Critical Review of Health Impacts of Wildfire Smoke Exposure

Background: Wildfire activity is predicted to increase in many parts of the world due to changes in temperature and precipitation patterns from global climate change. Wildfire smoke contains numerous hazardous air pollutants and many studies have documented population health effects from this exposure. Objectives: We aimed to assess the evidence of health effects from exposure to wildfire smoke and to identify susceptible populations. Methods: We reviewed the scientific literature for studies of wildfire smoke exposure on mortality and on respiratory, cardiovascular, mental, and perinatal health. Within those reviewed papers deemed to have minimal risk of bias, we assessed the coherence and consistency of findings. Discussion: Consistent evidence documents associations between wildfire smoke exposure and general respiratory health effects, specifically exacerbations of asthma and chronic obstructive pulmonary disease. Growing evidence suggests associations with increased risk of respiratory infections and all-cause mortality. Evidence for cardiovascular effects is mixed, but a few recent studies have reported associations for specific cardiovascular end points. Insufficient research exists to identify specific population subgroups that are more susceptible to wildfire smoke exposure. Conclusions: Consistent evidence from a large number of studies indicates that wildfire smoke exposure is associated with respiratory morbidity with growing evidence supporting an association with all-cause mortality. More research is needed to clarify which causes of mortality may be associated with wildfire smoke, whether cardiovascular outcomes are associated with wildfire smoke, and if certain populations are more susceptible. Citation: Reid CE, Brauer M, Johnston FH, Jerrett M, Balmes JR, Elliott CT. 2016. Critical review of health impacts of wildfire smoke exposure. Environ Health Perspect 124:1334–1343; http://dx.doi.org/10.1289/ehp.1409277

[1]  S. Henderson,et al.  Evaluation of a spatially resolved forest fire smoke model for population-based epidemiologic exposure assessment , 2014, Journal of Exposure Science and Environmental Epidemiology.

[2]  A. Tonkin,et al.  Impact of Fine Particulate Matter (PM2.5) Exposure During Wildfires on Cardiovascular Health Outcomes , 2015, Journal of the American Heart Association.

[3]  Kevin Y. Tse,et al.  Effect of catastrophic wildfires on asthmatic outcomes in obese children: breathing fire. , 2015, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[4]  A. Tonkin,et al.  Forest Fire Smoke Exposures and Out-of-Hospital Cardiac Arrests in Melbourne, Australia: A Case-Crossover Study , 2015, Environmental health perspectives.

[5]  Health outcomes associated with smoke exposure in Albuquerque, New Mexico, during the 2011 Wallow fire. , 2015, Journal of public health management and practice : JPHMP.

[6]  J. Sunyer,et al.  Short-term effects of particulate matter on mortality during forest fires in Southern Europe: results of the MED-PARTICLES Project , 2015, Occupational and Environmental Medicine.

[7]  M. Bell,et al.  A systematic review of the physical health impacts from non-occupational exposure to wildfire smoke. , 2015, Environmental research.

[8]  A. Tobías,et al.  Influence of advections of particulate matter from biomass combustion on specific-cause mortality in Madrid in the period 2004–2009 , 2015, Environmental Science and Pollution Research.

[9]  S. Henderson,et al.  Air pollution events from forest fires and emergency department attendances in Sydney, Australia 1996–2007: a case-crossover analysis , 2014, Environmental Health.

[10]  I. Annesi-Maesano,et al.  Non-Accidental Health Impacts of Wildfire Smoke , 2014, International journal of environmental research and public health.

[11]  I. Mattos,et al.  Low birth weight at term and the presence of fine particulate matter and carbon monoxide in the Brazilian Amazon: a population-based retrospective cohort study , 2014, BMC Pregnancy and Childbirth.

[12]  P. Saldiva,et al.  Acute Effects of Particulate Matter and Black Carbon from Seasonal Fires on Peak Expiratory Flow of Schoolchildren in the Brazilian Amazon , 2014, PloS one.

[13]  Tracey J. Woodruff,et al.  The Navigation Guide Systematic Review Methodology: A Rigorous and Transparent Method for Translating Environmental Health Science into Better Health Outcomes , 2014, Environmental health perspectives.

[14]  Michael Brauer,et al.  Impact of Noise and Air Pollution on Pregnancy Outcomes , 2014, Epidemiology.

