Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers - pre-clinical and clinical investigations

[1]  T. Arndt Trait-Marker , 2019, Springer Reference Medizin.

[2]  D. Skuse,et al.  ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties , 2017, Molecular Psychiatry.

[3]  J. Leza,et al.  Paliperidone reverts Toll-like receptor 3 signaling pathway activation and cognitive deficits in a maternal immune activation mouse model of schizophrenia , 2017, Neuropharmacology.

[4]  Zhengwei Li,et al.  A liminal stage after predictive testing for Huntington disease , 2017, Journal of Medical Genetics.

[5]  Y. Kuperman,et al.  High-fat diet exacerbates cognitive rigidity and social deficiency in the BTBR mouse model of autism , 2017, Neuroscience.

[6]  Celso Arango,et al.  Oxidative Stress and Inflammation in Early Onset First Episode Psychosis: A Systematic Review and Meta-Analysis , 2017, The international journal of neuropsychopharmacology.

[7]  T. Werge,et al.  Risk of Psychiatric Disorders Among Individuals With the 22q11.2 Deletion or Duplication: A Danish Nationwide, Register-Based Study , 2017, JAMA psychiatry.

[8]  C. Schaaf,et al.  Autism genetics – an overview , 2017, Prenatal diagnosis.

[9]  T. Bale The placenta and neurodevelopment: sex differences in prenatal vulnerability , 2016, Dialogues in clinical neuroscience.

[10]  M. McCarthy Sex differences in the developing brain as a source of inherent risk , 2016, Dialogues in clinical neuroscience.

[11]  H. Akça,et al.  miR-181b-5p, miR-195-5p and miR-301a-3p are related with treatment resistance in schizophrenia , 2016, Psychiatry Research.

[12]  K. Fukunaga,et al.  Functional Genomic Analyses Identify Pathways Dysregulated in Animal Model of Autism , 2016, CNS neuroscience & therapeutics.

[13]  A. Depino,et al.  Postnatal behavioral and inflammatory alterations in female pups prenatally exposed to valproic acid , 2016, Psychoneuroendocrinology.

[14]  Hassan Rahmoune,et al.  Neuroimmune biomarkers in schizophrenia , 2016, Schizophrenia Research.

[15]  Andreia M. Silva,et al.  Circulating extracellular vesicles: Their role in tissue repair and regeneration. , 2016, Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.

[16]  R. Hill Sex differences in animal models of schizophrenia shed light on the underlying pathophysiology , 2016, Neuroscience & Biobehavioral Reviews.

[17]  E. Vasar,et al.  Antipsychotic Treatment Reduces Indices of Oxidative Stress in First-Episode Psychosis Patients , 2016, Oxidative medicine and cellular longevity.

[18]  U. Meyer,et al.  Prenatal immune activation causes hippocampal synaptic deficits in the absence of overt microglia anomalies , 2016, Brain, Behavior, and Immunity.

[19]  A. Sawa,et al.  Utility and validity of DISC1 mouse models in biological psychiatry , 2016, Neuroscience.

[20]  Yong-hui Jiang,et al.  Monogenic mouse models of autism spectrum disorders: Common mechanisms and missing links , 2016, Neuroscience.

[21]  D. Newburg,et al.  Evaluation of Intestinal Function in Children With Autism and Gastrointestinal Symptoms , 2016, Journal of pediatric gastroenterology and nutrition.

[22]  F. Rossi,et al.  Autistic-Like Traits and Cerebellar Dysfunction in Purkinje Cell PTEN Knock-Out Mice , 2016, Neuropsychopharmacology.

[23]  Dorota Frydecka,et al.  Reduced number of peripheral natural killer cells in schizophrenia but not in bipolar disorder , 2016, Brain, Behavior, and Immunity.

[24]  F. Middleton,et al.  Salivary miRNA profiles identify children with autism spectrum disorder, correlate with adaptive behavior, and implicate ASD candidate genes involved in neurodevelopment , 2016, BMC Pediatrics.

[25]  G. Juckel,et al.  Flow cytometric characterization of microglia in the offspring of PolyI:C treated mice , 2016, Brain Research.

[26]  J. C. Morales-Medina,et al.  Neuronal and brain morphological changes in animal models of schizophrenia , 2016, Behavioural Brain Research.

[27]  Hyunju Kim,et al.  The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring , 2016, Science.

[28]  F. Zhang,et al.  Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2 , 2016, Nature.

[29]  D. Collier,et al.  Advances in the genetics of schizophrenia: toward a network and pathway view for drug discovery , 2016, Annals of the New York Academy of Sciences.

[30]  G. Rumbaugh,et al.  Prioritizing the development of mouse models for childhood brain disorders , 2016, Neuropharmacology.

[31]  M. Cuénod,et al.  Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia , 2016, PloS one.

[32]  Hyoung-Ah Kim,et al.  Aberrant IgG isotype generation in mice with abnormal behaviors , 2016, Journal of immunotoxicology.

[33]  Alan S. Brown,et al.  Maternal Immune Activation Leads to Selective Functional Deficits in Offspring Parvalbumin Interneurons , 2015, Molecular Psychiatry.

[34]  Alessandra Bertoldo,et al.  Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [(11)C]PBR28 PET Brain Imaging Study. , 2015, The American journal of psychiatry.

[35]  S. Ivanova,et al.  Serum Glutathione in Patients with Schizophrenia in Dynamics of Antipsychotic Therapy , 2015, Bulletin of Experimental Biology and Medicine.

[36]  W. Wood,et al.  Hippocampal Transcriptomic and Proteomic Alterations in the BTBR Mouse Model of Autism Spectrum Disorder , 2015, Front. Physiol..

