论文信息 - GC-MS, HPLC, TLC of Dorycnium herbaceum Tincture Species and Synergistic / Antagonist Effect Testing in Combination with Antibiotics

GC-MS, HPLC, TLC of Dorycnium herbaceum Tincture Species and Synergistic / Antagonist Effect Testing in Combination with Antibiotics

The study objectives were to determine the chemical composition and the synergistic / antagonistic effect of the association between hydroalcoholic extract from the Dorycnii pentaphylli herba (DPH) and the antibiotics of choice, on five reference strains. The tincture contains flavonoids and polyphenol carboxylic acids in low concentrations. DPH has an antagonistic effect on three of the drugs tested (amoxicillin + clavulanic acid, levofloxacin, amikacin), the therapeutic effect being completely canceled and has no significant effect on two of them (ceftazidime, cefotaxime).

R. Văruţ | L. Rotaru

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