[15]  Melvyn W B Zhang,et al.  Impact of 2013 south Asian haze crisis: study of physical and psychological symptoms and perceived dangerousness of pollution level , 2014, BMC Psychiatry.

[16]  M. Bottai,et al.  Mortality Related to Air Pollution with the Moscow Heat Wave and Wildfire of 2010 , 2014, Epidemiology.

[17]  Scott J. Goetz,et al.  Terrestrial and Inland Water Systems , 2014 .

[18]  T. Loboda,et al.  Modeling acute respiratory illness during the 2007 San Diego wildland fires using a coupled emissions-transport system and generalized additive modeling , 2013, Environmental Health.

[19]  A. Carvalho,et al.  Emissions generated by sugarcane burning promote genotoxicity in rural workers: a case study in Barretos, Brazil , 2013, Environmental Health.

[20]  S. Henderson,et al.  Air pollution from bushfires and their association with hospital admissions in Sydney, Newcastle and Wollongong, Australia 1994–2007 , 2013, Australian and New Zealand journal of public health.

[21]  M. Flannigan,et al.  Global wildland fire season severity in the 21st century , 2013 .

[22]  E. Ignotti,et al.  Circulatory disease mortality rates in the elderly and exposure to PM(2.5) generated by biomass burning in the Brazilian Amazon in 2005. , 2013, Cadernos de saude publica.

[23]  Rajesh Kumar,et al.  Household air pollution and stillbirths in India: analysis of the DLHS-II National Survey. , 2013, Environmental research.

[24]  Sarah B Henderson,et al.  Time series analysis of fine particulate matter and asthma reliever dispensations in populations affected by forest fires , 2013, Environmental Health.

[25]  J. Last,et al.  Cell-specific oxidative stress and cytotoxicity after wildfire coarse particulate matter instillation into mouse lung. , 2013, Toxicology and applied pharmacology.

[26]  L. Miller Persistent immune effects of wildfire PM exposure during childhood development , 2013 .

[27]  M. Hande,et al.  Physicochemical and toxicological characteristics of urban aerosols during a recent Indonesian biomass burning episode , 2013, Environmental Science and Pollution Research.

[28]  A. Moffat,et al.  Health Impacts of Wildfires , 2012, PLoS currents.

[29]  Ana G Rappold,et al.  Cardio-respiratory outcomes associated with exposure to wildfire smoke are modified by measures of community health , 2012, Environmental Health.

[30]  A. P. D. Ponce de Leon,et al.  Association between fine particulate matter and the peak expiratory flow of schoolchildren in the Brazilian subequatorial Amazon: a panel study. , 2012, Environmental research.

[31]  S. Henderson,et al.  Measures of forest fire smoke exposure and their associations with respiratory health outcomes , 2012, Current opinion in allergy and clinical immunology.

[32]  D. Holstius,et al.  Birth Weight following Pregnancy during the 2003 Southern California Wildfires , 2012, Environmental health perspectives.

[33]  J. Dórea,et al.  Amazon Forest Fires Between 2001 and 2006 and Birth Weight in Porto Velho , 2012, Bulletin of Environmental Contamination and Toxicology.

[34]  P. Artaxo,et al.  Micronucleus frequency in children exposed to biomass burning in the Brazilian Legal Amazon region: a control case study , 2012, BMC oral health.

[35]  Michael Brauer,et al.  Estimated Global Mortality Attributable to Smoke from Landscape Fires , 2012, Environmental health perspectives.

[36]  Firas H. Kobeissy,et al.  Psychiatric Disorders , 2012, Methods in Molecular Biology.

[37]  J. Last,et al.  Why is particulate matter produced by wildfires toxic to lung macrophages? , 2011, Toxicology and applied pharmacology.

[38]  H. Aung,et al.  Fine particulate matter from urban ambient and wildfire sources from California's San Joaquin Valley initiate differential inflammatory, oxidative stress, and xenobiotic responses in human bronchial epithelial cells. , 2011, Toxicology in vitro : an international journal published in association with BIBRA.

[39]  M. Carraway,et al.  Peat Bog Wildfire Smoke Exposure in Rural North Carolina Is Associated with Cardiopulmonary Emergency Department Visits Assessed through Syndromic Surveillance , 2011, Environmental health perspectives.

[40]  H. Suh,et al.  Markers of Inflammation in Alveolar Cells Exposed to Fine Particulate Matter From Prescribed Fires and Urban Air , 2011, Journal of occupational and environmental medicine.