[37]  Zhandong Liu,et al.  Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders , 2015, Molecular Brain.

[38]  A. Brownell,et al.  Loss of Metabotropic Glutamate Receptor 5 Function on Peripheral Benzodiazepine Receptor in Mice Prenatally Exposed to LPS , 2015, PloS one.

[39]  A. Dunaevsky,et al.  Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders , 2015, Brain, Behavior, and Immunity.

[40]  M. McCarthy,et al.  Surprising origins of sex differences in the brain , 2015, Hormones and Behavior.

[41]  L. Pacini,et al.  Autism Spectrum Disorders: Translating human deficits into mouse behavior , 2015, Neurobiology of Learning and Memory.

[42]  Hongwei Shen,et al.  miR-101a and miR-30b contribute to inflammatory cytokine-mediated β-cell dysfunction , 2015, Laboratory Investigation.

[43]  David J. Anderson,et al.  Automated measurement of mouse social behaviors using depth sensing, video tracking, and machine learning , 2015, Proceedings of the National Academy of Sciences.

[44]  M. Maes,et al.  Oxidative stress in drug naïve first episode psychosis and antioxidant effects of risperidone. , 2015, Journal of psychiatric research.

[45]  Hong Jiang,et al.  miRNA profiling in autism spectrum disorder in China , 2015, Genomics data.

[46]  P. Legendre,et al.  Maternal immune activation evoked by polyinosinic:polycytidylic acid does not evoke microglial cell activation in the embryo , 2015, Front. Cell. Neurosci..

[47]  J. Homberg,et al.  Elevated microRNA-181c and microRNA-30d levels in the enlarged amygdala of the valproic acid rat model of autism , 2015, Neurobiology of Disease.

[48]  Li-yi Zhang,et al.  MicroRNA-7/Shank3 axis involved in schizophrenia pathogenesis , 2015, Journal of Clinical Neuroscience.

[49]  M. Maes,et al.  High predictive value of immune-inflammatory biomarkers for schizophrenia diagnosis and association with treatment resistance , 2015, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

[50]  Yan Shen,et al.  Detection of circulating miRNA levels in schizophrenia. , 2015, The American journal of psychiatry.

[51]  K. Xia,et al.  Investigation of Gene Regulatory Networks Associated with Autism Spectrum Disorder Based on MiRNA Expression in China , 2015, PloS one.

[52]  J. Crawley,et al.  Behavioral and Neuroanatomical Phenotypes in Mouse Models of Autism , 2015, Neurotherapeutics.

[53]  T. Takano Role of Microglia in Autism: Recent Advances , 2015, Developmental Neuroscience.

[54]  R. Citraro,et al.  Peroxisome proliferator-activated receptor alpha plays a crucial role in behavioral repetition and cognitive flexibility in mice , 2015, Molecular metabolism.

[55]  Sabine Bahn,et al.  The Potential of Immune Biomarkers to Advance Personalized Medicine Approaches for Schizophrenia , 2015, The Journal of nervous and mental disease.

[56]  D. Rujescu,et al.  The promise of biological markers for treatment response in first-episode psychosis: a systematic review. , 2015, Schizophrenia bulletin.

[57]  C. J. Machado,et al.  Maternal Immune Activation in Nonhuman Primates Alters Social Attention in Juvenile Offspring , 2015, Biological Psychiatry.

[58]  R. Sankar,et al.  Autism-Like Behavior in BTBR Mice Is Improved by Electroconvulsive Therapy , 2015, Neurotherapeutics.

[59]  Steffen Jung,et al.  Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli. , 2015, Immunity.

[60]  Hyoung-Ah Kim,et al.  Altered Expression Levels of Neurodevelopmental Proteins in Fetal Brains of BTBR T+tf/J Mice with Autism-Like Behavioral Characteristics , 2015, Journal of toxicology and environmental health. Part A.

[61]  Laura R. Fenlon,et al.  Formation of functional areas in the cerebral cortex is disrupted in a mouse model of autism spectrum disorder , 2015, Neural Development.

[62]  W. Niu,et al.  A preliminary analysis of microRNA as potential clinical biomarker for schizophrenia , 2015, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[63]  R. Murray,et al.  Cortisol and Inflammatory Biomarkers Predict Poor Treatment Response in First Episode Psychosis , 2015, Schizophrenia bulletin.

[64]  L. Ricceri,et al.  Prenatal Exposure to a Common Organophosphate Insecticide Delays Motor Development in a Mouse Model of Idiopathic Autism , 2015, PloS one.

[65]  Alon Chen,et al.  Determining the role of microRNAs in psychiatric disorders , 2015, Nature Reviews Neuroscience.

[66]  Eunjoon Kim,et al.  Shank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit , 2015, Front. Cell. Neurosci..

[67]  W. Niu,et al.  Aberrant microRNA expression in peripheral plasma and mononuclear cells as specific blood-based biomarkers in schizophrenia patients , 2015, Journal of Clinical Neuroscience.

[68]  Jae-Seung Hong,et al.  Enhancement of Short-Term Memory by Methyl-6-(Phenylethynyl)-Pyridine in the BTBR T+tf/J Mouse Model of Autism Spectrum Disorder , 2015, Endocrinology and metabolism.

[69]  A. Naqvi,et al.  miR-24, miR-30b, and miR-142-3p Regulate Phagocytosis in Myeloid Inflammatory Cells , 2015, The Journal of Immunology.

