Genome-wide association study identifies eight loci associated with blood pressure
暂无分享,去创建一个
P. O’Reilly | P. Elliott | M. Jarvelin | L. Coin | Toshiko Tanaka | S. Bandinelli | C. Gieger | T. Spector | L. Ferrucci | L. Wain | M. McCarthy | P. Deloukas | E. Zeggini | D. Strachan | M. Tobin | G. Abecasis | N. Freimer | L. Peltonen | A. Paterson | J. Beckmann | D. Altshuler | V. Salomaa | M. Perola | L. Groop | M. Laakso | D. Schlessinger | F. Collins | S. Bergmann | M. Boehnke | S. Heath | P. Burton | N. Samani | W. McArdle | J. Webster | Morris J. Brown | G. Lathrop | J. Connell | A. Dominiczak | P. Munroe | S. Newhouse | C. Wallace | M. Caulfield | M. Farrall | R. Bergman | H. Völzke | S. Eyheramendy | P. Vineis | P. Scheet | G. Zhai | E. Lakatta | T. Meitinger | H. Wichmann | M. Uda | D. Siscovick | D. Grobbee | I. Gut | J. Peden | M. Sandhu | H. Snieder | P. Harst | L. Scott | K. Mohlke | L. Bonnycastle | C. Willer | H. Stringham | A. Jackson | T. Valle | J. Tuomilehto | K. Elliott | B. Voight | S. Kathiresan | O. Melander | C. Newton-Cheh | P. Nilsson | M. Orho-Melander | A. Döring | A. Pfeufer | T. Illig | D. Hadley | G. Berglund | P. Jousilahti | D. Zélénika | A. Syvänen | R. Luben | N. Wareham | A. Hamsten | V. Mooser | F. Ricceri | N. Soranzo | C. O’Donnell | M. Bots | G. Matullo | G. Homuth | A. Teumer | U. Völker | R. Elosua | H. Watkins | J. Kooner | I. Barroso | T. Johnson | P. Vollenweider | G. Waeber | P. Galan | S. Hercberg | R. Clarke | A. Goel | J. Luan | S. Felix | N. Forouhi | J. Kuusisto | J. Chambers | P. van der Harst | F. Zhang | S. Schwartz | M. Numans | S. Sanna | A. Scuteri | S. Najjar | Mario A. Morken | P. Meneton | R. Loos | K. Khaw | A. Hartikainen | A. Pouta | J. Zhao | M. Bochud | G. Navis | R. Lorbeer | J. Marrugat | Y. Schouw | M. Dörr | T. Reffelmann | R. Rettig | S. Bingham | Gabriel J Crawford | F. Ernst | D. Waterworth | S. Guarrera | S. Panico | Y. T. van der Schouw | N. Onland-Moret | Vesela Gateva | Konstantinos Papadakis | S. Polidoro | G. Lucas | N. Lim | K. Song | Xin Yuan | A. Allione | Alessandra Di Gregorio | V. Romanazzi | C. Sacerdote | E. Org | I. Subirana | P. Jong | W. H. Gilst | U. Seedorf | G. Tognoni | F. Williams | C. Uiterwaal | M. Laan | P. D. de Jong | A. di Gregorio | W. V. van Gilst | Diana Zeleneka | R. Elosúa | Feng Zhang
[1] Andrew D. Johnson,et al. Genome-wide association study of blood pressure and hypertension , 2009, Nature Genetics.
[2] D. Levy,et al. Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure , 2009, Nature Genetics.
[3] D. Postma,et al. Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction , 2009, Nature Genetics.
[4] Christian Gieger,et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation , 2009, Nature Genetics.
[5] T. Kataoka,et al. Multiple roles of phosphoinositide-specific phospholipase C isozymes. , 2008, BMB reports.
[6] Philippe Froguel,et al. Common genetic variation near MC4R is associated with waist circumference and insulin resistance , 2008, Nature Genetics.
[7] Subhajyoti De,et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity , 2008, Nature Genetics.
[8] Nilesh J Samani,et al. Common Variants in Genes Underlying Monogenic Hypertension and Hypotension and Blood Pressure in the General Population , 2008, Hypertension.
[9] M. Daly,et al. Estimation of the multiple testing burden for genomewide association studies of nearly all common variants , 2008, Genetic epidemiology.
[10] Hongyu Zhao,et al. Rare independent mutations in renal salt handling genes contribute to blood pressure variation , 2008, Nature Genetics.
[11] David S Sanders,et al. Newly identified genetic risk variants for celiac disease related to the immune response , 2008, Nature Genetics.
[12] M. McCarthy,et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes , 2008, Nature Genetics.
[13] Vincent Mooser,et al. The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome , 2008, BMC cardiovascular disorders.
[14] Stefan Lorkowski,et al. Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. , 2008, Human molecular genetics.
[15] Qiang Zhou,et al. Mutation of the HEXIM1 Gene Results in Defects During Heart and Vascular Development Partly Through Downregulation of Vascular Endothelial Growth Factor , 2008, Circulation research.
