Influenza Vaccination Guidelines and Vaccine Sales in Southeast Asia: 2008–2011

Background Southeast Asia is a region with great potential for the emergence of a pandemic influenza virus. Global efforts to improve influenza surveillance in this region have documented the burden and seasonality of influenza viruses and have informed influenza prevention strategies, but little information exists about influenza vaccination guidelines and vaccine sales. Methods To ascertain the existence of influenza vaccine guidelines and define the scope of vaccine sales, we sent a standard three-page questionnaire to the ten member nations of the Association of Southeast Asian Nations. We also surveyed three multinational manufacturers who supply influenza vaccines in the region. Results Vaccine sales in the private sector were <1000 per 100,000 population in the 10 countries. Five countries reported purchasing vaccine for use in the public sector. In 2011, Thailand had the highest combined reported rate of vaccine sales (10,333 per 100,000). In the 10 countries combined, the rate of private sector sales during 2010–2011 (after the A(H1N1)2009pdm pandemic) exceeded 2008 pre-pandemic levels. Five countries (Indonesia, Malaysia, Singapore, Thailand and Vietnam) had guidelines for influenza vaccination but only two were consistent with global guidelines. Four recommended vaccination for health care workers, four for elderly persons, three for young children, three for persons with underlying disease, and two for pregnant women. Conclusions The rate of vaccine sales in Southeast Asia remains low, but there was a positive impact in sales after the A(H1N1)2009pdm pandemic. Low adherence to global vaccine guidelines suggests that more work is needed in the policy arena.

[1]  A. Parant [World population prospects]. , 1990, Futuribles.

[2]  Meeting of the Strategic Advisory Group of Experts on immunization, October 2009--Conclusions and recommendations. , 2010, Biologicals : journal of the International Association of Biological Standardization.

[3]  Mahendra Suhardono,et al.  Establishment of pandemic influenza vaccine production capacity at Bio Farma, Indonesia. , 2011, Vaccine.

[4]  Elio Rossi,et al.  Policy , 2007, Evidence-based Complementary and Alternative Medicine : eCAM.

[5]  M. Kieny,et al.  WHO initiative to increase global and equitable access to influenza vaccine in the event of a pandemic: supporting developing country production capacity through technology transfer. , 2011, Vaccine.

[6]  S. Arifeen,et al.  Neonatal outcomes after influenza immunization during pregnancy: a randomized controlled trial , 2012, Canadian Medical Association Journal.

[7]  K. Ungchusak,et al.  Severe Human Influenza Infections in Thailand: Oseltamivir Treatment and Risk Factors for Fatal Outcome , 2009, PloS one.

[8]  S. Dowell,et al.  Who gets hospitalized for influenza pneumonia in Thailand? Implications for vaccine policy. , 2007, Vaccine.

[9]  松本 慶蔵,et al.  季節性インフルエンザ(Seasonal Influenza)の総括 , 2009 .

[10]  Interim results: state-specific influenza vaccination coverage--United States, August 2010-February 2011. , 2011, MMWR. Morbidity and mortality weekly report.

[11]  T. Music Protecting patients, protecting healthcare workers: a review of the role of influenza vaccination , 2011, International nursing review.

[12]  X. de Radiguès,et al.  Vaccine production capacity for seasonal and pandemic (H1N1) 2009 influenza. , 2009, Vaccine.

[13]  Executive Summary World Urbanization Prospects: The 2018 Revision , 2019 .

[14]  A. Shane Effectiveness of Maternal Influenza Immunization in Mothers and Infants , 2009 .

[15]  D. Commerce Statistical abstract of the United States , 1978 .

[16]  S. Salmaso,et al.  Differences in national influenza vaccination policies across the European Union, Norway and Iceland 2008-2009. , 2010, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

[17]  Kate E. Jones,et al.  Global trends in emerging infectious diseases , 2008, Nature.

[18]  A. Palache Seasonal influenza vaccine provision in 157 countries (2004-2009) and the potential influence of national public health policies. , 2011, Vaccine.

[19]  Meeting of the Strategic Advisory Group of Experts on immunization, April 2012--conclusions and recommendations. , 2016, Releve epidemiologique hebdomadaire.

[20]  P. Bocquier WORLD URBANIZATION PROSPECTS: AN ALTERNATIVE TO THE UN MODEL OF PROJECTION COMPATIBLE WITH URBAN TRANSITION THEORY 1 , 2005 .

[21]  U. C. Bureau Statistical Abstract of the United States , 2004 .