[70]  Xiaohong Li,et al.  Inflammatory Cytokines: Potential Biomarkers of Immunologic Dysfunction in Autism Spectrum Disorders , 2015, Mediators of inflammation.

[71]  Helena Brentani,et al.  Innate immune response is differentially dysregulated between bipolar disease and schizophrenia , 2015, Schizophrenia Research.

[72]  P. Ashwood,et al.  Inflammatory profiles in the BTBR mouse: How relevant are they to autism spectrum disorders? , 2015, Brain, Behavior, and Immunity.

[73]  Xiaolin Zhu,et al.  The combined role of serotonin and interleukin-6 as biomarker for autism , 2015, Neuroscience.

[74]  Lara S. Collier,et al.  Microglial numbers attain adult levels after undergoing a rapid decrease in cell number in the third postnatal week , 2015, Journal of Neuroimmunology.

[75]  Lei Liu,et al.  Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome , 2015, Cell.

[76]  Alan A. Wilson,et al.  Imaging neuroinflammation in gray and white matter in schizophrenia: an in-vivo PET study with [18F]-FEPPA. , 2015, Schizophrenia bulletin.

[77]  B. Sang,et al.  The roles of cortisol and pro-inflammatory cytokines in assisting the diagnosis of autism spectrum disorder , 2015 .

[78]  M. Scattoni,et al.  Altered functional connectivity networks in acallosal and socially impaired BTBR mice , 2016, Brain Structure and Function.

[79]  M. Maes,et al.  Effects of Risperidone on Cytokine Profile in Drug-Naïve First-Episode Psychosis , 2015, The international journal of neuropsychopharmacology.

[80]  A. Nitta,et al.  Behavioral phenotypes for negative symptoms in animal models of schizophrenia. , 2014, Journal of pharmacological sciences.

[81]  L. Ulloa,et al.  Dopamine mediates vagal modulation of the immune system by electroacupuncture , 2014, Critical Care.

[82]  P. Ashwood,et al.  Change in plasma cytokine levels during risperidone treatment in children with autism. , 2014, Journal of child and adolescent psychopharmacology.

[83]  I. Pogribny,et al.  Cerebellar Oxidative DNA Damage and Altered DNA Methylation in the BTBR T+tf/J Mouse Model of Autism and Similarities with Human Post Mortem Cerebellum , 2014, PloS one.

[84]  A. Weeren,et al.  The risk for behavioural deficits is determined by the maternal immune response to prenatal immune challenge in a neurodevelopmental model , 2014, Brain, Behavior, and Immunity.

[85]  H. Arai,et al.  Significance of measurements of peripheral carbonyl stress markers in a cross-sectional and longitudinal study in patients with acute-stage schizophrenia. , 2014, Schizophrenia bulletin.

[86]  Naveen Dhawan,et al.  Are Attributes of Pregnancy and the Delivery Room Experience Related to Development of Autism? A Review of the Perinatal and Labor Risk Factors and Autism , 2014, International scholarly research notices.

[87]  J. Waddington,et al.  Phenotypic effects of maternal immune activation and early postnatal milieu in mice mutant for the schizophrenia risk gene neuregulin-1 , 2014, Neuroscience.

[88]  R M Henkelman,et al.  Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity , 2014, Molecular Psychiatry.

[89]  M. Itokawa,et al.  Clinical features of schizophrenia with enhanced carbonyl stress. , 2014, Schizophrenia bulletin.

[90]  Stuart Maudsley,et al.  The effects of aging on the BTBR mouse model of autism spectrum disorder , 2014, Front. Aging Neurosci..

[91]  U. Meyer,et al.  Single and combined effects of prenatal immune activation and peripubertal stress on parvalbumin and reelin expression in the hippocampal formation , 2014, Brain, Behavior, and Immunity.

[92]  N. Mori,et al.  Serum microRNA profiles in children with autism , 2014, Molecular Autism.

[93]  P. Lipsky,et al.  Defective PTEN regulation contributes to B cell hyperresponsiveness in systemic lupus erythematosus , 2014, Science Translational Medicine.

[94]  L. Miller-Fleming,et al.  Microglia and inflammation: conspiracy, controversy or control? , 2014, Cellular and Molecular Life Sciences.

[95]  Lin Zhao,et al.  A preliminary analysis of association between the down-regulation of microRNA-181b expression and symptomatology improvement in schizophrenia patients before and after antipsychotic treatment. , 2014, Journal of psychiatric research.

[96]  S. Kapur,et al.  A neurobiological hypothesis for the classification of schizophrenia: type A (hyperdopaminergic) and type B (normodopaminergic). , 2014, The British journal of psychiatry : the journal of mental science.

[97]  A. Guastella,et al.  Cytokine aberrations in autism spectrum disorder: a systematic review and meta-analysis , 2014, Molecular Psychiatry.

[98]  A. Naqvi,et al.  MiRNA-181a regulates Toll-like receptor agonist-induced inflammatory response in human fibroblasts , 2014, Genes and Immunity.

[99]  T. Bale,et al.  Prenatal stress-induced increases in placental inflammation and offspring hyperactivity are male-specific and ameliorated by maternal antiinflammatory treatment. , 2014, Endocrinology.

[100]  H. Kettenmann,et al.  Minocycline rescues decrease in neurogenesis, increase in microglia cytokines and deficits in sensorimotor gating in an animal model of schizophrenia , 2014, Brain, Behavior, and Immunity.

[101]  A. Gadelha,et al.  Peripheral interleukin-2 level is associated with negative symptoms and cognitive performance in schizophrenia , 2014, Physiology & Behavior.