[16] N. Alp,et al. Endothelium-Specific GTP Cyclohydrolase I Overexpression Attenuates Blood Pressure Progression in Salt-Sensitive Low-Renin Hypertension , 2008, Circulation.
[17] P. Elliott,et al. Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides , 2008, Nature Genetics.
[18] Dolores Corella,et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans , 2008, Nature Genetics.
[19] Daniel Levy,et al. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness , 2007, BMC Medical Genetics.
[20] D. Lu,et al. A meta-analysis of association between C677T polymorphism in the methylenetetrahydrofolate reductase gene and hypertension , 2007, European Journal of Human Genetics.
[21] D. Lane,et al. HEXIM1 and the Control of Transcription Elongation: From Cancer and Inflammation to AIDS and Cardiac Hypertrophy , 2007, Cell cycle.
[22] R. A. Bailey,et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes , 2007, Nature Genetics.
[23] P. Donnelly,et al. A new multipoint method for genome-wide association studies by imputation of genotypes , 2007, Nature Genetics.
[24] Simon C. Potter,et al. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls , 2007, Nature.
[25] Marcia M. Nizzari,et al. Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels , 2007, Science.
[26] G. Abecasis,et al. A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants , 2007, Science.
[27] M. Laakso,et al. Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion , 2007, Diabetologia.
[28] D. Nebert,et al. The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis , 2006, Nature Reviews Cancer.
[29] B. Charreau,et al. The Adaptor Molecule Lnk Negatively Regulates Tumor Necrosis Factor-α-dependent VCAM-1 Expression in Endothelial Cells through Inhibition of the ERK1 and -2 Pathways* , 2006, Journal of Biological Chemistry.
[30] G. Abecasis,et al. Heritability of Cardiovascular and Personality Traits in 6,148 Sardinians , 2006, PLoS genetics.
[31] S. Nishikawa,et al. Microarray analysis of PDGFR alpha+ populations in ES cell differentiation culture identifies genes involved in differentiation of mesoderm and mesenchyme including ARID3b that is essential for development of embryonic mesenchymal cells. , 2006, Developmental biology.
[32] A. El-Sohemy,et al. Coffee, CYP1A2 genotype, and risk of myocardial infarction. , 2006, JAMA.
[33] J. Pritchard,et al. A Map of Recent Positive Selection in the Human Genome , 2006, PLoS biology.
[34] M. Tobin,et al. Association of WNK1 Gene Polymorphisms and Haplotypes With Ambulatory Blood Pressure in the General Population , 2005, Circulation.
[35] Nuala A Sheehan,et al. Adjusting for treatment effects in studies of quantitative traits: antihypertensive therapy and systolic blood pressure , 2005, Statistics in medicine.
[36] P. Donnelly,et al. A Fine-Scale Map of Recombination Rates and Hotspots Across the Human Genome , 2005, Science.
[37] C. Gieger,et al. KORA-gen - Resource for Population Genetics, Controls and a Broad Spectrum of Disease Phenotypes , 2005 .
[38] N. Samani,et al. Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. , 2005, Human molecular genetics.
[39] S. Vatner. FGF induces hypertrophy and angiogenesis in hibernating myocardium. , 2005, Circulation research.
[40] F. Kronenberg,et al. Association of the 103I MC4R allele with decreased body mass in 7937 participants of two population based surveys , 2005, Journal of Medical Genetics.
[41] U. John,et al. Study of Health in Pomerania (SHIP): A health examination survey in an east German region: Objectives and design , 2005, Sozial- und Präventivmedizin.
[42] Mark I. McCarthy,et al. Early Life Factors and Blood Pressure at Age 31 Years in the 1966 Northern Finland Birth Cohort , 2004, Hypertension.
[43] N. Vaziri,et al. Oxidative stress, renal infiltration of immune cells, and salt-sensitive hypertension: all for one and one for all. , 2004, American journal of physiology. Renal physiology.
[44] D. Grobbee,et al. The Atherosclerosis Risk in Young Adults (ARYA) study: Rationale and design , 2002, European Journal of Epidemiology.
[45] E. Riboli,et al. Prospect-EPIC Utrecht: Study design and characteristics of the cohort population , 2004, European Journal of Epidemiology.
[46] Mattijs E. Numans,et al. The Utrecht Health Project: Optimization of routine healthcare data for research , 2004, European Journal of Epidemiology.
[47] C. Longui,et al. P450c17 deficiency in Brazilian patients: biochemical diagnosis through progesterone levels confirmed by CYP17 genotyping. , 2003, The Journal of clinical endocrinology and metabolism.
[48] Paolo Vineis,et al. A Molecular Epidemiology Project on Diet and Cancer: The Epic-Italy Prospective Study. Design and Baseline Characteristics of Participants , 2003, Tumori.