[41]  K. Katsouyanni,et al.  Forest fires are associated with elevated mortality in a dense urban setting , 2011, Occupational and Environmental Medicine.

[42]  S. Henderson,et al.  Extreme air pollution events from bushfires and dust storms and their association with mortality in Sydney, Australia 1994-2007. , 2011, Environmental research.

[43]  M. Brauer,et al.  Three Measures of Forest Fire Smoke Exposure and Their Associations with Respiratory and Cardiovascular Health Outcomes in a Population-Based Cohort , 2011, Environmental health perspectives.

[44]  P. Wiwatanadate,et al.  Acute effects of air pollution on peak expiratory flow rates and symptoms among asthmatic patients in Chiang Mai, Thailand. , 2011, International journal of hygiene and environmental health.

[45]  A. Figueiras,et al.  Respiratory and mental health effects of wildfires: an ecological study in Galician municipalities (north-west Spain) , 2011, Environmental health : a global access science source.

[46]  F. Gonçalves,et al.  Long-range ozone transport and its impact on respiratory and cardiovascular health in the north of Portugal , 2011, International journal of biometeorology.

[47]  M. Abramson,et al.  The effects of bushfire smoke on respiratory health , 2011, Respirology.

[48]  J. Ramsdell,et al.  2007 San Diego Wildfires and Asthmatics , 2011, The Journal of asthma : official journal of the Association for the Care of Asthma.

[49]  M. Brauer,et al.  Residential Air Pollution and Otitis Media During the First Two Years of Life , 2011, Epidemiology.

[50]  Narayan Sastry,et al.  Forest fires, air pollution, and mortality in Southeast Asia , 2002, Demography.

[51]  R. Mellon,et al.  Psychological distress following wildfires disaster in a rural part of Greece: a case-control population-based study. , 2011, International journal of emergency mental health.

[52]  Thomas M Seed,et al.  Acute Effects , 2011 .

[53]  J. Schauer,et al.  Associations of Primary and Secondary Organic Aerosols With Airway and Systemic Inflammation in an Elderly Panel Cohort , 2010, Epidemiology.

[54]  A. Peters,et al.  Particulate Matter Air Pollution and Cardiovascular Disease: An Update to the Scientific Statement From the American Heart Association , 2010, Circulation.

[55]  F. Mitloehner,et al.  Lung antioxidant and cytokine responses to coarse and fine particulate matter from the great California wildfires of 2008 , 2010, Inhalation toxicology.

[56]  P. Saldiva,et al.  Impact of outdoor biomass air pollution on hypertension hospital admissions , 2010, Journal of Epidemiology & Community Health.

[57]  T. Lumley,et al.  Effects of Bushfire Smoke on Daily Mortality and Hospital Admissions in Sydney, Australia , 2010, Epidemiology.

[58]  R. Slama,et al.  International Collaboration on Air Pollution and Pregnancy Outcomes (ICAPPO) , 2009, International journal of environmental research and public health.

[59]  Sandra de Souza Hacon,et al.  Impact on human health of particulate matter emitted from burnings in the Brazilian Amazon region. , 2010, Revista de saude publica.

[60]  H. Coates,et al.  Natural history, definitions, risk factors and burden of otitis media , 2009, The Medical journal of Australia.

[61]  M. Krawchuk,et al.  Implications of changing climate for global wildland fire , 2009 .

[62]  Tze-san Lee,et al.  Risk factors associated with clinic visits during the 1999 forest fires near the Hoopa Valley Indian Reservation, California, USA , 2009, International journal of environmental health research.

[63]  K. Pinkerton,et al.  California Wildfires of 2008: Coarse and Fine Particulate Matter Toxicity , 2009, Environmental health perspectives.

[64]  M. Abramson,et al.  The impact of smoke on respiratory hospital outcomes during the 2002–2003 bushfire season, Victoria, Australia , 2009, Respirology.

[65]  B. Ostro,et al.  The relationship of respiratory and cardiovascular hospital admissions to the southern California wildfires of 2003 , 2008, Occupational and Environmental Medicine.

[66]  W. Zin,et al.  Comparative respiratory toxicity of particles produced by traffic and sugar cane burning. , 2008, Environmental research.

