Construction of a computable cell proliferation network focused on non-diseased lung cells

[1]  Christopher M Waters,et al.  Epithelial repair mechanisms in the lung. , 2010, American journal of physiology. Lung cellular and molecular physiology.

[2]  Susumu Goto,et al.  KEGG for representation and analysis of molecular networks involving diseases and drugs , 2009, Nucleic Acids Res..

[3]  Sean F. Eddy,et al.  The Role of Hypoxia in 2-Butoxyethanol–Induced Hemangiosarcoma , 2009, Toxicological sciences : an official journal of the Society of Toxicology.

[4]  Emanuel F Petricoin,et al.  Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693 , 2010, BMC Genomics.

[5]  Shih-Yin Tsai,et al.  Emerging roles of E2Fs in cancer: an exit from cell cycle control , 2009, Nature Reviews Cancer.

[6]  P. Tsao,et al.  Notch signaling controls the balance of ciliated and secretory cell fates in developing airways , 2009, Development.

[7]  Anindya Dutta,et al.  p21 in cancer: intricate networks and multiple activities , 2009, Nature Reviews Cancer.

[8]  Z. Mosenifar,et al.  Differentiating COPD from Asthma in Clinical Practice , 2009, Postgraduate medicine.

[9]  Jörg Rahnenführer,et al.  Robert Gentleman, Vincent Carey, Wolfgang Huber, Rafael Irizarry, Sandrine Dudoit (2005): Bioinformatics and Computational Biology Solutions Using R and Bioconductor , 2009 .

[10]  Thomas Mammone,et al.  SIRT1 promotes differentiation of normal human keratinocytes. , 2009, The Journal of investigative dermatology.

[11]  I. Adcock,et al.  Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction , 2008, European Respiratory Journal.

[12]  J. Zavadil,et al.  eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy , 2008, The Journal of cell biology.

[13]  R. Medzhitov,et al.  Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance , 2008, Proceedings of the National Academy of Sciences.

[14]  M. Kool,et al.  Dendritic cells in asthma and COPD: opportunities for drug development. , 2007, Current opinion in immunology.

[15]  S. Hooper,et al.  Identification of glucocorticoid‐regulated genes that control cell proliferation during murine respiratory development , 2007, The Journal of physiology.

[16]  M. Blasco,et al.  Cellular Senescence in Cancer and Aging , 2007, Cell.

[17]  X. Bustelo,et al.  Transcriptomal profiling of the cellular transformation induced by Rho subfamily GTPases , 2007, Oncogene.

[18]  Lei Wang,et al.  Cell type-specific functions of Rho GTPases revealed by gene targeting in mice. , 2007, Trends in cell biology.

[19]  C. Daub,et al.  BMC Systems Biology , 2007 .

[20]  D. Goodrich,et al.  The retinoblastoma tumor-suppressor gene, the exception that proves the rule , 2006, Oncogene.

[21]  R. Forteza,et al.  Epidermal Growth Factor Receptor Activation by Epidermal Growth Factor Mediates Oxidant-Induced Goblet Cell Metaplasia in Human Airway Epithelium , 2006 .

[22]  P. Höglund.  DNA Damage and Tumor Surveillance: One Trigger for Two Pathways , 2006, Science's STKE.

[23]  Rafael A. Irizarry,et al.  Bioinformatics and Computational Biology Solutions using R and Bioconductor , 2005 .

[24]  B. Hogan,et al.  Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation , 2005, Development.

[25]  M. Hetzel,et al.  Different Effects of Growth Factors on Proliferation and Matrix Production of Normal and Fibrotic Human Lung Fibroblasts , 2005, Lung.

[26]  A. Lin,et al.  Molecular signature of oncogenic ras-induced senescence , 2004, Oncogene.

[27]  Jean YH Yang,et al.  Bioconductor: open software development for computational biology and bioinformatics , 2004, Genome Biology.

[28]  A. Almasan,et al.  Opposing roles of E2Fs in cell proliferation and death , 2004, Cancer biology & therapy.

[29]  H. A. Rogoff,et al.  Life, Death, and E2F: Linking Proliferation Control and DNA Damage Signaling via E2F1 , 2004, Cell cycle.

[30]  S. Lowe,et al.  Reversing Drug Resistance In Vivo , 2004, Cell cycle.

