TLR7 is expressed by support cells, but not sensory neurons, in ganglia

[1]  D. Spray,et al.  Emerging importance of satellite glia in nervous system function and dysfunction , 2020, Nature Reviews Neuroscience.

[2]  J. Milbrandt,et al.  Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia , 2020, Nature Communications.

[3]  P. Loke,et al.  Identification of a nerve-associated, lung-resident interstitial macrophage subset with distinct localization and immunoregulatory properties , 2020, Science Immunology.

[4]  A. Basbaum,et al.  Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain , 2020, Nature Communications.

[5]  Jia Liu,et al.  Toll-Like Receptor 7 Activation Enhances CD8+ T Cell Effector Functions by Promoting Cellular Glycolysis , 2019, Front. Immunol..

[6]  M. Hanani,et al.  Nitric oxide as a messenger between neurons and satellite glial cells in dorsal root ganglia , 2019, Glia.

[7]  A. Basu,et al.  Japanese Encephalitis Virus‐induced let‐7a/b interacted with the NOTCH‐TLR7 pathway in microglia and facilitated neuronal death via caspase activation , 2019, Journal of neurochemistry.

[8]  P. Devillier,et al.  The Role of Toll-Like Receptors in the Production of Cytokines by Human Lung Macrophages , 2018, Journal of Innate Immunity.

[9]  H. Eng,et al.  Differences in TLR7/8 activation between monocytes and macrophages. , 2018, Biochemical and biophysical research communications.

[10]  J. Obst,et al.  The Evolving Dialogue of Microglia and Neurons in Alzheimer’s Disease: Microglia as Necessary Transducers of Pathology , 2018, Neuroscience.

[11]  R. Uddman,et al.  Substance P represents a novel first‐line defense mechanism in the nose , 2018, The Journal of allergy and clinical immunology.

[12]  M. Shlomchik,et al.  Tissue‐Resident Macrophages Are Locally Programmed for Silent Clearance of Apoptotic Cells , 2017, Immunity.

[13]  Xinzhong Dong,et al.  Distinct and common expression of receptors for inflammatory mediators in vagal nodose versus jugular capsaicin-sensitive/TRPV1-positive neurons detected by low input RNA sequencing , 2017, PloS one.

[14]  A. Osterhaus,et al.  Satellite glial cells in human trigeminal ganglia have a broad expression of functional Toll‐like receptors , 2017, European journal of immunology.

[15]  Yu-Qiu Zhang,et al.  Pain regulation by non-neuronal cells and inflammation , 2016, Science.

[16]  A. Fryer,et al.  Human and Mouse Eosinophils Have Antiviral Activity against Parainfluenza Virus. , 2016, American journal of respiratory cell and molecular biology.

[17]  J. Connolly,et al.  TLR7 and TLR9 ligands regulate antigen presentation by macrophages. , 2016, International immunology.

[18]  Jh Bennett,et al.  The expression of Toll-like receptor 4, 7 and co-receptors in neurochemical sub-populations of rat trigeminal ganglion sensory neurons , 2015, Neuroscience.

[19]  A. Fryer,et al.  Interleukin-1β mediates virus-induced m2 muscarinic receptor dysfunction and airway hyperreactivity. , 2014, American journal of respiratory cell and molecular biology.

[20]  S. Jung,et al.  Imiquimod induces a Toll-like receptor 7-independent increase in intracellular calcium via IP(3) receptor activation. , 2014, Biochemical and biophysical research communications.

[21]  Zhen-Zhong Xu,et al.  Extracellular MicroRNAs Activate Nociceptor Neurons to Elicit Pain via TLR7 and TRPA1 , 2014, Neuron.

[22]  R. Dahl,et al.  Mapping of TLR5 and TLR7 in central and distal human airways and identification of reduced TLR expression in severe asthma , 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[23]  M. Belvisi,et al.  Harvesting, Isolation, and Functional Assessment of Primary Vagal Ganglia Cells , 2013, Current protocols in pharmacology.