[102]  A. Depino,et al.  Altered Peripheral and Central Inflammatory Responses in a Mouse Model of Autism , 2014, Autism research : official journal of the International Society for Autism Research.

[103]  J. Michálek,et al.  MicroRNA Profiling of Activated and Tolerogenic Human Dendritic Cells , 2014, Mediators of inflammation.

[104]  Xinghui Sun,et al.  Role of miR-181 family in regulating vascular inflammation and immunity. , 2014, Trends in cardiovascular medicine.

[105]  R. Kahn,et al.  Cytokine alterations in first-episode schizophrenia patients before and after antipsychotic treatment , 2014, Schizophrenia Research.

[106]  R. Murray,et al.  Antipsychotic Treatment Resistance in Schizophrenia Associated with Elevated Glutamate Levels but Normal Dopamine Function , 2014, Biological Psychiatry.

[107]  A. Kraneveld,et al.  Intestinal inflammation in a murine model of autism spectrum disorders , 2014, Brain, Behavior, and Immunity.

[108]  J. Leza,et al.  Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia. , 2014, Schizophrenia bulletin.

[109]  U. Meyer Prenatal Poly(I:C) Exposure and Other Developmental Immune Activation Models in Rodent Systems , 2014, Biological Psychiatry.

[110]  Craig S. Miller,et al.  Expression of miR-15/107 Family MicroRNAs in Human Tissues and Cultured Rat Brain Cells , 2014, Genom. Proteom. Bioinform..

[111]  J. M. Ramsey,et al.  Serum proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger syndrome , 2014, Molecular Autism.

[112]  S. Dedeurwaerdere,et al.  Hypolocomotive behaviour associated with increased microglia in a prenatal immune activation model with relevance to schizophrenia , 2014, Behavioural Brain Research.

[113]  T. Möller,et al.  The p53 Transcription Factor Modulates Microglia Behavior through MicroRNA-Dependent Regulation of c-Maf , 2014, The Journal of Immunology.

[114]  G. Zunta-Soares,et al.  Decreased serum TNF-alpha levels in chronic schizophrenia patients on long-term antipsychotics: correlation with psychopathology and cognition , 2014, Psychopharmacology.

[115]  B. Hu,et al.  What We Have Learned about Autism Spectrum Disorder from Valproic Acid , 2013, Pathology research international.

[116]  P. Fusar-Poli,et al.  Antipsychotics' effects on blood levels of cytokines in schizophrenia: A meta-analysis , 2013, Schizophrenia Research.

[117]  Emma L. Burrows,et al.  Decanalization mediating gene-environment interactions in schizophrenia and other psychiatric disorders with neurodevelopmental etiology , 2013, Front. Behav. Neurosci..

[118]  J. M. Ramsey,et al.  Distinct Molecular Phenotypes in Male and Female Schizophrenia Patients , 2013, PloS one.

[119]  C. Harden In Utero Valproate Exposure and Autism: Long Suspected, Finally Proven , 2013, Epilepsy currents.

[120]  M. Riva,et al.  Prenatal versus postnatal maternal factors in the development of infection-induced working memory impairments in mice , 2013, Brain, Behavior, and Immunity.

[121]  R. Hansen,et al.  Increased Anti-Phospholipid Antibodies in Autism Spectrum Disorders , 2013, Mediators of inflammation.

[122]  P. Ashwood,et al.  Inflammatory macrophage phenotype in BTBR T+tf/J mice , 2013, Front. Neurosci..

[123]  Kira S. Sheinerman,et al.  Circulating cell-free microRNA as biomarkers for screening, diagnosis and monitoring of neurodegenerative diseases and other neurologic pathologies , 2013, Front. Cell. Neurosci..

[124]  V. Bolivar,et al.  The BTBR T + tf/J mouse model for autism spectrum disorders–in search of biomarkers , 2013, Behavioural Brain Research.

[125]  Jianxin Shi,et al.  Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs , 2013, Nature Genetics.

[126]  G. Jonakait,et al.  Maternal inflammation promotes fetal microglial activation and increased cholinergic expression in the fetal basal forebrain: role of interleukin-6 , 2013, Pediatric Research.

[127]  Alexander W. Johnson,et al.  Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness , 2013, Proceedings of the National Academy of Sciences.

[128]  Emmette R. Hutchison,et al.  Evidence for miR‐181 involvement in neuroinflammatory responses of astrocytes , 2013, Glia.

[129]  P. Patterson,et al.  Maternal immune activation causes age- and region-specific changes in brain cytokines in offspring throughout development , 2013, Brain, Behavior, and Immunity.

[130]  C. Gonçalves,et al.  Interleukin-6-induced S100B secretion is inhibited by haloperidol and risperidone , 2013, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[131]  V. Stefanović,et al.  Antipsychotics can modulate the cytokine profile in schizophrenia: Attenuation of the type-2 inflammatory response , 2013, Schizophrenia Research.

[132]  S. Rapoport,et al.  RETRACTED: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in the postmortem frontal cortex from schizophrenia patients , 2013, Schizophrenia Research.

[133]  Adam Williams,et al.  The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis. , 2013, Immunity.

[134]  P. Buckley,et al.  Meta-Analysis of Lymphocytes in Schizophrenia: Clinical Status and Antipsychotic Effects , 2013, Biological Psychiatry.

[135]  J. Roder,et al.  Maternal Immune Activation during Gestation Interacts with Disc1 Point Mutation to Exacerbate Schizophrenia-Related Behaviors in Mice , 2013, The Journal of Neuroscience.

[136]  O. Andreassen,et al.  Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia and bipolar disorder , 2013, Schizophrenia Research.