[31]  B. Hogan,et al.  Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm , 2004, Journal of biology.

[32]  Michael F. Olson,et al.  RAS and RHO GTPases in G1-phase cell-cycle regulation , 2004, Nature Reviews Molecular Cell Biology.

[33]  Gordon K Smyth,et al.  Statistical Applications in Genetics and Molecular Biology Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments , 2011 .

[34]  R. Mason,et al.  Keratinocyte growth factor stimulates alveolar type II cell proliferation through the extracellular signal-regulated kinase and phosphatidylinositol 3-OH kinase pathways. , 2004, American journal of respiratory cell and molecular biology.

[35]  T. Möröy,et al.  Miz1 Is Required for Early Embryonic Development during Gastrulation , 2003, Molecular and Cellular Biology.

[36]  Rafael A Irizarry,et al.  Exploration, normalization, and summaries of high density oligonucleotide array probe level data. , 2003, Biostatistics.

[37]  Hiroaki Kitano,et al.  The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models , 2003, Bioinform..

[38]  K. Goss,et al.  VEGF induces airway epithelial cell proliferation in human fetal lung in vitro. , 2001, American journal of physiology. Lung cellular and molecular physiology.

[39]  R. Dickson,et al.  Adhesion-regulated G1 cell cycle arrest in epithelial cells requires the downregulation of c-Myc , 2001, Oncogene.

[40]  D. Hanahan,et al.  The Hallmarks of Cancer , 2000, Cell.

[41]  G. Prendergast,et al.  New Myc-interacting proteins: a second Myc network emerges , 1999, Oncogene.

[42]  A. McMahon,et al.  Sonic hedgehog regulates branching morphogenesis in the mammalian lung , 1998, Current Biology.

[43]  G. Evan,et al.  A matter of life and cell death. , 1998, Science.

[44]  B. Hogan,et al.  Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. , 1997, Development.

[45]  G. Carmichael,et al.  An alternative pathway for gene regulation by Myc , 1997, The EMBO journal.

[46]  J. Brody,et al.  FGF‐1 and FGF‐7 induce distinct patterns of growth and differentiation in embryonic lung epithelium , 1997, Developmental dynamics : an official publication of the American Association of Anatomists.

[47]  B. Lutterbach,et al.  Overexpression of c-Myc and cell immortalization alters c-Myc phosphorylation , 1997, Oncogene.

[48]  B. Hogan,et al.  Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. , 1997, Development.

[49]  A. Stiles,et al.  New insights into lung growth and development , 1996, Current opinion in pediatrics.

[50]  S. R. Hilfer,et al.  Morphogenesis of the lung: control of embryonic and fetal branching. , 1996, Annual review of physiology.

[51]  R. Derynck,et al.  Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor , 1995, Nature.

[52]  J. Rubin,et al.  Keratinocyte growth factor , 1995, Cell biology international.

[53]  Yang Xh,et al.  Overexpression of the E2F-1 transcription factor gene mediates cell transformation. , 1995 .

[54]  T. Sladek,et al.  Overexpression of the E2F-1 transcription factor gene mediates cell transformation. , 1995, Gene expression.

[55]  D. Madtes,et al.  Expression of transforming growth factor-alpha and epidermal growth factor receptor is increased following bleomycin-induced lung injury in rats. , 1994, American journal of respiratory cell and molecular biology.

[56]  B. Groner,et al.  NIH/3T3 cells transformed with the activated erbB-2 oncogene can be phenotypically reverted by a kinase deficient, dominant negative erbB-2 variant , 1994, Molecular and Cellular Endocrinology.

[57]  J. Whitsett,et al.  Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice. , 1994, The Journal of clinical investigation.

[58]  D. Warburton,et al.  Epidermal growth factor transcription, translation, and signal transduction by rat type II pneumocytes in culture. , 1992, American journal of respiratory cell and molecular biology.

[59]  J. Meldolesi,et al.  Transmembrane signalling at epidermal growth factor receptors overexpressed in NIH 3T3 cells. Phosphoinositide hydrolysis, cytosolic Ca2+ increase and alkalinization correlate with epidermal-growth-factor-induced cell proliferation. , 1988, The Biochemical journal.

[60]  M. Abercrombie,et al.  Fibroblasts , 1978, Journal of clinical pathology. Supplement.