Pharmacological Manipulation of Trk, p75NTR, and NGF Balance Restores Memory Deficit in Global Ischemia/Reperfusion Model in Rats

[1]  M. Soligo,et al.  The mature/pro nerve growth factor ratio is decreased in the brain of diabetic rats: Analysis by ELISA methods , 2015, Brain Research.

[2]  T. L. Briones,et al.  Neuroprotective effects of enriched environment housing after transient global cerebral ischaemia are associated with the upregulation of insulin‐like growth factor‐1 signalling , 2015, Neuropathology and applied neurobiology.

[3]  Mark D. Huffman,et al.  AHA Statistical Update Heart Disease and Stroke Statistics — 2012 Update A Report From the American Heart Association WRITING GROUP MEMBERS , 2010 .

[4]  Renshi Xu,et al.  The possible mechanism of Parkinson’s disease progressive damage and the preventive effect of GM1 in the rat model induced by 6-hydroxydopamine , 2014, Brain Research.

[5]  Luyong Zhang,et al.  Nafamostat mesilate attenuates neuronal damage in a rat model of transient focal cerebral ischemia through thrombin inhibition , 2014, Scientific Reports.

[6]  Stephanie A. Carmack,et al.  Methylphenidate enhances acquisition and retention of spatial memory , 2014, Neuroscience Letters.

[7]  C. Iadecola,et al.  MiR-592 Regulates the Induction and Cell Death-Promoting Activity of p75NTR in Neuronal Ischemic Injury , 2014, The Journal of Neuroscience.

[8]  Maha M Coucha,et al.  Protein nitration impairs the myogenic tone of rat middle cerebral arteries in both ischemic and nonischemic hemispheres after ischemic stroke. , 2013, American journal of physiology. Heart and circulatory physiology.

[9]  N. Berretta,et al.  ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice , 2013, Cell Death and Differentiation.

[10]  T. Sanderson,et al.  Molecular Mechanisms of Ischemia–Reperfusion Injury in Brain: Pivotal Role of the Mitochondrial Membrane Potential in Reactive Oxygen Species Generation , 2013, Molecular Neurobiology.

[11]  L. Manni,et al.  Nerve growth factor: from the early discoveries to the potential clinical use , 2012, Journal of Translational Medicine.

[12]  M. Vinciguerra,et al.  Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats , 2012, British journal of pharmacology.

[13]  K. Fouad,et al.  Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice , 2012, Proceedings of the National Academy of Sciences.

[14]  W. Friedman,et al.  Matrix Metalloproteinase-7 Regulates Cleavage of Pro-Nerve Growth Factor and Is Neuroprotective following Kainic Acid-Induced Seizures , 2012, The Journal of Neuroscience.

[15]  I. Arisi,et al.  A dual mechanism linking NGF/proNGF imbalance and early inflammation to Alzheimer's disease neurodegeneration in the AD11 anti-NGF mouse model. , 2011, CNS & neurological disorders drug targets.

[16]  N. Koibuchi,et al.  Ligand‐induced downregulation of TrkA is partly regulated through ubiquitination by Cbl , 2011, FEBS letters.

[17]  Sung-Chun Tang,et al.  Pathophysiology, treatment, and animal and cellular models of human ischemic stroke , 2011, Molecular Neurodegeneration.

[18]  M. Abdelsaid,et al.  Epicatechin blocks pro-nerve growth factor (proNGF)-mediated retinal neurodegeneration via inhibition of p75 neurotrophin receptor proNGF expression in a rat model of diabetes , 2011, Diabetologia.

[19]  B. Hempstead,et al.  ProNGF Induces PTEN via p75NTR to Suppress Trk-Mediated Survival Signaling in Brain Neurons , 2010, The Journal of Neuroscience.

[20]  R. Neumar,et al.  Part 9: post-cardiac arrest care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. , 2010, Circulation.

[21]  S. Biswal,et al.  The Flavanol (−)-Epicatechin Prevents Stroke Damage through the Nrf2/HO1 Pathway , 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[22]  K. Teng,et al.  Understanding proneurotrophin actions: Recent advances and challenges , 2010, Developmental neurobiology.

