New Doppler-based imaging method in echocardiography with applications in blood/tissue segmentation

A parametric model for the ultrasound signals from blood and tissue is developed and a new imaging method, knowledge-based imaging, is defined. This method utilizes the likelihood ratio function to classify blood and tissue signals. The method separates blood and tissue signals by the difference in movement patterns in addition to the difference in powers. The prior information about the levels of expected system white noise and clutter noise are utilized to enhance the image quality. The implementation of knowledge-based imaging is outlined, and some knowledge-based images with different parameter settings are visually compared with a second-harmonic image, a fundamental image and a bandwidth image. In order to understand the parameter estimation process a computer simulation is introduced to outline the differences between the imaging methods. The apparent error rates are calculated in any reasonable tissue to blood signal ratio, tissue to white noise ratio and clutter to white noise ratio. A discussion of further development of knowledge-based imaging is also described in this paper.

[1]  V. Algazi,et al.  A new wideband spread target maximum likelihood estimator for blood velocity estimation. I. Theory , 1991, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[2]  Bjørn Olstad,et al.  New echocardiographic imaging method based on the bandwidth of the ultrasound Doppler signal with applications in blood/tissue segmentation in the left ventricle , 2008, Comput. Methods Programs Biomed..

[3]  K. Caidahl,et al.  New concept in echocardiography: harmonic imaging of tissue without use of contrast agent , 1998, The Lancet.

[4]  E. L. Dove,et al.  A Method for Automatic Edge Detection and Volume Computation of the Left Ventricle from Ultrafast Computed Tomographic Images , 1994, Investigative radiology.

[5]  T. Ebbers,et al.  Particle trace visualization of intracardiac flow using time‐resolved 3D phase contrast MRI , 1999, Magnetic resonance in medicine.

[6]  Michael G. Strintzis,et al.  Tracking the left ventricle in echocardiographic images by learning heart dynamics , 1999, IEEE Transactions on Medical Imaging.

[7]  Bjorn A. J. Angelsen,et al.  A Theoretical Study of the Scattering of Ultrasound from Blood , 1980, IEEE Transactions on Biomedical Engineering.

[8]  Andrew Blake,et al.  Evaluating a robust contour tracker on echocardiographic sequences , 1999, Medical Image Anal..

[9]  U. Frisch Turbulence: The Legacy of A. N. Kolmogorov , 1996 .

[10]  Andrea Giachetti On-line analysis of echocardiographic image sequences , 1998, Medical Image Anal..

[11]  Thomas F. Coleman,et al.  An Interior Trust Region Approach for Nonlinear Minimization Subject to Bounds , 1993, SIAM J. Optim..

[12]  James S. Duncan,et al.  Shape-based tracking of left ventricular wall motion , 1997, IEEE Transactions on Medical Imaging.

[13]  Bjørn Olstad,et al.  Bandwidth of the Ultrasound Doppler Signal with Applications in Blood/Tissue Segmentation in the Left Ventricle , 2007, MIMI.

[14]  K. Kristoffersen,et al.  Autocorrelation techniques in color flow imaging: signal model and statistical properties of the autocorrelation estimates , 1994, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[15]  Le Thi Hoai An,et al.  A Branch and Bound Method via d.c. Optimization Algorithms and Ellipsoidal Technique for Box Constrained Nonconvex Quadratic Problems , 1998, J. Glob. Optim..

[16]  A. D. Gosman,et al.  Computational Flow Modeling of the Left Ventricle Based on In Vivo MRI Data: Initial Experience , 2001, Annals of Biomedical Engineering.

[17]  S. Satomura,et al.  Ultrasonic Doppler Method for the Inspection of Cardiac Functions , 1957 .

[18]  Thomas L. Marzetta,et al.  Detection, Estimation, and Modulation Theory , 1976 .

[19]  Timothy F. Cootes,et al.  Active Shape Models-Their Training and Application , 1995, Comput. Vis. Image Underst..

[20]  R.W.B. Stephens,et al.  IEEE ultrasonics symposium , 1972 .

[21]  Milan Sonka,et al.  Segmentation of intravascular ultrasound images: a knowledge-based approach , 1995, IEEE Trans. Medical Imaging.

[22]  Harry L. Van Trees,et al.  Detection, Estimation, and Modulation Theory: Radar-Sonar Signal Processing and Gaussian Signals in Noise , 1992 .

[23]  Colin Deane,et al.  Estimation of blood velocities using ultrasound: a signal processing approach:Jorgen Arendt Jensen, Cambridge University Press, ISBN: 0 521 46484 6, 317pp, £45.00 ($69.95) , 1997 .

