The Effects of Face Expertise Training on the Behavioral Performance and Brain Activity of Adults with High Functioning Autism Spectrum Disorders

The effect of expertise training with faces was studied in adults with ASD who showed initial impairment in face recognition. Participants were randomly assigned to a computerized training program involving either faces or houses. Pre- and post-testing included standardized and experimental measures of behavior and event-related brain potentials (ERPs), as well as interviews after training. After training, all participants met behavioral criteria for expertise with the specific stimuli on which they received training. Scores on standardized measures improved after training for both groups, but only the face training group showed an increased face inversion effect behaviorally and electrophysiological changes to faces in the P100 component. These findings suggest that individuals with ASD can gain expertise in face processing through training.

[1]  James W Tanaka,et al.  Using computerized games to teach face recognition skills to children with autism spectrum disorder: the Let's Face It! program. , 2010, Journal of child psychology and psychiatry, and allied disciplines.

[2]  G. Rhodes,et al.  Holistic Processing of Faces in Preschool Children and Adults , 2003, Psychological science.

[3]  U. Bellugi,et al.  Orientation and Affective Expression Effects on Face Recognition in Williams Syndrome and Autism , 2007, Journal of autism and developmental disorders.

[4]  D. Maurer,et al.  Configural Face Processing Develops more Slowly than Featural Face Processing , 2002, Perception.

[5]  M. Tarr,et al.  Expertise Training with Novel Objects Leads to Left-Lateralized Facelike Electrophysiological Responses , 2002, Psychological science.

[6]  Kristen L. Merkle,et al.  ERP responses differentiate inverted but not upright face processing in adults with ASD. , 2012, Social cognitive and affective neuroscience.

[7]  R. Joseph,et al.  Holistic and part-based face recognition in children with autism. , 2003, Journal of child psychology and psychiatry, and allied disciplines.

[8]  S. Baron-Cohen,et al.  Systemizing empathy: Teaching adults with Asperger syndrome or high-functioning autism to recognize complex emotions using interactive multimedia , 2006, Development and Psychopathology.

[9]  Anthony Bailey,et al.  Face and object processing in autism spectrum disorders , 2008, Autism research : official journal of the International Society for Autism Research.

[10]  Thomas Dierks,et al.  The development and evaluation of a computer-based program to test and to teach the recognition of facial affect , 2002, International journal of circumpolar health.

[11]  S. Schweinberger,et al.  Expertise and own-race bias in face processing: an event-related potential study , 2008, Neuroreport.

[12]  M. Arguin,et al.  Face perception in high-functioning autistic adults: evidence for superior processing of face parts, not for a configural face-processing deficit. , 2006, Neuropsychology.

[13]  A. Young,et al.  Configurational Information in Face Perception , 1987, Perception.

[14]  M. Tarr,et al.  Becoming a “Greeble” Expert: Exploring Mechanisms for Face Recognition , 1997, Vision Research.

[15]  M. Farah,et al.  Parts and Wholes in Face Recognition , 1993, The Quarterly journal of experimental psychology. A, Human experimental psychology.

[16]  Jocelyn Faubert,et al.  Recognition of faces and complex objects in younger and older adults , 2006, Memory & cognition.

[17]  B. Leventhal,et al.  The Autism Diagnostic Observation Schedule—Generic: A Standard Measure of Social and Communication Deficits Associated with the Spectrum of Autism , 2000, Journal of autism and developmental disorders.

[18]  A. Burton,et al.  Event-related brain potential evidence for a response of inferior temporal cortex to familiar face repetitions. , 2002, Brain research. Cognitive brain research.

[19]  Margot J. Taylor,et al.  Inversion and Contrast Polarity Reversal Affect both Encoding and Recognition Processes of Unfamiliar Faces: A Repetition Study Using ERPs , 2002, NeuroImage.

[20]  J. Tanaka,et al.  Features and their configuration in face recognition , 1997, Memory & cognition.

[21]  D. McIntosh,et al.  Rules versus Prototype Matching: Strategies of Perception of Emotional Facial Expressions in the Autism Spectrum , 2007, Journal of autism and developmental disorders.

[22]  Geraldine Dawson,et al.  Event-related brain potentials reveal anomalies in temporal processing of faces in autism spectrum disorder. , 2004, Journal of child psychology and psychiatry, and allied disciplines.

[23]  B. Gelder,et al.  Face processing in adolescents with autistic disorder: The inversion and composite effects , 2003, Brain and Cognition.

[24]  S. Baron-Cohen,et al.  Enhancing Emotion Recognition in Children with Autism Spectrum Conditions: An Intervention Using Animated Vehicles with Real Emotional Faces , 2010, Journal of autism and developmental disorders.

[25]  Kristen L. Merkle,et al.  Brief Report: Face Configuration Accuracy and Processing Speed Among Adults with High-Functioning Autism Spectrum Disorders , 2009, Journal of Autism and Developmental Disorders.

[26]  A. Klin,et al.  Absence of preferential looking to the eyes of approaching adults predicts level of social disability in 2-year-old toddlers with autism spectrum disorder. , 2008, Archives of general psychiatry.