[23]  Rolando X. Aviles‐Reyes,et al.  p75NTR Expression is induced in isolated neurons of the penumbra after ischemia by cortical devascularization , 2009, Journal of neuroscience research.

[24]  D. Wade,et al.  Cognitive impairments in survivors of out-of-hospital cardiac arrest: a systematic review. , 2009, Resuscitation.

[25]  G. Keilhoff,et al.  Bmc Molecular Biology Selection of Reference Genes for Quantitative Real-time Pcr in a Rat Asphyxial Cardiac Arrest Model , 2022 .

[26]  H. Bramlett,et al.  Modulation of the cAMP signaling pathway after traumatic brain injury , 2007, Experimental Neurology.

[27]  Gene W. Yeo,et al.  Plant-Derived Flavanol (−)Epicatechin Enhances Angiogenesis and Retention of Spatial Memory in Mice , 2007, The Journal of Neuroscience.

[28]  L. Reichardt,et al.  Neurotrophin-regulated signalling pathways , 2006, Philosophical Transactions of the Royal Society B: Biological Sciences.

[29]  P. Barker,et al.  p75 neurotrophin receptor reduces ligand‐induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation , 2005, EMBO reports.

[30]  I. Mocchetti Exogenous gangliosides, neuronal plasticity and repair, and the neurotrophins , 2005, Cellular and Molecular Life Sciences CMLS.

[31]  Petti T. Pang,et al.  The yin and yang of neurotrophin action , 2005, Nature Reviews Neuroscience.

[32]  Larry R Squire,et al.  Spatial memory, recognition memory, and the hippocampus. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[33]  M. Meyer,et al.  Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[34]  Jing Liu,et al.  JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD. , 2004, Molecular cell.

[35]  D. Chung,et al.  Down-regulation of the Tumor Suppressor PTEN by the Tumor Necrosis Factor-α/Nuclear Factor-κB (NF-κB)-inducing Kinase/NF-κB Pathway Is Linked to a Default IκB-α Autoregulatory Loop* , 2004, Journal of Biological Chemistry.

[36]  P. Gordon-Weeks,et al.  NGF activates the phosphorylation of MAP1B by GSK3β through the TrkA receptor and not the p75NTR receptor , 2003, Journal of neurochemistry.

[37]  H. Baba,et al.  Different Expression Patterns of Bcl-2, Bcl-xl, and Bax Proteins After Sublethal Forebrain Ischemia in C57Black/Crj6 Mouse Striatum , 2003, Stroke.

[38]  M. Chao,et al.  Neurotrophins and their receptors: A convergence point for many signalling pathways , 2003, Nature Reviews Neuroscience.

[39]  A. Bachis,et al.  Gangliosides Activate Trk Receptors by Inducing the Release of Neurotrophins* , 2002, The Journal of Biological Chemistry.

[40]  J. Kim,et al.  ProNGF Induces p75-Mediated Death of Oligodendrocytes following Spinal Cord Injury , 2002, Neuron.

[41]  G. Hankey,et al.  Gangliosides for Acute Ischemic Stroke , 2002, Stroke.

[42]  Hirofumi Nakatomi,et al.  Regeneration of Hippocampal Pyramidal Neurons after Ischemic Brain Injury by Recruitment of Endogenous Neural Progenitors , 2002, Cell.

[43]  Philippe P Roux,et al.  Neurotrophin signaling through the p75 neurotrophin receptor , 2002, Progress in Neurobiology.

[44]  J. Kim,et al.  Activation of Rac GTPase by p75 Is Necessary for c-jun N-Terminal Kinase-Mediated Apoptosis , 2002, The Journal of Neuroscience.

[45]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[46]  Barbara L. Hempstead,et al.  Regulation of Cell Survival by Secreted Proneurotrophins , 2001, Science.

[47]  Francesca Zazzeroni,et al.  Induction of gadd45β by NF-κB downregulates pro-apoptotic JNK signalling , 2001, Nature.

[48]  Y. Yarden,et al.  Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases , 2001, FEBS letters.

[49]  F. Gage,et al.  Regenerating the damaged central nervous system , 2000, Nature.

