Renal denervation with ultrasound therapy (paradise device) is an effective therapy for systemic hypertension.

Hypertension is the most important risk factor for cardiovascular events associated morbidity and mortality, affecting more than one billion people worldwide (1). Although anti-hypertensive drug therapy is very effective in reducing the risk of cardiovascular disease and death, approximately 10% of patients suffer from resistant hypertension despite at least three maximally tolerated doses of anti-hypertensive drugs including a diuretic (2).