[137]  J. Feldon,et al.  Stress in Puberty Unmasks Latent Neuropathological Consequences of Prenatal Immune Activation in Mice , 2013, Science.

[138]  P. Boksa,et al.  A way forward for research on biomarkers for psychiatric disorders. , 2013, Journal of psychiatry & neuroscience : JPN.

[139]  V. Perry,et al.  Review: Activation patterns of microglia and their identification in the human brain , 2013, Neuropathology and applied neurobiology.

[140]  M. Cairns,et al.  Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia , 2013, Molecular Psychiatry.

[141]  E. Chan,et al.  Regulation of TLR2-Mediated Tolerance and Cross-Tolerance through IRAK4 Modulation by miR-132 and miR-212 , 2013, The Journal of Immunology.

[142]  R. Blakely,et al.  A dialogue between the immune system and brain, spoken in the language of serotonin. , 2013, ACS chemical neuroscience.

[143]  Jingping Zhao,et al.  Changes in pro-inflammatory cytokines and body weight during 6-month risperidone treatment in drug naïve, first-episode schizophrenia , 2013, Psychopharmacology.

[144]  Yasuomi Ouchi,et al.  Microglial activation in young adults with autism spectrum disorder. , 2013, JAMA psychiatry.

[145]  A. El-Ansary,et al.  Lipid mediators in plasma of autism spectrum disorders , 2012, Lipids in Health and Disease.

[146]  R. Spizzo,et al.  Long non-coding RNAs and cancer: a new frontier of translational research? , 2012, Oncogene.

[147]  Vishva M Dixit,et al.  Inflammasomes and their roles in health and disease. , 2012, Annual review of cell and developmental biology.

[148]  Alan S. Brown Epidemiologic studies of exposure to prenatal infection and risk of schizophrenia and autism , 2012, Developmental neurobiology.

[149]  Z. Hong,et al.  The microRNA miR-181c controls microglia-mediated neuronal apoptosis by suppressing tumor necrosis factor , 2012, Journal of Neuroinflammation.

[150]  L. Al-Ayadhi,et al.  The relationship between the increased frequency of serum antineuronal antibodies and the severity of autism in children. , 2012, European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.

[151]  S. Bilbo,et al.  Sex, glia, and development: Interactions in health and disease , 2012, Hormones and Behavior.

[152]  S. Xiong,et al.  MiR-34a inhibits lipopolysaccharide-induced inflammatory response through targeting Notch1 in murine macrophages. , 2012, Experimental cell research.

[153]  G. Jonakait,et al.  Microglial regulation of cholinergic differentiation in the basal forebrain , 2012, Developmental neurobiology.

[154]  L. Kobzik,et al.  MicroRNA-181b regulates NF-κB-mediated vascular inflammation. , 2012, The Journal of clinical investigation.

[155]  P. Patterson,et al.  Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism , 2012, Brain, Behavior, and Immunity.

[156]  A. Chauhan,et al.  Brain Region-Specific Glutathione Redox Imbalance in Autism , 2012, Neurochemical Research.

[157]  T. Kosten,et al.  Effects of risperidone and haloperidol on superoxide dismutase and nitric oxide in schizophrenia , 2012, Neuropharmacology.

[158]  S. Kannan,et al.  Models of Fetal Brain Injury, Intrauterine Inflammation, and Preterm Birth , 2012, American journal of reproductive immunology.

[159]  Brian A Williams,et al.  Microglia in the Cerebral Cortex in Autism , 2012, Journal of Autism and Developmental Disorders.

[160]  Atsushi Kamiya,et al.  DISC1 Pathway in Brain Development: Exploring Therapeutic Targets for Major Psychiatric Disorders , 2012, Front. Psychiatry.

[161]  Thierry Arnould,et al.  miR-212/132 expression and functions: within and beyond the neuronal compartment , 2012, Nucleic acids research.

[162]  Zhongdang Xiao,et al.  Aberrant expression of serum miRNAs in schizophrenia. , 2012, Journal of psychiatric research.

[163]  B. Bogerts,et al.  Identification of blood-based molecular signatures for prediction of response and relapse in schizophrenia patients , 2012, Translational Psychiatry.

[164]  Robert L. Hendren,et al.  Gene expression in blood is associated with risperidone response in children with autism spectrum disorders , 2011, The Pharmacogenomics Journal.

[165]  C. McDougle,et al.  Risperidone-related improvement of irritability in children with autism is not associated with changes in serum of epidermal growth factor and interleukin-13. , 2011, Journal of child and adolescent psychopharmacology.

[166]  S Baron-Cohen,et al.  Sex-specific serum biomarker patterns in adults with Asperger's syndrome , 2011, Molecular Psychiatry.

[167]  G. Calin,et al.  MicroRNA history: discovery, recent applications, and next frontiers. , 2011, Mutation research.

[168]  Liu Guojun,et al.  Microarray Analysis of Differentially Expressed microRNAs in Allergic Rhinitis , 2011, American journal of rhinology & allergy.

[169]  B. Kirkpatrick,et al.  Meta-Analysis of Cytokine Alterations in Schizophrenia: Clinical Status and Antipsychotic Effects , 2011, Biological Psychiatry.

[170]  L. Al-Ayadhi,et al.  Increased serum osteopontin levels in autistic children: Relation to the disease severity , 2011, Brain, Behavior, and Immunity.

[171]  M. Schwarz,et al.  Inflammatory processes in schizophrenia: a promising neuroimmunological target for the treatment of negative/cognitive symptoms and beyond. , 2011, Pharmacology & therapeutics.

