Zirconium-catalyzed and zirconium-promoted cyclization reactions of non-conjugated dienes with alkylmagnesium halides to give cycloalkylmethylmagnesium derivatives☆

[1]  E. Negishi,et al.  Multiple Mechanistic Pathways for Zirconium-Catalyzed Carboalumination of Alkynes. Requirements for Cyclic Carbometalation Processes Involving C−H Activation , 1996 .

[2]  J. Ziller,et al.  Mechanism and Stereochemistry of the Zirconocene-Catalyzed Cyclomagnesiation of Dienes , 1994 .

[3]  E. Negishi,et al.  Zirconium catalyzed CC bond formation reaction of conjugated diynes with EtMgBr , 1993 .

[4]  E. Negishi,et al.  Conversion of non-conjugated dienes into conjugated diene-zirconocenes via multipositional regioisomerization , 1993 .

[5]  R. Waymouth,et al.  Stereoselective cyclomagnesiation of 1,6-heptadienes catalyzed by zirconocenes: Effects of substituents, solvent and magnesium reagents , 1992 .

[6]  A. Hoveyda,et al.  The mechanism of the zirconium-catalyzed carbomagnesiation reaction. Efficient and selective catalytic carbomagnesiation with higher alkyls of magnesium , 1992 .

[7]  E. Negishi,et al.  Novel head-to-tail alkyl-alkene or alkene-alkene coupling via zirconium-catalyzed reaction of alkylmagnesium derivatives with monosubstituted alkenes , 1992 .

[8]  P. Muller,et al.  A zirconium catalysed synthesis of 1,4-dimagnesium reagents. , 1991 .

[9]  E. Negishi,et al.  Remarkably pair- and regioselective carbon-carbon bond-forming reaction of zirconacyclopentane derivatives with Grignard reagents , 1991 .

[10]  R. Waymouth,et al.  Zirconium-catalyzed diene and alkyl-alkene coupling reactions with magnesium reagents , 1991 .

[11]  A. Hoveyda,et al.  Stereoselective formation of carbon-carbon bonds through metal catalysis. The zirconium-catalyzed ethylmagnesiation reaction , 1991 .

[12]  E. Negishi,et al.  A general and convenient procedure for the preparation of zirconocene complexes of alkenes and conjugated dienes , 1991 .

[13]  N. Thinh,et al.  A convenient procedure for hydrozirconation of alkynes with iso-BuZrCp2Cl generated in situ by treatment of Cp2ZrCl2 with tert-butylmagnesium chloride , 1991 .

[14]  W. A. Nugent,et al.  Zirconium-mediated ring construction from dienes: remarkable effect of ligands on stereochemistry , 1989 .

[15]  E. Negishi,et al.  Metal-promoted cyclization. 28. Regioselective and diastereoselective alkyl-alkene and alkene-alkene coupling promoted by zirconocene and hafnocene , 1989 .

[16]  C. Krüger,et al.  (1‐Alken)(trimethylphosphan)zirconocen‐Komplexe: Darstellung, Charakterisierung und Reaktivität , 1989 .

[17]  J. Tour,et al.  Metal-promoted cyclization. 19. Novel bicyclization of enynes and diynes promoted by zirconocene derivatives and conversion of zirconabicycles into bicyclic enones via carbonylation , 1989 .

[18]  F. Lamaty,et al.  Zirconocene-promoted stereoselective bicyclization of 1,6- and 1,7-dienes to produce trans-zirconabicyclo[3.3.0]octanes and cis-zirconabicyclo[4.3.0]nonanes , 1989 .

[19]  S. Buchwald,et al.  Group 4 Metal Complexes of Benzynes, Cycloalkynes, Acyclic Alkynes, and Alkenes , 1988 .

[20]  W. A. Nugent,et al.  Stereoselective cyclization of enynes mediated by metallocene reagents , 1988 .

[21]  W. A. Nugent,et al.  Cyclization of diacetylenes to E,E exocyclic dienes. Complementary procedures based on titanium and zirconium reagents , 1987 .

[22]  E. Negishi,et al.  Zirconium-promoted bicyclization of enynes. Effects of enyne structure , 1987 .

[23]  U. Dzhemilev,et al.  Homogeneous zirconium based catalysts in organic synthesis , 1986 .

[24]  E. Negishi,et al.  Reaction of zirconocene dichloride with alkyllithiums or alkyl grignard reagents as a convenient method for generating a “zirconocene” equivalant and its use in zirconium-promoted cyclization of alkenes, alkynes, dienes, enynes, and diynes☆ , 1986 .

[25]  E. Negishi,et al.  Controlled carbometalation. 20. Carbometalation reaction of alkynes with organoalene-zirconocene derivatives as a route to stereo-and regiodefined trisubstituted alkenes , 1985 .

[26]  J. Tour,et al.  Metal promoted cyclization. 7. Zirconium-promoted bicyclization of enynes , 1985 .

[27]  W. Bailey,et al.  Reactions of tert-butyllithium with .alpha.,.omega.-dihaloalkanes. Evidence for single-electron-transfer-mediated metal-halogen interchange involving alkyl radical-halide ion adducts , 1984 .

[28]  E. Negishi,et al.  Reaction of alkenes and dienes with t-butylmagnesium halides and zirconocene dihalides. A convenient procedure for hydrozirconation and a novel t-butylzirconation of conjugated alkenes , 1984 .

[29]  M. Tiecco,et al.  Selective mono-arylation and -alkylation of bis(alkylthio)benzenes , 1983 .

[30]  Tadao Yoshida,et al.  Mechanism of the zirconium-catalyzed carboalumination of alkynes. Evidence for direct carboalumination , 1981 .

[31]  E. Negishi Bimetallic catalytic systems containing Ti, Zr, Ni, and Pd. Their applications to selective organic syntheses , 1981 .

[32]  E. Negishi,et al.  Palladium-catalyzed cross-coupling reaction of homoallylic or homopropargylic organozincs with alkenyl halides as a new selective route to 1,5-dienes and 1,5-enynes , 1980 .

[33]  E. Negishi,et al.  Selective carbon-carbon bond formation via transition metal catalysts. 8. Controlled carbometalation. Reaction of acetylenes with organoalane-zirconocene dichloride complexes as a route to stereo- and regio-defined trisubstituted olefins , 1978 .

[34]  A. Hosomi,et al.  Chemistry of organosilicon compounds. 99. Conjugate addition of allylsilanes to .alpha.,.beta.-enones. A New method of stereoselective introduction of the angular allyl group in fused cyclic .alpha.,.beta.-enones , 1977 .

[35]  C. Sih,et al.  Total synthesis of prostaglandins. VI. Stereospecific total synthesis of prostaglandins via reaction of .alpha.-alkylcyclopentenones with organocuprates , 1975 .

[36]  E. C. Ashby,et al.  Composition of Grignard compounds. VI. Nature of association in tetrahydrofuran and diethyl ether solutions , 1969 .

[37]  M. Rathke,et al.  A fast reaction of organoboranes with iodine under the influence of base. A convenient procedure for the conversion of terminal olefins into primary iodides via hydroboration-iodination , 1968 .

[38]  D. Grant,et al.  Carbon-13 magnetic resonance. IX. Methylcyclohexanes , 1967 .

[39]  J. Eastham,et al.  Colored indicators for simple direct titration of magnesium and lithium reagents , 1967 .

[40]  E. C. Ashby,et al.  Concerning the Structure of the Grignard Reagent. II.1 In Diethyl Ether. Relevance of Grignard Composition to the Mechanism of Addition to Ketones , 1964 .