[24]  D. Hwang,et al.  Contribution of Macrophages to Enhanced Regenerative Capacity of Dorsal Root Ganglia Sensory Neurons by Conditioning Injury , 2013, The Journal of Neuroscience.

[25]  A. Fryer,et al.  Toll-like receptor 7 rapidly relaxes human airways. , 2013, American journal of respiratory and critical care medicine.

[26]  Chiung-Ya Chen,et al.  TLR7 Negatively Regulates Dendrite Outgrowth through the Myd88–c-Fos–IL-6 Pathway , 2013, The Journal of Neuroscience.

[27]  A. Fryer,et al.  Toll-like receptor-2/6 and Toll-like receptor-9 agonists suppress viral replication but not airway hyperreactivity in guinea pigs. , 2013, American journal of respiratory cell and molecular biology.

[28]  S. Lehnardt,et al.  Extracellularly Delivered Single-Stranded Viral RNA Causes Neurodegeneration Dependent on TLR7 , 2012, The Journal of Immunology.

[29]  R. Malenka,et al.  An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration , 2012, Nature Neuroscience.

[30]  R. Ritter,et al.  Changes in microglial activation within the hindbrain, nodose ganglia, and the spinal cord following subdiaphragmatic vagotomy , 2012, Neuroscience Letters.

[31]  M. Giustetto,et al.  Synaptic Pruning by Microglia Is Necessary for Normal Brain Development , 2011, Science.

[32]  A. Fryer,et al.  Role of TNF‐α in virus‐induced airway hyperresponsiveness and neuronal M2 muscarinic receptor dysfunction , 2011, British journal of pharmacology.

[33]  J. Cohen,et al.  Painful Pathways Induced by TLR Stimulation of Dorsal Root Ganglion Neurons , 2011, The Journal of Immunology.

[34]  M. Simon,et al.  Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons , 2011, Proceedings of the National Academy of Sciences.

[35]  A. Fryer,et al.  Toll-like receptor 7 agonists are potent and rapid bronchodilators in guinea pigs. , 2011, The Journal of allergy and clinical immunology.

[36]  S. Akira,et al.  Toll-like receptor 7 is not necessary for retroviral neuropathogenesis but does contribute to virus-induced neuroinflammation , 2011, Journal of NeuroVirology.

[37]  Zhen-Zhong Xu,et al.  Toll-like receptor 7 mediates pruritus , 2010, Nature Neuroscience.

[38]  S. Janssens,et al.  Toll‐like receptor expression in the peripheral nerve , 2010, Glia.

[39]  B. Williams,et al.  TLR7 Is Involved in Sequence-Specific Sensing of Single-Stranded RNAs in Human Macrophages1 , 2008, The Journal of Immunology.

[40]  J. Vasilakos,et al.  Comparison of human B cell activation by TLR7 and TLR9 agonists , 2008, BMC Immunology.

[41]  Y. Chen,et al.  Neuronal somatic ATP release triggers neuron–satellite glial cell communication in dorsal root ganglia , 2007, Proceedings of the National Academy of Sciences.

[42]  C. Sommer,et al.  Intraneural injection of interleukin-1β and tumor necrosis factor-alpha into rat sciatic nerve at physiological doses induces signs of neuropathic pain , 2005, Pain.

[43]  M. Nishimura,et al.  Tissue-specific mRNA expression profiles of human toll-like receptors and related genes. , 2005, Biological & pharmaceutical bulletin.

[44]  Shizuo Akira,et al.  Toll-like receptor signalling , 2004, Nature Reviews Immunology.

[45]  N. Van Rooijen,et al.  Role of macrophages in virus-induced airway hyperresponsiveness and neuronal M2 muscarinic receptor dysfunction. , 2004, American Journal of Physiology - Lung cellular and Molecular Physiology.

[46]  Akiko Iwasaki,et al.  Recognition of single-stranded RNA viruses by Toll-like receptor 7. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[47]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[48]  Stephen T Holgate,et al.  Community study of role of viral infections in exacerbations of asthma in 9-11 year old children , 1995, BMJ.

[49]  J. Nadel,et al.  Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection. , 1976, The American review of respiratory disease.