Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage

[1]  G. Nixon,et al.  Sphingosylphosphorylcholine is a Proinflammatory Mediator in Cerebral Arteries , 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[2]  T. Takato,et al.  Trehalose inhibits oral dryness by protecting the cell membrane. , 2010, International Journal of Oral & Maxillofacial Surgery.

[3]  S. Homer-Vanniasinkam,et al.  A review of delayed ischemic neurologic deficit following aneurysmal subarachnoid hemorrhage: historical overview, current treatment, and pathophysiology. , 2010, World neurosurgery.

[4]  I. Roy,et al.  Effect of trehalose on protein structure , 2008, Protein science : a publication of the Protein Society.

[5]  S. Mayer,et al.  Clazosentan to Overcome Neurological Ischemia and Infarction Occurring After Subarachnoid Hemorrhage (CONSCIOUS-1): Randomized, Double-Blind, Placebo-Controlled Phase 2 Dose-Finding Trial , 2008, Stroke.

[6]  A. Rosa,et al.  Protective effect of hydroxytyrosol and its metabolite homovanillic alcohol on H(2)O(2) induced lipid peroxidation in renal tubular epithelial cells. , 2008, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[7]  A. Bitto,et al.  Trehalose: a biophysics approach to modulate the inflammatory response during endotoxic shock. , 2008, European journal of pharmacology.

[8]  John H. Zhang,et al.  The effect of ecdysterone on cerebral vasospasm following experimental subarachnoid hemorrhage in vitro and in vivo , 2008, Neurological research.

[9]  C. Trandafir,et al.  Pharmacological nature of nicotine-induced contraction in the rat basilar artery: involvement of arachidonic acid metabolites. , 2007, European journal of pharmacology.

[10]  J. Mocco,et al.  Advances in vasospasm treatment and prevention , 2007, Journal of the Neurological Sciences.

[11]  Ji-Xin Shi,et al.  Potential Contribution of Nuclear Factor-κB to Cerebral Vasospasm after Experimental Subarachnoid Hemorrhage in Rabbits , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[12]  R. Macdonald,et al.  Cerebral vasospasm after subarachnoid hemorrhage: the emerging revolution , 2007, Nature Clinical Practice Neurology.

[13]  P. Chan,et al.  Reduction in Oxidative Stress by Superoxide Dismutase Overexpression Attenuates Acute Brain Injury after Subarachnoid Hemorrhage via Activation of Akt/Glycogen Synthase Kinase-3β Survival Signaling , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[14]  A. Cruickshank,et al.  Subarachnoid haemorrhage , 2007, The Lancet.

[15]  A. Bitto,et al.  THE DISACCHARIDE TREHALOSE INHIBITS PROINFLAMMATORY PHENOTYPE ACTIVATION IN MACROPHAGES AND PREVENTS MORTALITY IN EXPERIMENTAL SEPTIC SHOCK , 2007, Shock.

[16]  A. Panek,et al.  Trehalose protects Saccharomyces cerevisiae from lipid peroxidation during oxidative stress. , 2006, Biochimica et biophysica acta.

[17]  O. Inanami,et al.  Synthesis and characterization of a practically better DEPMPO-type spin trap, 5-(2,2-dimethyl-1,3-propoxy cyclophosphoryl)-5-methyl-1-pyrroline N-oxide (CYPMPO) , 2006, Free radical research.

[18]  Takao Shimizu,et al.  Identification of Novel Cytosolic Phospholipase A2s, Murine cPLA2δ, ϵ, and ζ, Which Form a Gene Cluster with cPLA2β* , 2005, Journal of Biological Chemistry.

[19]  S. Hasegawa,et al.  Effective application of ET-Kyoto solution for clinical lung transplantation. , 2004, Transplantation proceedings.

[20]  Takao Shimizu,et al.  Regulatory mechanism and physiological role of cytosolic phospholipase A2. , 2004, Biological & pharmaceutical bulletin.

[21]  T. Hori,et al.  Role of p38 Mitogen-Activated Protein Kinase on Cerebral Vasospasm After Subarachnoid Hemorrhage , 2004, Stroke.

