Intracellular processing of immunostimulatory CpG-siRNA: Toll-like receptor 9 facilitates siRNA dicing and endosomal escape.
暂无分享,去创建一个
M. Kortylewski | J. Rossi | Jiehua Zhou | P. Swiderski | C. Kowolik | Brian Armstrong | D. Moreira | A. Raubitschek | Sergey Nechaev | Chan Gao | Agnieszka Jozwiak
[1] Hua Yu,et al. TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo. , 2013, Blood.
[2] X. Chen,et al. Argonaute 2 Complexes Selectively Protect the Circulating MicroRNAs in Cell-Secreted Microvesicles , 2012, PloS one.
[3] Juliane Nguyen,et al. Nucleic acid delivery: the missing pieces of the puzzle? , 2012, Accounts of chemical research.
[4] R. Figlin,et al. S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites. , 2012, Cancer cell.
[5] H. Ploegh,et al. Granulin is a soluble cofactor for toll-like receptor 9 signaling. , 2011, Immunity.
[6] D. Zamboni,et al. A Method for Generation of Bone Marrow-Derived Macrophages from Cryopreserved Mouse Bone Marrow Cells , 2010, PloS one.
[7] Hua Yu,et al. Stat3-induced S1PR1 expression is critical for persistent Stat3 activation in tumors , 2010, Nature Medicine.
[8] O. Voinnet,et al. Control of RNA silencing and localization by endolysosomes. , 2010, Trends in cell biology.
[9] C. Kurts,et al. Cross-priming in health and disease , 2010, Nature Reviews Immunology.
[10] E. Gilboa,et al. Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay , 2010, Nature.
[11] D. Dykxhoorn,et al. Breaking down the barriers: siRNA delivery and endosome escape , 2010, Journal of Cell Science.
[12] Mark E. Davis,et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles , 2010, Nature.
[13] Hua Yu,et al. In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses , 2009, Nature Biotechnology.
[14] Anton P. McCaffrey,et al. Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors , 2009, Nature Biotechnology.
[15] B. Freedman,et al. Mechanism and Regulatory Function of CpG Signaling via Scavenger Receptor B1 in Primary B Cells* , 2009, The Journal of Biological Chemistry.
[16] John J. Rossi,et al. The promises and pitfalls of RNA-interference-based therapeutics , 2009, Nature.
[17] N. Escriou,et al. Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation. , 2008, Blood.
[18] Svetlana Shulga Morskaya,et al. 5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma , 2008, Nature Medicine.
[19] Sarah E. Ewald,et al. The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor , 2008, Nature.
[20] B. Pulendran,et al. Cross-presentation: avoiding trafficking chaos? , 2008, Nature Immunology.
[21] A. Judge,et al. 2'-O-methyl-modified RNAs act as TLR7 antagonists. , 2007, Molecular therapy : the journal of the American Society of Gene Therapy.
[22] A. Pasquinelli,et al. MicroRNA silencing through RISC recruitment of eIF6 , 2007, Nature.
[23] U. Landegren,et al. Direct observation of individual endogenous protein complexes in situ by proximity ligation , 2006, Nature Methods.
[24] R. Medzhitov,et al. On regulation of phagosome maturation and antigen presentation , 2006, Nature Immunology.
[25] D. Klinman,et al. CXCL16 Influences the Nature and Specificity of CpG-Induced Immune Activation12 , 2006, The Journal of Immunology.
[26] Yong Wang,et al. Cell type–specific delivery of siRNAs with aptamer-siRNA chimeras , 2006, Nature Biotechnology.
[27] Matthias John,et al. RNAi-mediated gene silencing in non-human primates , 2006, Nature.
[28] G. Rettig,et al. Progress Toward In Vivo Use of siRNAs-II , 2006, Molecular Therapy.
[29] Hua Yu,et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity , 2005, Nature Medicine.
[30] N. Zhong,et al. Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque , 2005, Nature Medicine.
[31] R. Shiekhattar,et al. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing , 2005, Nature.
[32] Mark E. Davis,et al. Functional polarity is introduced by Dicer processing of short substrate RNAs , 2005, Nucleic acids research.
[33] Judy Lieberman,et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors , 2005, Nature Biotechnology.
[34] Sangdun Choi,et al. Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy , 2005, Nature Biotechnology.
[35] M. Welte,et al. Bidirectional Transport along Microtubules , 2004, Current Biology.
[36] B. Monks,et al. TLR9 signals after translocating from the ER to CpG DNA in the lysosome , 2004, Nature Immunology.
[37] S. Akira,et al. A Subset of Toll-Like Receptor Ligands Induces Cross-presentation by Bone Marrow-Derived Dendritic Cells1 , 2003, The Journal of Immunology.
[38] B. Samuelsson,et al. Ribonuclease activity and RNA binding of recombinant human Dicer , 2002, The EMBO journal.
[39] Sergio Grinstein,et al. Phagosome maturation: aging gracefully. , 2002, The Biochemical journal.
[40] Etienne Gagnon,et al. Endoplasmic Reticulum-Mediated Phagocytosis Is a Mechanism of Entry into Macrophages , 2002, Cell.
[41] W. Filipowicz,et al. Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[42] M. Freeman,et al. The collagenous domains of macrophage scavenger receptors and complement component C1q mediate their similar, but not identical, binding specificities for polyanionic ligands. , 1993, The Journal of biological chemistry.
[43] F. Maxfield,et al. Endocytic recycling , 2004, Nature Reviews Molecular Cell Biology.