[49] G. Fink,et al. Gene Transfer of Human Guanosine 5′-Triphosphate Cyclohydrolase I Restores Vascular Tetrahydrobiopterin Level and Endothelial Function in Low Renin Hypertension , 2003, Circulation.
[50] Nilesh Samani,et al. Genome-wide mapping of human loci for essential hypertension , 2003, The Lancet.
[51] Guilbert Jj. The world health report 2002 - reducing risks, promoting healthy life. , 2003 .
[52] R. Collins,et al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies , 2002, The Lancet.
[53] Majid Ezzati,et al. For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group , 2022 .
[54] Jiang He,et al. Primary prevention of hypertension: clinical and public health advisory from The National High Blood Pressure Education Program. , 2002, JAMA.
[55] Hans L Hillege,et al. Urinary Albumin Excretion Predicts Cardiovascular and Noncardiovascular Mortality in General Population , 2002, Circulation.
[56] Masafumi Watanabe,et al. Regulation of smooth muscle cell differentiation by AT-rich interaction domain transcription factors Mrf2alpha and Mrf2beta. , 2002, Circulation research.
[57] T. Pawson,et al. Cytokine Signaling and Hematopoietic Homeostasis Are Disrupted in Lnk-deficient Mice , 2002, The Journal of experimental medicine.
[58] Sc Prospective,et al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies , 2002 .
[59] Ali G. Gharavi,et al. Molecular Mechanisms of Human Hypertension , 2001, Cell.
[60] Luigi Ferrucci,et al. Subsystems Contributing to the Decline in Ability to Walk: Bridging the Gap Between Epidemiology and Geriatric Practice in the InCHIANTI Study , 2000, Journal of the American Geriatrics Society.
[61] D. Zeeuw,et al. Urinary albumin excretion is associated with renal functional abnormalities in a nondiabetic population. , 2000, Journal of the American Society of Nephrology : JASN.
[62] K. Roeder,et al. Genomic Control for Association Studies , 1999, Biometrics.
[63] N. Day,et al. EPIC-Norfolk: study design and characteristics of the cohort. European Prospective Investigation of Cancer. , 1999, British journal of cancer.
[64] L. Daviet,et al. Cloning and Characterization of ATRAP, a Novel Protein That Interacts with the Angiotensin II Type 1 Receptor* , 1999, The Journal of Biological Chemistry.
[65] J. Brockmöller,et al. Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine. , 1999, British journal of clinical pharmacology.
[66] G Dunn,et al. Rationale and design. PRiSM Psychosis Study I. , 1998, The British journal of psychiatry : the journal of mental science.
[67] V. Salomaa,et al. Trends in blood pressure levels and control of hypertension in Finland from 1982 to 1997 , 1998, Journal of hypertension.
[68] R N Bergman,et al. Mapping Genes for NIDDM: Design of the Finland—United States Investigation of NIDDM Genetics (FUSION) Study , 1998, Diabetes Care.
[69] P. Galan,et al. Background and rationale behind the SU.VI.MAX Study, a prevention trial using nutritional doses of a combination of antioxidant vitamins and minerals to reduce cardiovascular diseases and cancers. SUpplementation en VItamines et Minéraux AntioXydants Study. , 1998, International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.
[70] T. Arinami,et al. Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia. , 1997, Journal of medical genetics.
[71] W. Miller,et al. The genetic and functional basis of isolated 17,20–lyase deficiency , 1997, Nature Genetics.
[72] R. Lifton,et al. Genetic heterogeneity of Barter's syndrome revealed by mutations in the K+ channel, ROMK , 1996, Nature Genetics.
[73] K. Eriksson,et al. Cardiovascular risk groups and mortality in an urban Swedish male population: the Malmö Preventive Project , 1996, Journal of internal medicine.
[74] R. Lifton,et al. Gitelman's variant of Barter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na–Cl cotransporter , 1996, Nature Genetics.
[75] P. Frosst,et al. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. , 1996, American journal of human genetics.
[76] O. Smithies,et al. Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension , 1995, Science.
[77] P. Elliott,et al. Urinary Electrolyte Excretion in 24 Hours and Blood Pressure in the INTERSALT Study I. Estimates of Reliability , 1994 .
[78] G. Berglund,et al. Design and feasibility , 1993 .
[79] Nature Genetics , 1991, Nature.
[80] M Marmot,et al. INTERSALT Study Findings Public Health and Medical Care Implications , 1989, Hypertension.
[81] R. Sainsbury,et al. Variability in the elimination of mianserin in elderly patients. , 1989, British journal of clinical pharmacology.
[82] David Arenberg,et al. Normal Human Aging: The Baltimore Longitudinal Study on Aging , 1984 .
[83] Langford Hg. The hypertension detection and follow-up program. , 1984 .
[84] W. Kannel,et al. Blood pressure aggregation in families. , 1979, American journal of epidemiology.
[85] Variability of blood pressure and the results of screening in the hypertension detection and follow-up program. , 1978, Journal of chronic diseases.