[172]  G. Juckel,et al.  Microglial activation in a neuroinflammational animal model of schizophrenia — a pilot study , 2011, Schizophrenia Research.

[173]  Donna Spiegelman,et al.  Perinatal and Neonatal Risk Factors for Autism: A Comprehensive Meta-analysis , 2011, Pediatrics.

[174]  D. Lawrence,et al.  Aberrant Immune Responses in a Mouse with Behavioral Disorders , 2011, PloS one.

[175]  R. Wank,et al.  Increased prevalence of Chlamydophila DNA in post-mortem brain frontal cortex from patients with schizophrenia , 2011, Schizophrenia Research.

[176]  M. Keshavan,et al.  3-Hydroxykynurenine and clinical symptoms in first-episode neuroleptic-naive patients with schizophrenia. , 2011, The international journal of neuropsychopharmacology.

[177]  H. Hwu,et al.  MicroRNA Expression Aberration as Potential Peripheral Blood Biomarkers for Schizophrenia , 2011, PloS one.

[178]  J. Mattick The central role of RNA in human development and cognition , 2011, FEBS letters.

[179]  S. Pfeffer,et al.  miR-346 Controls Release of TNF-α Protein and Stability of Its mRNA in Rheumatoid Arthritis via Tristetraprolin Stabilization , 2011, PloS one.

[180]  Elaine C. Campbell,et al.  Aberrant NF-KappaB Expression in Autism Spectrum Condition: A Mechanism for Neuroinflammation , 2011, Front. Psychiatry.

[181]  Urs Meyer,et al.  Schizophrenia and Autism: Both Shared and Disorder-Specific Pathogenesis Via Perinatal Inflammation? , 2011, Pediatric Research.

[182]  Janet K. Kern,et al.  Evidence of microglial activation in autism and its possible role in brain underconnectivity , 2011, Neuron glia biology.

[183]  L. Al-Ayadhi,et al.  Increased serum levels of anti-ganglioside M1 auto-antibodies in autistic children: relation to the disease severity , 2011, Journal of Neuroinflammation.

[184]  Fuad G. Gwadry,et al.  Gene and miRNA expression profiles in autism spectrum disorders , 2011, Brain Research.

[185]  P. Penzes,et al.  Dendritic spine pathology in neuropsychiatric disorders , 2011, Nature Neuroscience.

[186]  J. Castro-Fornieles,et al.  Reduced antioxidant defense in early onset first-episode psychosis: a case-control study , 2011, BMC psychiatry.

[187]  G. Ahern 5-HT and the immune system. , 2011, Current opinion in pharmacology.

[188]  F. Cicchetti,et al.  Neuroinflammation is associated with changes in glial mGluR5 expression and the development of neonatal excitotoxic lesions , 2011, Glia.

[189]  Paula Krakowiak,et al.  Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome , 2011, Brain, Behavior, and Immunity.

[190]  R. Hendren,et al.  Improving the prediction of response to therapy in autism , 2010, Neurotherapeutics.

[191]  J. DeWitt,et al.  Environmental risk factors for autism , 2010, Emerging health threats journal.

[192]  C. Ross,et al.  Prenatal Interaction of Mutant DISC1 and Immune Activation Produces Adult Psychopathology , 2010, Biological Psychiatry.

[193]  K. Wright,et al.  Follicular dendritic cell-dependent drug resistance of non-Hodgkin lymphoma involves cell adhesion-mediated Bim down-regulation through induction of microRNA-181a. , 2010, Blood.

[194]  T. Kosten,et al.  Increased serum S100B in never-medicated and medicated schizophrenic patients. , 2010, Journal of psychiatric research.

[195]  Vladimir I. Vladimirov,et al.  MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders , 2010, Schizophrenia Research.

[196]  Gail Mandel,et al.  microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus , 2010, Proceedings of the National Academy of Sciences.

[197]  F. Ginhoux,et al.  Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages , 2010, Science.

[198]  J. Mann,et al.  PET tracers for the peripheral benzodiazepine receptor and uses thereof. , 2010, Drug discovery today.

[199]  T. Dinan,et al.  A systematic review of hypothalamic–pituitary–adrenal axis function in schizophrenia: implications for mortality , 2010, Journal of psychopharmacology.

[200]  L. Garey When cortical development goes wrong: schizophrenia as a neurodevelopmental disease of microcircuits , 2010, Journal of anatomy.

[201]  J. Almeida,et al.  Pharmacogenetics of risperidone therapy in autism: association analysis of eight candidate genes with drug efficacy and adverse drug reactions , 2010, The Pharmacogenomics Journal.

[202]  Carmela Bravaccio,et al.  Alterations of the Intestinal Barrier in Patients With Autism Spectrum Disorders and in Their First-degree Relatives , 2010, Journal of pediatric gastroenterology and nutrition.

[203]  E. Courchesne,et al.  Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism , 2010, Biological Psychiatry.

[204]  Yu Tian Wang,et al.  Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[205]  R. Murray,et al.  Abnormal cortisol awakening response predicts worse cognitive function in patients with first-episode psychosis , 2010, Psychological Medicine.

[206]  D. Matsuzawa,et al.  Enhanced carbonyl stress in a subpopulation of schizophrenia. , 2010, Archives of general psychiatry.

[207]  Takashi Nakamura,et al.  Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis , 2010, Arthritis research & therapy.

[208]  S. Basu,et al.  The immunoregulatory role of dopamine: An update , 2010, Brain, Behavior, and Immunity.