[50]  A. Brambrink,et al.  Tolerance-Inducing Dose of 3-Nitropropionic Acid Modulates bcl-2 and bax Balance in the Rat Brain: A Potential Mechanism of Chemical Preconditioning , 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[51]  T. Taoka,et al.  Hippocampal Damage in the Human Brain after Cardiac Arrest , 2000, Cerebrovascular Diseases.

[52]  A. Heimann,et al.  Laser-Doppler scanning of local cerebral blood flow and reserve capacity and testing of motor and memory functions in a chronic 2-vessel occlusion model in rats. , 1998, Stroke.

[53]  Y. Itoyama,et al.  Expression of nerve growth factor and trkA after transient focal cerebral ischemia in rats. , 1998, Stroke.

[54]  O. Lindvall,et al.  Focal cerebral ischemia in rats induces expression of p75 neurotrophin receptor in resistant striatal cholinergic neurons , 1998, Neuroscience.

[55]  Milton Alter GM1 Ganglioside for Acute Ischemic Stroke: Trial Design Issues , 1998, Annals of the New York Academy of Sciences.

[56]  M. Chao,et al.  Competitive Signaling Between TrkA and p75 Nerve Growth Factor Receptors Determines Cell Survival , 1998, The Journal of Neuroscience.

[57]  N. Neff,et al.  GM1 Ganglioside: In Vivo and In Vitro Trophic Actions on Central Neurotransmitter Systems , 1998, Journal of neurochemistry.

[58]  W. Banks,et al.  Permeability of the blood–brain barrier to neurotrophins , 1998, Brain Research.

[59]  M. M. Glasier,et al.  Effects of a Single Intraseptal Injection of NGF on Spatial Learning in the Water Maze , 1997, Physiology & Behavior.

[60]  T. Fong,et al.  GM1 ganglioside improves spatial learning and memory of aged rats , 1997, Behavioural Brain Research.

[61]  J. Sahel,et al.  P 351 Monosialoganglioside GM1 reduces ischemia-reperfusion induced injury in the rat retina , 1995, Vision Research.

[62]  A. Davies The Bcl-2 family of proteins, and the regulation of neuronal survival , 1995, Trends in Neurosciences.

[63]  I. Mocchetti,et al.  GM1 Ganglioside Activates the High‐Affinity Nerve Growth Factor Receptor trkA , 1995, Journal of neurochemistry.

[64]  G. Lenzi,et al.  Early Treatment of Stroke With Monosialoganglioside GM‐1: Efficacy and Safety Results of the Early Stroke Trial , 1994, Stroke.

[65]  H. Manev,et al.  GM1 Reduces Infarct Volume after Focal Cerebral Ischemia , 1994, Experimental Neurology.

[66]  R. Jaenisch,et al.  p75-Deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins , 1993, Neuron.

[67]  C. Waters,et al.  Endocytosis of growth factor receptors , 1993, BioEssays : news and reviews in molecular, cellular and developmental biology.

[68]  J. Krieglstein,et al.  Prevention of ischemia-induced cerebral hypothermia by controlling the environmental temperature. , 1992, Journal of pharmacological and toxicological methods.

[69]  S. Skaper,et al.  Hypoxic-ischemic damage and the neuroprotective effects of GM1 ganglioside. , 1990, Stroke.

[70]  C. Hopkins,et al.  Movement of internalized ligand–receptor complexes along a continuous endosomal reticulum , 1990, Nature.

[71]  ISSUE HIGHLIGHTS. , 2015, Genetics.

[72]  高橋 有我 Ligand-induced downregulation of TrkA is partly regulated through ubiquitination by Cbl , 2011 .

[73]  D. Chung,et al.  Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop. , 2004, The Journal of biological chemistry.

[74]  K. Teng,et al.  Neurotrophins and their receptors: signaling trios in complex biological systems , 2003, Cellular and Molecular Life Sciences CMLS.

[75]  J. Jones,et al.  Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling. , 2001, Nature.

[76]  R. Ledeen Ganglioside structures and distribution: are they localized at the nerve ending? , 1978, Journal of supramolecular structure.