[24]  James D. Thomas,et al.  Segmentation and tracking in echocardiographic sequences: active contours guided by optical flow estimates , 1998, IEEE Transactions on Medical Imaging.

[25]  Demetri Terzopoulos,et al.  Snakes: Active contour models , 2004, International Journal of Computer Vision.

[26]  H. Torp,et al.  Detecting small blood vessels in color flow imaging: a statistical approach , 1997, 1997 IEEE Ultrasonics Symposium Proceedings. An International Symposium (Cat. No.97CH36118).

[27]  K. Kristoffersen Optimal Receiver Filtering in Pulsed Doppler Ultrasound Blood Velocity Measurements , 1986, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[28]  M. Cerqueira,et al.  Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. , 2002, Circulation.

[29]  Charles E. Heckler,et al.  Applied Multivariate Statistical Analysis , 2005, Technometrics.

[30]  Sigmund Frigstad,et al.  Accurate and reproducible measurement of left ventricular volume and ejection fraction by contrast echocardiography: a comparison with magnetic resonance imaging. , 2004, Journal of the American College of Cardiology.

[31]  K B Chandran,et al.  Velocity and turbulence measurements past mitral valve prostheses in a model left ventricle. , 1991, Journal of biomechanics.

[32]  O. Bonnefous,et al.  Time Domain Formulation of Pulse-Doppler Ultrasound and Blood Velocity Estimation by Cross Correlation , 1986, Ultrasonic imaging.

[33]  Haim J. Wolfson,et al.  Articulated object recognition, or: how to generalize the generalized Hough transform , 1991, Proceedings. 1991 IEEE Computer Society Conference on Computer Vision and Pattern Recognition.

[34]  Alan L. Yuille,et al.  Feature extraction from faces using deformable templates , 2004, International Journal of Computer Vision.

[35]  Milan Sonka,et al.  Active Appearance - Motion Models for fully automated endocardial contour detection in time sequences of echocardiograms , 2001, CARS.

[36]  Robert C. Waag,et al.  Ultrasound Imaging: Waves, Signals, and Signal Processing , 2007 .

[37]  G E Trahey,et al.  A real time system for quantifying and displaying two-dimensional velocities using ultrasound. , 1993, Ultrasound in medicine & biology.

[38]  J. Wild The use of ultrasonic pulses for the measurement of biologic tissues and the detection of tissue density changes. , 1950, Surgery.

[39]  Einar Heiberg,et al.  Transit of blood flow through the human left ventricle mapped by cardiovascular magnetic resonance. , 2007, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[40]  Lewis F. Richardson,et al.  Weather Prediction by Numerical Process , 1922 .

[41]  R. Lang,et al.  Use of harmonic imaging without echocardiographic contrast to improve two-dimensional image quality. , 1998, The American journal of cardiology.

[42]  R.S. Lewandowski,et al.  Improved in vivo abdominal image quality using real-time estimation and correction of wavefront arrival time errors , 2000, 2000 IEEE Ultrasonics Symposium. Proceedings. An International Symposium (Cat. No.00CH37121).

[43]  C. H. Hertz,et al.  The Use of Ultrasonic Reflectoscope for the Continuous Recording of the Movements of Heart Walls. , 2004, Clinical physiology and functional imaging.

[44]  A. Cenedese,et al.  A laboratory investigation of the flow in the left ventricle of a human heart with prosthetic, tilting-disk valves , 2005 .

[45]  H. Torp,et al.  Ultrasound doppler measurements of low velocity blood flow: limitations due to clutter signals from vibrating muscles , 1997, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[46]  J H Reiber,et al.  Evaluation of a semiautomatic contour detection approach in sequences of short-axis two-dimensional echocardiographic images. , 1995, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[47]  H. Torp Clutter rejection filters in color flow imaging: a theoretical approach , 1997, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[48]  R. Jirik,et al.  High-resolution ultrasonic imaging using two-dimensional homomorphic filtering , 2006, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[49]  Bjørn Olstad,et al.  New Doppler-Based Imaging Method in Echocardiography with Applications in Blood/Tissue Segmentation , 2007, MIMI.

[50]  Young Bok Ahn,et al.  Estimation of mean frequency and variance of ultrasonic Doppler signal by using second-order autoregressive model , 1991, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[51]  D. H. Howry,et al.  Ultrasonic visualization of soft tissue structures of the body. , 1952, The Journal of laboratory and clinical medicine.