[22]  Y. Inoue,et al.  NMR and quantum chemical study on the OH...pi and CH...O interactions between trehalose and unsaturated fatty acids: implication for the mechanism of antioxidant function of trehalose. , 2003, Journal of the American Chemical Society.

[23]  R. J. Dumont,et al.  Cerebral Vasospasm after Subarachnoid Hemorrhage: Putative Role of Inflammation , 2003, Neurosurgery.

[24]  J. Bonventre,et al.  Cross-talk between Cytosolic Phospholipase A2α (cPLA2α) and Secretory Phospholipase A2 (sPLA2) in Hydrogen Peroxide-induced Arachidonic Acid Release in Murine Mesangial Cells , 2003, Journal of Biological Chemistry.

[25]  A. Elbein,et al.  New insights on trehalose: a multifunctional molecule. , 2003, Glycobiology.

[26]  T. Matsuo,et al.  Trehalose eye drops in the treatment of dry eye syndrome. , 2002, Ophthalmology.

[27]  S. Howng,et al.  Attenuation of hemolysate-induced cerebrovascular endothelial cell injury and of production of endothelin-1 and big endothelin-1 by an endothelin-converting enzyme inhibitor. , 2002, Surgical neurology.

[28]  R. Sercombe,et al.  Cerebrovascular inflammation following subarachnoid hemorrhage. , 2002, Japanese journal of pharmacology.

[29]  J. Avruch,et al.  Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. , 2001, Physiological reviews.

[30]  R. Sercombe,et al.  Overexpression of Cyclooxygenase-2 in Rabbit Basilar Artery Endothelial Cells after Subarachnoid Hemorrhage , 2001, Neurosurgery.

[31]  S. Akiba,et al.  Involvement of Group VI Ca2+-independent Phospholipase A2 in Protein Kinase C-dependent Arachidonic Acid Liberation in Zymosan-stimulated Macrophage-like P388D1 Cells* , 1999, The Journal of Biological Chemistry.

[32]  Ralph,et al.  Inducible nitric oxide synthase: a possible key factor in the pathogenesis of chronic vasospasm after experimental subarachnoid hemorrhage. , 1999, Journal of neurosurgery.

[33]  T. Asano,et al.  Antioxidant Therapy Against Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage , 1999, Cellular and Molecular Neurobiology.

[34]  R J Tamargo,et al.  Inhibition of experimental vasospasm with anti-intercellular adhesion molecule-1 monoclonal antibody in rats. , 1997, Stroke.

[35]  R. Macdonald,et al.  A review of hemoglobin and the pathogenesis of cerebral vasospasm. , 1991, Stroke.

[36]  M. Mayberg,et al.  A rat femoral artery model for vasospasm. , 1990, Neurosurgery.

[37]  R. Rodriguez y Baena,et al.  Arachidonate metabolites and vasospasm after subarachnoid haemorrhage. , 1986, Neurological research.

[38]  田谷 かほる Trehalose inhibits inflammatory cytokine production by protecting IκB-α reduction in mouse peritoneal macrophages , 2009 .

[39]  John H. Zhang,et al.  Oxidative stress in subarachnoid haemorrhage: significance in acute brain injury and vasospasm. , 2008, Acta neurochirurgica. Supplement.

[40]  J. Bonventre,et al.  Cross-talk between cytosolic phospholipase A2 alpha (cPLA2 alpha) and secretory phospholipase A2 (sPLA2) in hydrogen peroxide-induced arachidonic acid release in murine mesangial cells: sPLA2 regulates cPLA2 alpha activity that is responsible for arachidonic acid release. , 2003, The Journal of biological chemistry.

[41]  P. Tak,et al.  NF-κB: a key role in inflammatory diseases , 2001 .

[42]  R. Tamargo,et al.  Inhibition of experimental vasospasm in rats with the periadventitial administration of ibuprofen using controlled-release polymers. , 1999, Stroke.

[43]  J. Carpenter,et al.  The role of vitrification in anhydrobiosis. , 1998, Annual review of physiology.