Antibody to cytomegalovirus in patients with Sjögren's syndrome. As determined by an enzyme-linked immunosorbent assay.

By use of enzyme-lined immunosorbent assay (ELISA), patients with Sjögren's syndrome were found to have levels of serum IgG antibody to cytomegalovirus twice those of matched control subjects, and IgM antibody levels which were three times as high. It may be relevant that features of cytomegalovirus infection are similar to those of Sjögren's syndrome.

[1]  H. Kangro.  Evaluation of a radioimmunoassay for IgM-class antibodies against cytomegalovirus. , 1980, British journal of experimental pathology.

[2]  A. Vaheri,et al.  Rheumatoid factor in acute viral infections: interference with determination of IgM, IgG, and IgA antibodies in an enzyme immunoassay. , 1980, The Journal of infectious diseases.

[3]  T. Ziegler,et al.  Solid-phase enzyme immunoassay for determination of antibodies to cytomegalovirus , 1980, Journal of clinical microbiology.

[4]  A. Fauci,et al.  Immunoregulation in Sjögren's syndrome: influence of serum factors on T-cell subpopulations. , 1980, The Journal of clinical investigation.

[5]  A. Ammann,et al.  Immunoglobulin G and M antibodies to pneumococcal polysaccharides detected by enzyme-linked immunosorbent assay , 1980, Infection and immunity.

[6]  H. Moutsopoulos,et al.  Genetic differences between primary and secondary sicca syndrome. , 1979, The New England journal of medicine.

[7]  W. Chia,et al.  Quantitative determination of cytomegalovirus IgG antibody by enzyme-linked immunosorbent assay (ELISA). , 1979, Canadian journal of microbiology.

[8]  H. Moutsopoulos,et al.  Differences in the clinical manifestations of sicca syndrome in the presence and absence of rheumatoid arthritis. , 1979, The American journal of medicine.

[9]  S. S. St. Jeor,et al.  Susceptibility of lymphoblastoid cells to infection with human cytomegalovirus , 1979, Infection and immunity.

[10]  P. Leinikki,et al.  Determination of virus-specific IgM antibodies by using ELISA: elimination of false-positive results with protein A-Sepharose absorption and subsequent IgM antibody assay. , 1978, The Journal of laboratory and clinical medicine.

[11]  R. Hoover,et al.  Increased risk of lymphoma in sicca syndrome. , 1978, Annals of internal medicine.

[12]  R. Jaffe,et al.  Evidence that the malignant lymphoma of Sjögren's syndrome is a monoclonal B-cell neoplasm. , 1978, The New England journal of medicine.

[13]  P. Terasaki,et al.  Relationship of Hla‐Dw3 and Hla‐B8 to Sjögren'S Syndrome , 1978 .

[14]  N. Talal.  Disordered Immunologic Regulation and Autoimmunity , 1976, Birth defects original article series.

[15]  J. Mackenzie,et al.  Resistance to murine cytomegalovirus linked to the major histocompatibility complex of the mouse. , 1977, The Journal of general virology.

[16]  G. Klein,et al.  Antibodies against cytomegalovirus-induced early antigens (CMV-EA) in immunosuppressed renal-allograft recipients. , 1977, Clinical and experimental immunology.

[17]  A. Vogt,et al.  Solid-phase enzyme immunoassay for immunoglobulin M antibodies to cytomegalovirus , 1977, Journal of clinical microbiology.

[18]  F. Rapp,et al.  Human cells transformed in vitro by human cytomegalovirus: tumorigenicity in athymic nude mice. , 1977, Journal of the National Cancer Institute.

[19]  S. S. St. Jeor,et al.  Persistence of cytomegalovirus in human lymphoblasts and peripheral leukocyte cultures , 1977, Infection and immunity.

[20]  E. Tan,et al.  Differentiation and characterization of autoantibodies and their antigens in Sjögren's syndrome. , 1976, Arthritis and rheumatism.

[21]  J. Menezes,et al.  Persistence of CMV genome in lymphoid cells after congenital infection , 1975, Nature.

[22]  A. Voller,et al.  A simple method for detecting antibodies to rubella. , 1975, British journal of experimental pathology.

[23]  E. R. Zimmermann,et al.  Murine tumor induction by cytomegalovirus. , 1975, Oral surgery, oral medicine, and oral pathology.

[24]  S. Silverman,et al.  The oral component of Sjögren's syndrome. , 1975, Oral surgery, oral medicine, and oral pathology.

[25]  N. Cremer,et al.  Immunological and virological studies of cultured labial biopsy cells from patients with Sjögren's syndrome. , 1974, Clinical and Experimental Immunology.

[26]  J. Greenspan,et al.  sjögren's syndrome: a correlation between ocular findings and labial salivary gland histology. , 1974, Transactions - American Academy of Ophthalmology and Otolaryngology. American Academy of Ophthalmology and Otolaryngology.

[27]  J. Greenspan,et al.  The histopathology of Sjögren's syndrome in labial salivary gland biopsies. , 1974, Oral surgery, oral medicine, and oral pathology.

[28]  D. Normansell,et al.  Sjögren's syndrome: hyperviscosity and intermediate complexes. , 1974, Annals of internal medicine.

[29]  E. Engvall,et al.  Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes. , 1972, Journal of immunology.

[30]  J. Nagington.  Cytomegalovirus antibody production in renal transplant patients , 1971, Epidemiology and Infection.

[31]  T. H. Weller.  The cytomegaloviruses: ubiquitous agents with protean clinical manifestations. I. , 1971, The New England journal of medicine.

[32]  B. Johnson,et al.  Immunologic abnormalities induced by postperfusion cytomegalovirus infection. , 1970, Annals of internal medicine.

[33]  P. Diosi,et al.  Latent cytomegalovirus infection in blood donors , 1969, British medical journal.

[34]  H. Bartfeld.  DISTRIBUTION OF RHEUMATOID FACTOR ACTIVITY IN NONRHEUMATOID STATES * , 1969, Annals of the New York Academy of Sciences.

[35]  T. Elsdale,et al.  Brief Report: The Isolation of Cytomegalovirus from Peripheral Blood , 1967 .

[36]  W. Zuelzer,et al.  Gytomegalovirus Infections with Reference to Isolations from Lymph Nodes and Blood.∗ , 1966, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[37]  J. J. Bunim,et al.  SJÖGREN'S SYNDROME: A Clinical, Pathological, and Serological Study of Sixty-two Cases , 1965, Medicine.

[38]  Margaret G. Smith.  Propagation in Tissue Cultures of a Cytopathogenic Virus from Human Salivary Gland Virus (SGV) Disease.∗ , 1956, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.