Microbial metabolism of thiopurines: A method to measure thioguanine nucleotides.

[1]  P. Savelkoul,et al.  Fecal Microbial Composition of Ulcerative Colitis and Crohn’s Disease Patients in Remission and Subsequent Exacerbation , 2014, PloS one.

[2]  H. Li,et al.  Cometabolism of Microbes and Host: Implications for Drug Metabolism and Drug‐Induced Toxicity , 2013, Clinical pharmacology and therapeutics.

[3]  N. von Ahsen,et al.  Improved Method for Therapeutic Drug Monitoring of 6-Thioguanine Nucleotides and 6-Methylmercaptopurine in Whole-Blood by LC/MSMS Using Isotope-Labeled Internal Standards , 2013, Therapeutic drug monitoring.

[4]  S. Vikingsson,et al.  Monitoring of thiopurine metabolites - a high-performance liquid chromatography method for clinical use. , 2013, Journal of pharmaceutical and biomedical analysis.

[5]  S. Hansen,et al.  Determination of leukocyte DNA 6-thioguanine nucleotide levels by high-performance liquid chromatography with fluorescence detection. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[6]  S. Shin,et al.  Thiopurine Drugs Azathioprine and 6-Mercaptopurine Inhibit Mycobacterium paratuberculosis Growth In Vitro , 2007, Antimicrobial Agents and Chemotherapy.

[7]  R. D. De Abreu,et al.  Monitoring of inosine monophosphate dehydrogenase activity in mononuclear cells of children with acute lymphoblastic leukemia: Enzymological and clinical aspects , 2006, Pediatric blood & cancer.

[8]  K. Adeli,et al.  Improved HPLC methodology for monitoring thiopurine metabolites in patients on thiopurine therapy. , 2004, Clinical biochemistry.

[9]  M. Neurath,et al.  CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. , 2003, The Journal of clinical investigation.

[10]  M. Relling,et al.  HPLC determination of thiopurine nucleosides and nucleotides in vivo in lymphoblasts following mercaptopurine therapy. , 2002, Clinical chemistry.

[11]  R. D. De Abreu,et al.  Determination of extracellular and intracellular thiopurines and methylthiopurines by high-performance liquid chromatography. , 1995, Journal of chromatography. B, Biomedical applications.

[12]  L. Lennard,et al.  Assay of 6-thioinosinic acid and 6-thioguanine nucleotides, active metabolites of 6-mercaptopurine, in human red blood cells. , 1987, Journal of chromatography.

[13]  C. Caskey,et al.  HPRT: gene structure, expression, and mutation. , 1985, Annual review of genetics.

[14]  A. Stempel,et al.  Antimetabolites produced by microorganisms. 3. 2-aminopurine-6-thiol (thioguanine). , 1971, The Journal of antibiotics.

[15]  H. G. Mandel,et al.  The actions of thioguanine in Bacillus cereus. , 1965, Biochemical pharmacology.