[209]  H. Kraemer,et al.  Moderators, mediators, and other predictors of risperidone response in children with autistic disorder and irritability. , 2010, Journal of child and adolescent psychopharmacology.

[210]  V. Perry,et al.  Microglia in neurodegenerative disease , 2010, Nature Reviews Neurology.

[211]  J. Vázquez-Barquero,et al.  Serotonin transporter polymorphisms and early response to antipsychotic treatment in first episode of psychosis , 2010, Psychiatry Research.

[212]  R. Murray,et al.  Abnormal cortisol levels during the day and cortisol awakening response in first-episode psychosis: The role of stress and of antipsychotic treatment , 2010, Schizophrenia Research.

[213]  T. Dinan,et al.  A systematic review of hypothalamic-pituitary-adrenal axis function in schizophrenia: implications for mortality. , 2010, Journal of psychopharmacology.

[214]  H. Manji,et al.  Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines , 2010, Genome Medicine.

[215]  P. Patterson Immune involvement in schizophrenia and autism: Etiology, pathology and animal models , 2009, Behavioural Brain Research.

[216]  Rudi A. Dierckx,et al.  Neuroinflammation in Schizophrenia-Related Psychosis: A PET Study , 2009, Journal of Nuclear Medicine.

[217]  M. Rapaport,et al.  Persistently increased serum soluble interleukin-2 receptors in continuously ill patients with schizophrenia. , 2009, The international journal of neuropsychopharmacology.

[218]  Sunhee C. Lee,et al.  Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain , 2009, Neuropathology and applied neurobiology.

[219]  Y. Mitsumoto,et al.  Atypical antipsychotics suppress production of proinflammatory cytokines and up-regulate interleukin-10 in lipopolysaccharide-treated mice , 2009, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[220]  Sangita B. Patil,et al.  Elevated immune response in the brain of autistic patients , 2009, Journal of Neuroimmunology.

[221]  J. Gregg,et al.  Altered gene expression and function of peripheral blood natural killer cells in children with autism , 2009, Brain, Behavior, and Immunity.

[222]  Deanna Greenstein,et al.  Autism spectrum disorders and childhood-onset schizophrenia: clinical and biological contributions to a relation revisited. , 2009, Journal of the American Academy of Child and Adolescent Psychiatry.

[223]  E. Olson,et al.  Twist-2 Controls Myeloid Lineage Development and Function , 2008, PLoS biology.

[224]  Paula Krakowiak,et al.  Decreased transforming growth factor beta1 in autism: A potential link between immune dysregulation and impairment in clinical behavioral outcomes , 2008, Journal of Neuroimmunology.

[225]  R. Boellaard,et al.  Microglia Activation in Recent-Onset Schizophrenia: A Quantitative (R)-[11C]PK11195 Positron Emission Tomography Study , 2008, Biological Psychiatry.

[226]  I. Hertz-Picciotto,et al.  Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms , 2008, Autism research : official journal of the International Society for Autism Research.

[227]  Nikolaos Mellios,et al.  A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex. , 2008, Human molecular genetics.

[228]  T. Bale,et al.  Sex-Specific Programming of Offspring Emotionality after Stress Early in Pregnancy , 2008, The Journal of Neuroscience.

[229]  R. Nonneman,et al.  Social approach and repetitive behavior in eleven inbred mouse strains , 2008, Behavioural Brain Research.

[230]  Matej Kastelic,et al.  Acute antipyschotic efficacy and side effects in schizophrenia: Association with serotonin transporter promoter genotypes , 2008, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[231]  Z. Talebizadeh,et al.  Feasibility and relevance of examining lymphoblastoid cell lines to study role of microRNAs in autism , 2008, Autism research : official journal of the International Society for Autism Research.

[232]  Emmanuel Stip,et al.  Inflammatory Cytokine Alterations in Schizophrenia: A Systematic Quantitative Review , 2008, Biological Psychiatry.

[233]  Christoph Schmitz,et al.  Neurons in the fusiform gyrus are fewer and smaller in autism. , 2008, Brain : a journal of neurology.

[234]  R. Passingham,et al.  Is Gray Matter Volume an Intermediate Phenotype for Schizophrenia? A Voxel-Based Morphometry Study of Patients with Schizophrenia and Their Healthy Siblings , 2008, Biological Psychiatry.

[235]  I. Bayazitov,et al.  Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities , 2008, Neuroscience.

[236]  M. Cairns,et al.  Dysregulation of miRNA 181b in the temporal cortex in schizophrenia. , 2008, Human molecular genetics.

[237]  L. Feldcamp,et al.  Biomarkers in Schizophrenia , 2008 .

[238]  S. Stahl,et al.  Neuroscientific basis and practical applications , 2008 .

[239]  K. Mirnics,et al.  Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6 , 2007, The Journal of Neuroscience.

[240]  Takahiro A. Kato,et al.  Risperidone significantly inhibits interferon-γ-induced microglial activation in vitro , 2007, Schizophrenia Research.

[241]  C. Verney,et al.  Entry and Distribution of Microglial Cells in Human Embryonic and Fetal Cerebral Cortex , 2007, Journal of neuropathology and experimental neurology.

[242]  Mark M. Davis,et al.  miR-181a Is an Intrinsic Modulator of T Cell Sensitivity and Selection , 2007, Cell.

[243]  R. Wank,et al.  Associations between Chlamydophila infections, schizophrenia and risk of HLA-A10 , 2007, Molecular Psychiatry.

[244]  J. Xuan,et al.  Response of risperidone treatment may be associated with polymorphisms of HTT gene in Chinese schizophrenia patients , 2007, Neuroscience Letters.

