Evaluation of Clinical, Serum Biochemical and Oxidant-antioxidant Profiles in Dairy Cows with Left Abomasal Displacement

Objective: This study aimed to evaluate the clinical and laboratory metabolic alterations in left displaced abomasum cattle with particular emphasis on the oxidative effects. Methodology: Cows with left displaced abomasum were confirmed on the basis of clinical symptoms. Blood samples were collected from 12 diseased cows during 4-6 weeks after parturition and were assayed for the selected biochemical parameters. Another 10 healthy cows were selected from similar environmental conditions and served as control. Results: The results showed that serum values of glucose, urea, creatinine, aspartate aminotransferase and amylase were significantly increased in the left displaced abomasum cows whereas, a significant decrease was found in serum concentrations of total protein, albumin, cholesterol, calcium, phosphorus, sodium, potassium and chloride. Metabolic alkalosis was evidenced by the significant elevation in blood bicarbonate concentrations plus pH. Oxidant-antioxidant study revealed a significant increase in the levels of hydrogen peroxide, nitric oxide and malondialdehyde in the diseased group while, serum enzymatic activities of catalase and glutathione reductase demonstrated a significant decrease. Conclusion: It was concluded that oxidative stress appeared to contribute in the pathogenesis of abomasal displacement in cattle and thus using of anti-oxidant therapies is recommended both to prevent and treat the disease.