Expression pattern of GATA‐3 in embryonic and fetal human skin suggests a role in epidermal and follicular morphogenesis

Background: The transcription factor GATA‐3 was recently identified as a master regulator in the specification of the inner root sheath. Additionally, it seems to play a role in skin barrier physiology. p63 binds and transactivates the GATA‐3 promoter. While the expression profile of GATA‐3 is delineated for the mouse, little is known about its expression in the adult human hair follicle and no studies are published about its distribution during human cutaneous embryogenesis.

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