Computationally Efficient Models of Flow-through Affinity-ba sed Assays

We present a new paradigm for modeling, simulation, and optimal design of biosensors, based on an innovative, computationally efficient formulation. Here we illustrate the approach on the design of flow-through affinity-based (a.k.a. lateral flow) bioassays. We briefly discuss the mathematical and computational models and present an example of parameter optimization and performance tradeoffs.