Genetic factors contribute to variation in serum alanine aminotransferase activity independent of obesity and alcohol: a study in monozygotic and dizygotic twins.

[1]  Hirokazu Takahashi,et al.  Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD) , 2008, BMC gastroenterology.

[2]  V. Wong,et al.  Genetic polymorphisms of adiponectin and tumor necrosis factor‐alpha and nonalcoholic fatty liver disease in Chinese people , 2008, Journal of gastroenterology and hepatology.

[3]  E. Ergul,et al.  Methylenetetrahydrofolate reductase gene polymorphisms in patients with nonalcoholic steatohepatitis (NASH) , 2008, Cell biochemistry and function.

[4]  Y. Hui,et al.  Effect of peroxisome proliferator‐activated receptors‐γ and co‐activator‐1α genetic polymorphisms on plasma adiponectin levels and susceptibility of non‐alcoholic fatty liver disease in Chinese people , 2007, Liver international : official journal of the International Association for the Study of the Liver.

[5]  A. Kotronen,et al.  Fatty Liver: A Novel Component of the Metabolic Syndrome , 2007, Arteriosclerosis, thrombosis, and vascular biology.

[6]  A. Kotronen,et al.  Effect of liver fat on insulin clearance. , 2007, American journal of physiology. Endocrinology and metabolism.

[7]  N. Martin,et al.  A Longitudinal Genetic Study of Uric Acid and Liver Enzymes in Adolescent Twins , 2007, Twin Research and Human Genetics.

[8]  K. Pietiläinen,et al.  Liver fat in the metabolic syndrome. , 2007, The Journal of clinical endocrinology and metabolism.

[9]  M. Taniai,et al.  Influence of TNF gene polymorphisms in Japanese patients with NASH and simple steatosis. , 2007, Journal of hepatology.

[10]  T. Saibara,et al.  The phosphatidylethanolamine N-methyltransferase gene V175M single nucleotide polymorphism confers the susceptibility to NASH in Japanese population. , 2007, Journal of hepatology.

[11]  G. Musso,et al.  Polymorphism in microsomal triglyceride transfer protein: A link between liver disease and atherogenic postprandial lipid profile in NASH? , 2007, Hepatology.

[12]  F. Schick,et al.  Upstream transcription factor 1 gene polymorphisms are associated with high antilipolytic insulin sensitivity and show gene–gene interactions , 2006, Journal of Molecular Medicine.

[13]  A. Rissanen,et al.  Acquired obesity increases CD68 and tumor necrosis factor-alpha and decreases adiponectin gene expression in adipose tissue: a study in monozygotic twins. , 2006, The Journal of clinical endocrinology and metabolism.

[14]  A. Häkkinen,et al.  Effects of Acquired Obesity on Endothelial Function in Monozygotic Twins , 2006, Obesity.

[15]  A. Rissanen,et al.  ACQUIRED OBESITY INCREASES CD68 AND TNF-α AND DECREASES ADIPONECTIN GENE EXPRESSION IN ADIPOSE TISSUE. A study in monozygotic twins. , 2006 .

[16]  F. Schick,et al.  Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat , 2005, Diabetologia.

[17]  Shuli Wang,et al.  Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD) , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[18]  F. Schick,et al.  Liver fat and insulin resistance are independently associated with the -514C>T polymorphism of the hepatic lipase gene. , 2005, The Journal of clinical endocrinology and metabolism.

[19]  A. Häkkinen,et al.  Acquired obesity is associated with increased liver fat, intra-abdominal fat, and insulin resistance in young adult monozygotic twins. , 2005, American journal of physiology. Endocrinology and metabolism.

[20]  A. Rissanen,et al.  Growth patterns in young adult monozygotic twin pairs discordant and concordant for obesity. , 2004, Twin research : the official journal of the International Society for Twin Studies.

[21]  A. Rissanen,et al.  Overexpression of 11beta-hydroxysteroid dehydrogenase-1 in adipose tissue is associated with acquired obesity and features of insulin resistance: studies in young adult monozygotic twins. , 2004, The Journal of clinical endocrinology and metabolism.

