Smad3 activates the Sox9-dependent transcription on chromatin.

[1]  L. Qin,et al.  Gelatin microspheres containing TGF-beta3 enhance the chondrogenesis of mesenchymal stem cells in modified pellet culture. , 2008, Biomacromolecules.

[2]  G. Finkenzeller,et al.  Differential expression pattern of extracellular matrix molecules during chondrogenesis of mesenchymal stem cells from bone marrow and adipose tissue. , 2006, Tissue engineering.

[3]  G. Finkenzeller,et al.  Mesenchymal stem cells maintain TGF-beta-mediated chondrogenic phenotype in alginate bead culture. , 2006, Tissue engineering.

[4]  N. Taniguchi,et al.  Sox9 and p300 Cooperatively Regulate Chromatin-mediated Transcription* , 2005, Journal of Biological Chemistry.

[5]  D. Edelman,et al.  The homeobox transcription factor Barx2 regulates chondrogenesis during limb development , 2005, Development.

[6]  Takayuki Furumatsu,et al.  Smad3 Induces Chondrogenesis through the Activation of SOX9 via CREB-binding Protein/p300 Recruitment*[boxs] , 2005, Journal of Biological Chemistry.

[7]  J. I. Izpisúa Belmonte,et al.  Transcriptional coactivator PGC-1alpha regulates chondrogenesis via association with Sox9. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[8]  Boon Chin Heng,et al.  Directing Stem Cell Differentiation into the Chondrogenic Lineage In Vitro , 2004, Stem cells.

[9]  Kozo Nakamura,et al.  The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage. , 2004, Arthritis and rheumatism.

[10]  S. Tapscott,et al.  In vitro transcription system delineates the distinct roles of the coactivators pCAF and p300 during MyoD/E47-dependent transactivation. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[11]  A. Zorn,et al.  Smad2 and Smad3 coordinately regulate craniofacial and endodermal development. , 2004, Developmental biology.

[12]  P. McCrea,et al.  Interactions between Sox9 and β-catenin control chondrocyte differentiation , 2004 .

[13]  T. Underhill,et al.  MAP kinases in chondrocyte differentiation. , 2003, Developmental biology.

[14]  H. Asahara,et al.  Transcriptional Co-activators CREB-binding Protein and p300 Regulate Chondrocyte-specific Gene Expression via Association with Sox9* , 2003, Journal of Biological Chemistry.

[15]  Hiromichi Nagasawa,et al.  RETRACTED: The Chromatin-Remodeling Complex WINAC Targets a Nuclear Receptor to Promoters and Is Impaired in Williams Syndrome , 2003, Cell.

[16]  J. Massagué,et al.  Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus , 2003, Cell.

[17]  A. Bird,et al.  Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals , 2003, Nature Genetics.

[18]  M. Groudine,et al.  Controlling the double helix , 2003, Nature.

[19]  Marie-Christine Chaboissier,et al.  The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. , 2002, Genes & development.

[20]  E. Li.  Chromatin modification and epigenetic reprogramming in mammalian development , 2002, Nature Reviews Genetics.

[21]  R. Roeder,et al.  SOX9 interacts with a component of the human thyroid hormone receptor-associated protein complex. , 2002, Nucleic acids research.

[22]  T. Hunter,et al.  Dual Roles of p300 in Chromatin Assembly and Transcriptional Activation in Cooperation with Nucleosome Assembly Protein 1 In Vitro , 2002, Molecular and Cellular Biology.

[23]  S. Mundlos,et al.  Role of Runx genes in chondrocyte differentiation. , 2002, Developmental biology.

[24]  M. Montminy,et al.  Chromatin-Dependent Cooperativity between Constitutive and Inducible Activation Domains in CREB , 2001, Molecular and Cellular Biology.

[25]  V. Lefebvre,et al.  L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway. , 2001, Osteoarthritis and cartilage.

[26]  M. Muramatsu,et al.  Multistep Chromatin Assembly on Supercoiled Plasmid DNA by Nucleosome Assembly Protein-1 and ATP-utilizing Chromatin Assembly and Remodeling Factor* , 2001, The Journal of Biological Chemistry.

[27]  N. L. La Thangue,et al.  p300/CBP proteins: HATs for transcriptional bridges and scaffolds. , 2001, Journal of cell science.

[28]  J. Espinosa,et al.  Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment. , 2001, Molecular cell.

[29]  E. Schwarz,et al.  Smad2 and 3 Mediate Transforming Growth Factor-β1-Induced Inhibition of Chondrocyte Maturation* *The work was supported by National Health Services Grant AR-38945 (to R.J.O.) and an Orthopaedic Research Education Foundation Award (to C.M.F.). , 2000, Endocrinology.

[30]  M. Muramatsu,et al.  p300-mediated acetylation facilitates the transfer of histone H2A-H2B dimers from nucleosomes to a histone chaperone. , 2000, Genes & development.

[31]  S. Murakami,et al.  Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[32]  K. Nakamura,et al.  p38 mitogen-activated protein kinase functionally contributes to chondrogenesis induced by growth/differentiation factor-5 in ATDC5 cells. , 1999, Experimental cell research.

[33]  R. Kobayashi,et al.  ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly. , 1999, Genes & development.

[34]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[35]  X. F. Wang,et al.  Targeted Disruption of Smad3 Reveals an Essential Role in Transforming Growth Factor β-Mediated Signal Transduction , 1999, Molecular and Cellular Biology.

[36]  P. Grant,et al.  Transcriptional activators direct histone acetyltransferase complexes to nucleosomes , 1998, Nature.

[37]  C. Glass,et al.  Transcription factor-specific requirements for coactivators and their acetyltransferase functions. , 1998, Science.

[38]  Kohei Miyazono,et al.  TGF-β signalling from cell membrane to nucleus through SMAD proteins , 1997, Nature.

[39]  Patrick P.L. Tam,et al.  SOX9 directly regulates the type-ll collagen gene , 1997, Nature Genetics.

[40]  Donald M. Bell,et al.  SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. , 1997, Developmental biology.

[41]  R. Kobayashi,et al.  Drosophila NAP-1 is a core histone chaperone that functions in ATP-facilitated assembly of regularly spaced nucleosomal arrays , 1996, Molecular and cellular biology.

[42]  M. Sporn,et al.  TGF-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases. , 1993, Developmental biology.

[43]  W. Hozack,et al.  Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt signaling cross-talk. , 2003, The Journal of biological chemistry.