[245]  Jacqueline N. Crawley,et al.  Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains , 2007, Behavioural Brain Research.

[246]  Takahiro A. Kato,et al.  Risperidone significantly inhibits interferon-gamma-induced microglial activation in vitro. , 2007, Schizophrenia research.

[247]  Joel S Parker,et al.  microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder , 2007, Genome Biology.

[248]  C. Beasley,et al.  Calprotectin in microglia from frontal cortex is up‐regulated in schizophrenia: evidence for an inflammatory process? , 2006, The European journal of neuroscience.

[249]  Z. Herman,et al.  Cytokines in schizophrenia and the effects of antipsychotic drugs , 2006, Brain, Behavior, and Immunity.

[250]  David G. Amaral,et al.  Stereological Analysis of Amygdala Neuron Number in Autism , 2006, The Journal of Neuroscience.

[251]  Urs Meyer,et al.  Immunological stress at the maternal–foetal interface: A link between neurodevelopment and adult psychopathology , 2006, Brain, Behavior, and Immunity.

[252]  J. Bolaños,et al.  Glutathione depletion is accompanied by increased neuronal nitric oxide synthase activity , 2006, Neurochemical Research.

[253]  J. Lieberman,et al.  The SNAP-25 gene may be associated with clinical response and weight gain in antipsychotic treatment of schizophrenia , 2005, Neuroscience Letters.

[254]  C. Montresor,et al.  MCP‐1 gene (SCYA2) and schizophrenia: A case‐control association study , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[255]  A. Zimmerman,et al.  Immunity, neuroglia and neuroinflammation in autism , 2005, International review of psychiatry.

[256]  A. Zimmerman,et al.  Neuroglial activation and neuroinflammation in the brain of patients with autism , 2005, Annals of neurology.

[257]  B. Gabryel,et al.  Chlorpromazine and loxapine reduce interleukin-1β and interleukin-2 release by rat mixed glial and microglial cell cultures , 2004, European Neuropsychopharmacology.

[258]  H. Kaiya,et al.  Elevated plasma prostaglandin E2 levels in schizophrenia , 2005, Journal of Neural Transmission.

[259]  D. Perkins,et al.  Expanding the ‘central dogma’: the regulatory role of nonprotein coding genes and implications for the genetic liability to schizophrenia , 2005, Molecular Psychiatry.

[260]  R. Banati,et al.  Visualising microglial activation in vivo , 2002, Glia.

[261]  X. Zhang,et al.  Elevated interleukin-2, interleukin-6 and interleukin-8 serum levels in neuroleptic-free schizophrenia: association with psychopathology , 2002, Schizophrenia Research.

[262]  Yong-Ku Kim,et al.  Relationships between interleukins, neurotransmitters and psychopathology in drug-free male schizophrenics , 2000, Schizophrenia Research.

[263]  Daniel R Weinberger,et al.  To Model a Psychiatric Disorder in Animals: Schizophrenia As a Reality Test , 2000, Neuropsychopharmacology.

[264]  D. Collier,et al.  The serotonin transporter and clozapine response , 2000, Molecular Psychiatry.

[265]  A. Y. Kulberg Immunoglobulins and Antibodies. , 1999, Российский иммунологический журнал.

[266]  P. Falkai,et al.  Evidence for activation of microglia in patients with psychiatric illnesses , 1999, Neuroscience Letters.

[267]  A. Bailey,et al.  A clinicopathological study of autism. , 1998, Brain : a journal of neurology.

[268]  P. Czobor,et al.  Prolactin response to d-fenfluramine challenge test as a predictor of treatment response to haloperidol in acute schizophrenia , 1998, Schizophrenia Research.

[269]  H. Meltzer,et al.  In vivo immunomodulatory effects of clozapine in schizophrenia , 1997, Schizophrenia Research.

[270]  H. Arai,et al.  First-episode neuroleptic-free schizophrenics: Concentrations of monoamines and their metabolites in plasma and their correlations with clinical responses to haloperidol treatment , 1997, Biological Psychiatry.

[271]  B. Halliwell,et al.  Antioxidants in human health and disease. , 1996, Annual review of nutrition.

[272]  J. Calabrese,et al.  Interleukin-2 and interleukin-6 in schizophrenia and mania: effects of neuroleptics and mood stabilizers. , 1995, Journal of psychiatric research.

[273]  H. Y. Meltzer,et al.  Immune‐inflammatory markers in schizophrenia: comparison to normal controls and effects of clozapine , 1994, Acta psychiatrica Scandinavica.

[274]  J. Lieberman,et al.  Plasma homovanillic acid levels in first-episode schizophrenia. Psychopathology and treatment response. , 1994, Archives of general psychiatry.

[275]  D. Weinberger,et al.  Postpubertal Emergence of Hyperresponsiveness to Stress and to Amphetamine after Neonatal Excitotoxic Hippocampal Damage: A Potential Animal Model of Schizophrenia , 1993, Neuropsychopharmacology.

[276]  C. Gillberg,et al.  Glial fibrillary acidic protein in the cerebrospinal fluid of children with autism and other neuropsychiatric disorders , 1993, Biological Psychiatry.

[277]  D. Betcher,et al.  Granulocyte macrophage colony-stimulating factor , 1991, Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses.

[278]  R. Tandon,et al.  Dexamethasone suppression test in schizophrenia: Relationship to symptomatology, ventricular enlargement, and outcome , 1991, Biological Psychiatry.

[279]  R. Warren,et al.  Reduced natural killer cell activity in autism. , 1987, Journal of the American Academy of Child and Adolescent Psychiatry.