide-propofol anesthesia in neonates, infants, and children. , 1999, Anesthesia and analgesia.

[16]  A. Ross,et al.  Onset and recovery of neuromuscular blockade after two doses of rocuronium in children. , 1998, Journal of clinical anesthesia.

[17]  A. Ross,et al.  Org 9487 or mivacurium in children anaesthetized with nitrous oxide-halothane: 57 , 1997 .

[18]  D. Jerwood,et al.  Routine suxamethonium in children , 1996, Anaesthesia.

[19]  G. Meakin,et al.  Dose—response and minimum time to satisfactory intubation conditions after mivacurium in children , 1996, Anaesthesia.

[20]  T. Taivainen,et al.  Pharmacodynamic effects of 51W89, an isomer of atracurium, in children during halothane anaesthesia. , 1995, British journal of anaesthesia.

[21]  T. Taivainen,et al.  Pharmacodynamics of mivacurium in infants. , 1994, British journal of anaesthesia.

[22]  J. Proost,et al.  Pharmacodynamics and pharmacokinetics of an infusion of Org 9487, a new short-acting steroidal neuromuscular blocking agent. , 1994, British journal of anaesthesia.

[23]  F. McGowan,et al.  Neuromuscular effects of 600 μg·kg−1 of rocuronium in infants during nitrous oxide‐halothane anaesthesia , 1994 .

[24]  F. McGowan,et al.  Clinical pharmacology of mivacurium in pediatric patients less than off years old during nitrous oxide-halothane anesthesia. , 1993, Anesthesia and analgesia.

[25]  K. Olkkola,et al.  Pharmacodynamics of mivacurium in children, using a computer-controlled infusion. , 1993, British journal of anaesthesia.

[26]  R. Mirakhur,et al.  Prolonged neuromuscular block following mivacurium. , 1993, Anesthesiology.

[27]  L. Casini,et al.  [The use of low doses of intermediate acting muscle relaxants in adenotonsillectomy]. , 1993, Minerva anestesiologica.

[28]  G. Gronert,et al.  Intractable cardiac arrest in children given succinylcholine. , 1992, Anesthesiology.

[29]  J. Apfelbaum Muscle relaxants for outpatient surgery: old and new. , 1992, Journal of clinical anesthesia.

[30]  D. R. Cook,et al.  Effects of bolus administration of ORG-9426 in children during nitrous oxide-halothane anesthesia. , 1992, Anesthesiology.

[31]  F. Donati,et al.  Postoperative Neuromuscular Function in Pediatric Day‐care Patients , 1991, Anesthesia and analgesia.

[32]  M. Reed,et al.  Intubation with Low‐Dose Atracurium in Children , 1989, Anesthesia and analgesia.

[33]  R. Welch,et al.  In Vitro Metabolism of Mivacurium Chloride (BW B1090U) and Succinylcholine , 1989, Anesthesia and analgesia.

[34]  B. Brandom,et al.  Clinical Pharmacology of Mivacurium Chloride (BW B1090U) in Children During Nitrous Oxide‐Halothane and Nitrous Oxide‐Narcotic Anesthesia , 1989, Anesthesia and analgesia.

[35]  O. Meretoja Is vecuronium a long-acting neuromuscular blocking agent in neonates and infants? , 1989, British journal of anaesthesia.

[36]  O. Meretoja,et al.  Duration of action of vecuronium in infants and children anaesthetized without potent inhalation agents , 1989, Acta anaesthesiologica Scandinavica.

[37]  W. Bowman,et al.  Structure: action Relationships Among Some Desacetoxy Analogues of Pancuronium and Vecuronium in the Anesthetized Cat , 1988, Anesthesiology.

[38]  G. Meakin,et al.  Comparison of atracurium-induced neuromuscular blockade in neonates, infants and children. , 1988, British journal of anaesthesia.

[39]  Ronald D. Miller,et al.  Vecuronium kinetics and dynamics in anesthetized infants and children , 1985, Clinical pharmacology and therapeutics.

[40]  H. H. Ali,et al.  Clinical Pharmacology of Atracurium Besylate (BW 33A): A New Non‐depolarizing Muscle Relaxant , 1982, Anesthesia and analgesia.

[41]  L. M. Liu,et al.  Dose response to intramuscular succinylcholine in children. , 1980, Anesthesiology.