Diffuse hypertrichosis during treatment with 5% topical minoxidil

Five women affected by androgenetic alopecia developed severe hypertrichosis of the face and limbs after 2‐3 months of treatment with 5% topical minoxidil. Minoxidil was discontinued and in all patients the hypertrichosis disappeared from the face and arms after 1‐3 months, and from legs after 4‐5 months. Systemic absorption of minoxidil, and a high sensitivity to minoxidil of the follicular apparatus in these areas, is hypothesized.

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