[22]  A. Häkkinen,et al.  Women and men have similar amounts of liver and intra-abdominal fat, despite more subcutaneous fat in women: implications for sex differences in markers of cardiovascular risk , 2004, Diabetologia.

[23]  A. Rissanen,et al.  Expression of fatty-acid-handling proteins in human adipose tissue in relation to obesity and insulin resistance , 2004, Diabetologia.

[24]  T. Saibara,et al.  Polymorphisms of microsomal triglyceride transfer protein gene and manganese superoxide dismutase gene in non-alcoholic steatohepatitis. , 2004, Journal of hepatology.

[25]  M. Saboorian,et al.  Ethnic Differences in the Prevalence of Cryptogenic Cirrhosis , 2004, American Journal of Gastroenterology.

[26]  Brian P. Mulhall,et al.  Nonalcoholic steatohepatitis , 2004, Current treatment options in gastroenterology.

[27]  J. Kaprio,et al.  Assortative mating by body height and BMI: Finnish Twins and their spouses , 2003, American Journal of Human Biology.

[28]  B. Neuschwander‐Tetri,et al.  Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference , 2003, Hepatology.

[29]  F. Brancati,et al.  The prevalence and etiology of elevated aminotransferase levels in the United States , 2003, American Journal of Gastroenterology.

[30]  C. Day,et al.  Manganese dependent superoxide dismutase (SOD2) targeting sequence polymorphism is associated with advanced fibrosis in patients with non-alcoholic fatty liver disease , 2003 .

[31]  Jaakko Kaprio,et al.  Genetic and environmental factors in health-related behaviors: studies on Finnish twins and twin families. , 2002, Twin research : the official journal of the International Society for Twin Studies.

[32]  M. Weltman,et al.  HFE mutations, hepatic iron, and fibrosis: Ethnic‐specific association of NASH with C282Y but not with fibrotic severity , 2002, Hepatology.

[33]  A. Häkkinen,et al.  Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. , 2002, The Journal of clinical endocrinology and metabolism.

[34]  J. Patrie,et al.  Is NASH underdiagnosed among African Americans? , 2002, American Journal of Gastroenterology.

[35]  L. N. Valenti,et al.  Tumor necrosis factor α promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease , 2002 .

[36]  L. N. Valenti,et al.  Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease. , 2002, Gastroenterology.

[37]  Rahul Krishnarao Patil,et al.  Ninety patients with nonalcoholic steatohepatitis: insulin resistance, familial tendency, and severity of disease , 2001, American Journal of Gastroenterology.

[38]  J. Vaupel,et al.  Evidence for a substantial genetic influence on biochemical liver function tests: results from a population-based Danish twin study. , 2001, Clinical chemistry.

[39]  M. Reitman,et al.  Lipoatrophy Revisited , 2000, Trends in Endocrinology & Metabolism.

[40]  P. Moulin,et al.  Association between microsomal triglyceride transfer protein gene polymorphism and the biological features of liver steatosis in patients with Type II diabetes , 2000, Diabetologia.

[41]  A. Häkkinen,et al.  Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients. , 2000, Diabetes.

[42]  S. Caldwell,et al.  Nonalcoholic steatohepatitis and cryptogenic cirrhosis within kindreds. , 2000, The American journal of medicine.

[43]  P. Ward,et al.  Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis. , 1998, Gastroenterology.

[44]  C. Bouchard,et al.  Genetic influences on the response of body fat and fat distribution to positive and negative energy balances in human identical twins. , 1997, The Journal of nutrition.

[45]  T. Goto,et al.  The influence of fatty liver on insulin clearance and insulin resistance in non-diabetic Japanese subjects. , 1995, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[46]  A. Thapar,et al.  Methodology for Genetic Studies of Twins and Families , 1993 .

[47]  R B Mazess,et al.  Dual-energy x-ray absorptiometry for total-body and regional bone-mineral and soft-tissue composition. , 1990, The American journal of clinical nutrition.

[48]  A. Scott,et al.  On Chi-Squared Tests for Multiway Contingency Tables with Cell Proportions Estimated from Survey Data , 1984 .

[49]  J. Sternberg,et al.  A New and Rapid Method for the Determination of Glucose by Measurement of Rate of Oxygen Consumption , 1968 .