Multiple sclerosis: a study of CXCL10 and CXCR3 co-localization in the inflamed central nervous system

[1]  H. Hartung,et al.  Chemokines and chemokine receptors in inflammatory demyelinating neuropathies: a central role for IP-10. , 2002, Brain : a journal of neurology.

[2]  R. Ransohoff,et al.  Investigating chemokines and chemokine receptors in patients with multiple sclerosis: opportunities and challenges. , 2001, Archives of neurology.

[3]  C. V. Jensen,et al.  Chemokines CXCL10 and CCL2: differential involvement in intrathecal inflammation in multiple sclerosis , 2001, European journal of neurology.

[4]  R. Ransohoff,et al.  CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis. , 2001, The American journal of pathology.

[5]  H. Keirstead,et al.  Neutralization of the Chemokine CXCL10 Reduces Inflammatory Cell Invasion and Demyelination and Improves Neurological Function in a Viral Model of Multiple Sclerosis1 , 2001, The Journal of Immunology.

[6]  J. Flier,et al.  Differential expression of CXCR3 targeting chemokines CXCL10, CXCL9, and CXCL11 in different types of skin inflammation , 2001, The Journal of pathology.

[7]  A. Compston,et al.  Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis , 2001, Annals of neurology.

[8]  S. Kunkel,et al.  EncephalomyelitisDuring Experimental Autoimmune Accumulation in the Central Nervous System T Cell + Control of Encephalitogenic CD4 -Inducible Protein-10) g CXCL10 (IFN-and , 2001 .

[9]  H. Lassmann,et al.  Migratory activity and functional changes of green fluorescent effector cells before and during experimental autoimmune encephalomyelitis. , 2001, Immunity.

[10]  R. Bergamaschi,et al.  Serum and CSF levels of MCP-1 and IP-10 in multiple sclerosis patients with acute and stable disease and undergoing immunomodulatory therapies , 2001, Journal of Neuroimmunology.

[11]  Y. Itoyama,et al.  Chemokine receptor expression on T cells in blood and cerebrospinal fluid at relapse and remission of multiple sclerosis: imbalance of Th1/Th2-associated chemokine signaling , 2001, Journal of Neuroimmunology.

[12]  T. Hamilton,et al.  Expression of Mig (Monokine Induced by Interferon-γ) Is Important in T Lymphocyte Recruitment and Host Defense Following Viral Infection of the Central Nervous System1 , 2001, Journal of Immunology.

[13]  M. Serio,et al.  Cell cycle-dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity. , 2001, The Journal of clinical investigation.

[14]  C. D. DE GROOT,et al.  The role of chemokines and chemokine receptors in CNS inflammation. , 2001 .

[15]  L. Trentin,et al.  CXC chemokines IP-10 and mig expression and direct migration of pulmonary CD8+/CXCR3+ T cells in the lungs of patients with HIV infection and T-cell alveolitis. , 2000, American journal of respiratory and critical care medicine.

[16]  S. Majumder,et al.  Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation , 2000, Immunological reviews.

[17]  J. Parisi,et al.  Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination , 2000, Annals of neurology.

[18]  R. Ransohoff,et al.  Chemokine receptor antagonism as a new therapy for multiple sclerosis , 2000, Expert opinion on investigational drugs.

[19]  J. Newcombe,et al.  Expression of the interferon‐γ‐inducible chemokines IP‐10 and Mig and their receptor, CXCR3, in multiple sclerosis lesions , 2000, Neuropathology and applied neurobiology.

[20]  K. Matsushima,et al.  International union of pharmacology. XXII. Nomenclature for chemokine receptors. , 2000, Pharmacological reviews.

[21]  A. Zlotnik,et al.  Chemokines: a new classification system and their role in immunity. , 2000, Immunity.

[22]  J. Noseworthy Progress in determining the causes and treatment of multiple sclerosis , 1999, Nature.

[23]  H. Weiner,et al.  CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[24]  R. Rabin,et al.  Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling. , 1999, Journal of immunology.

[25]  Jakob S. Jensen,et al.  Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. , 1999, The Journal of clinical investigation.

[26]  M. Chilosi,et al.  Involvement of the IP-10 chemokine in sarcoid granulomatous reactions. , 1998, Journal of immunology.

[27]  James G. Boyd,et al.  Interferon–inducible T Cell Alpha Chemoattractant (I-TAC): A Novel Non-ELR CXC Chemokine with Potent Activity on Activated T Cells through Selective High Affinity Binding to CXCR3 , 1998, The Journal of experimental medicine.

[28]  C. Mackay,et al.  The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. , 1998, The Journal of clinical investigation.

[29]  A. Luster,et al.  Chemokines--chemotactic cytokines that mediate inflammation. , 1998, The New England journal of medicine.

[30]  T. Sørensen,et al.  Etiology and pathogenesis of multiple sclerosis. , 1998, Seminars in neurology.

[31]  R. Ransohoff,et al.  Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis. , 1997, The American journal of pathology.

[32]  Simon A. Jones,et al.  Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes , 1996, The Journal of experimental medicine.

[33]  M. Christiansen,et al.  Qualitative assessment of intrathecal IgG synthesis by isoelectric focusing and immunodetection: interlaboratory reproducibility and interobserver agreement. , 1996, Scandinavian journal of clinical and laboratory investigation.

[34]  R. Ransohoff,et al.  In situ hybridization analysis of glial fibrillary acidic protein mRNA reveals evidence of biphasic astrocyte activation during acute experimental autoimmune encephalomyelitis. , 1996, The American journal of pathology.

[35]  Hans Lassmann,et al.  Monocyte/macrophage differentiation in early multiple sclerosis lesions , 1995, Annals of neurology.

[36]  P. Gray,et al.  Chemokine expression in murine experimental allergic encephalomyelitis , 1995, Journal of Neuroimmunology.

[37]  W. Brück,et al.  Oligodendrocytes in the early course of multiple sclerosis , 1994, Annals of neurology.

[38]  R. Ransohoff,et al.  Astrocyte expression of mRNA encoding cytokines IP‐10 and JE/MCP‐1 in experimental autoimmune encephalomyelitis , 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[39]  F. Da Demyelinating optic neuritis: clinical features and differential diagnosis. , 1991 .

[40]  W. Hickey,et al.  T‐lymphocyte entry into the central nervous system , 1991, Journal of neuroscience research.

[41]  B. Engelhardt,et al.  Interaction of T Lymphocytes with Cerebral Endothelial Cells in vitro , 1991, Brain pathology.

[42]  A. A. Eisen,et al.  MRI in the diagnosis of MS , 1988, Neurology.