[67]  F. Johnston,et al.  Vegetation fire smoke, indigenous status and cardio-respiratory hospital admissions in Darwin, Australia, 1996–2005: a time-series study , 2008, Environmental health : a global access science source.

[68]  S. Jayachandran Air Quality and Early-Life Mortality: Evidence from Indonesia's Wildfires , 2008 .

[69]  F. Johnston,et al.  Ambient biomass smoke and cardio-respiratory hospital admissions in Darwin, Australia , 2007, BMC public health.

[70]  Chris Piacitelli,et al.  Particle size-dependent radical generation from wildland fire smoke. , 2007, Toxicology.

[71]  P. Saldiva,et al.  Air pollution from biomass burning and asthma hospital admissions in a sugar cane plantation area in Brazil , 2007, Journal of Epidemiology and Community Health.

[72]  Terry L. Schell,et al.  Psychiatric disorders among adults seeking emergency disaster assistance after a wildland-urban interface fire. , 2007, Psychiatric services.

[73]  M. Brauer,et al.  Woodsmoke Health Effects: A Review , 2007, Inhalation toxicology.

[74]  Fay H Johnston,et al.  Vegetation fires, particulate air pollution and asthma: A panel study in the Australian monsoon tropics , 2006, International journal of environmental health research.

[75]  S. Vedal,et al.  Wildfire air pollution and daily mortality in a large urban area. , 2006, Environmental research.

[76]  T. Swetnam,et al.  Warming and Earlier Spring Increase Western U.S. Forest Wildfire Activity , 2006, Science.

[77]  J. Wedzicha,et al.  Acute exacerbations , 2006, BMJ : British Medical Journal.

[78]  Shilu Tong,et al.  Air particulate pollution due to bushfires and respiratory hospital admissions in Brisbane, Australia , 2006, International journal of environmental health research.

[79]  M. Brauer,et al.  Population health effects of air quality changes due to forest fires in British Columbia in 2003: estimates from physician-visit billing data. , 2006, Canadian journal of public health = Revue canadienne de sante publique.

[80]  Antonella Zanobetti,et al.  The Impact of Sugar Cane–Burning Emissions on the Respiratory System of Children and the Elderly , 2006, Environmental health perspectives.

[81]  D. Mannino,et al.  Cardiorespiratory hospitalizations associated with smoke exposure during the 1997, Southeast Asian forest fires. , 2005, International journal of hygiene and environmental health.

[82]  Peter Gibbon,et al.  Posttraumatic Stress Disorder and General Psychopathology in Children and Adolescents following a Wildfire Disaster , 2005, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[83]  A. Weaver,et al.  Detecting the effect of climate change on Canadian forest fires , 2004 .

[84]  F. Johnston,et al.  Exposure to bushfire smoke and asthma: an ecological study , 2002, The Medical journal of Australia.

[85]  D. Mannino,et al.  Wildland forest fire smoke: health effects and intervention evaluation, Hoopa, California, 1999. , 2002, The Western journal of medicine.

[86]  J. Zelikoff,et al.  THE TOXICOLOGY OF INHALED WOODSMOKE , 2002, Journal of toxicology and environmental health. Part B, Critical reviews.

[87]  J. Hogg,et al.  Cytokines involved in the systemic inflammatory response induced by exposure to particulate matter air pollutants (PM(10)). , 2001, American journal of respiratory and critical care medicine.

[88]  G. Böhm,et al.  Assessment of the Effects of Sugar Cane Plantation Burning on Daily Counts of Inhalation Therapy , 2000, Journal of the Air & Waste Management Association.

[89]  S. Leeder,et al.  Acute effects of bushfires on peak expiratory flow rates in children with wheeze: a time series analysis , 2000, Australian and New Zealand journal of public health.

[90]  J. Hogg,et al.  The human bone marrow response to acute air pollution caused by forest fires. , 2000, American journal of respiratory and critical care medicine.

[91]  S. Leeder,et al.  Asthma presentations to emergency departments in western Sydney during the January 1994 Bushfires. , 1996, International journal of epidemiology.

[92]  B. Fasher,et al.  Acute exacerbations of asthma and bushfires , 1994, The Lancet.

[93]  M Lipsett,et al.  The 1987 forest fire disaster in California: assessment of emergency room visits. , 1990, Archives of environmental health.

[94]  L. Friberg Air Pollution , 1984, Svenska lakartidningen.