[27]  S. Schweinberger,et al.  The age of the beholder: ERP evidence of an own-age bias in face memory , 2008, Neuropsychologia.

[28]  D. Maurer,et al.  Converging evidence of configural processing of faces in high-functioning adults with autism spectrum disorders , 2008 .

[29]  Dennis C. Hay,et al.  Configural information in face recognition , 1987 .

[30]  Valérie Goffaux,et al.  Characterizing the Spatio-temporal Dynamics of the Neural Events Occurring prior to and up to Overt Recognition of Famous Faces , 2010, Journal of Cognitive Neuroscience.

[31]  Margot J. Taylor,et al.  Effects of repetition learning on upright, inverted and contrast-reversed face processing using ERPs , 2004, NeuroImage.

[32]  James W. Tanaka,et al.  Activation of Preexisting and Acquired Face Representations: The N250 Event-related Potential as an Index of Face Familiarity , 2006, Journal of Cognitive Neuroscience.

[33]  Janet B W Williams,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[34]  Margot J. Taylor,et al.  The Faces of Development: A Review of Early Face Processing over Childhood , 2004, Journal of Cognitive Neuroscience.

[35]  M. Silver,et al.  Evaluation of a New Computer Intervention to Teach People with Autism or Asperger Syndrome to Recognize and Predict Emotions in Others , 2001, Autism : the international journal of research and practice.

[36]  David Wechsler,et al.  Wechsler Memory scale. , 2005 .

[37]  Geraldine Dawson,et al.  Abnormal functional connectivity in autism spectrum disorders during face processing. , 2008, Brain : a journal of neurology.

[38]  T. Ito,et al.  Race and gender on the brain: electrocortical measures of attention to the race and gender of multiply categorizable individuals. , 2003, Journal of personality and social psychology.

[39]  J. Hamm,et al.  Neurophysiological responses to face, facial regions and objects in adults with Asperger's syndrome: an ERP investigation. , 2007, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[40]  J. Tanaka,et al.  The NimStim set of facial expressions: Judgments from untrained research participants , 2009, Psychiatry Research.

[41]  Dc Washington Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. , 1994 .

[42]  J. Tanaka,et al.  Object categories and expertise: Is the basic level in the eye of the beholder? , 1991, Cognitive Psychology.

[43]  M. Tarr,et al.  Training ‘greeble’ experts: a framework for studying expert object recognition processes , 1998, Vision Research.

[44]  David L. Sheinberg,et al.  The role of category learning in the acquisition and retention of perceptual expertise: A behavioral and neurophysiological study , 2008, Brain Research.

[45]  N. Kanwisher,et al.  Can generic expertise explain special processing for faces? , 2007, Trends in Cognitive Sciences.

[46]  James W. Tanaka,et al.  What causes the face inversion effect , 1995 .

[47]  A. Freire,et al.  Face recognition in 4- to 7-year-olds: processing of configural, featural, and paraphernalia information. , 2001, Journal of experimental child psychology.

[48]  C. Tardif,et al.  Spatial Frequency and Face Processing in Children with Autism and Asperger Syndrome , 2004, Journal of autism and developmental disorders.

[49]  J. Cacioppo,et al.  Tracking the Timecourse of Social Perception: The Effects of Racial Cues on Event-Related Brain Potentials , 2004, Personality & social psychology bulletin.

[50]  Geraldine Dawson,et al.  Becoming a Face Expert: A Computerized Face-Training Program for High-Functioning Individuals With Autism Spectrum Disorders , 2007, Developmental neuropsychology.

[51]  Thomas Dierks,et al.  Facial affect recognition training in autism: can we animate the fusiform gyrus? , 2006, Behavioral neuroscience.

[52]  V. Goffaux,et al.  Spatio-temporal localization of the face inversion effect: an event-related potentials study , 1999, Biological Psychology.

[53]  G. Dawson,et al.  Prototype formation in autism , 2001, Development and Psychopathology.

[54]  Geraldine Dawson,et al.  Reduced neural habituation in the amygdala and social impairments in autism spectrum disorders. , 2009, The American journal of psychiatry.

[55]  A. Couteur,et al.  Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders , 1994, Journal of autism and developmental disorders.

[56]  James W. Tanaka,et al.  A Reevaluation of the Electrophysiological Correlates of Expert Object Processing , 2006, Journal of Cognitive Neuroscience.

[57]  Benjamin Balas,et al.  The role of face shape and pigmentation in other-race face perception: An electrophysiological study , 2010, Neuropsychologia.

[58]  Michael Murias,et al.  The Role of Face Familiarity in Eye Tracking of Faces by Individuals with Autism Spectrum Disorders , 2008, Journal of autism and developmental disorders.

[59]  Michael Murias,et al.  Response to familiar faces, newly familiar faces, and novel faces as assessed by ERPs is intact in adults with autism spectrum disorders. , 2010, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[60]  J. Piven,et al.  Visual Scanning of Faces in Autism , 2002, Journal of autism and developmental disorders.

[61]  A. Lee,et al.  What's in a face? The case of autism. , 1988, British journal of psychology.

[62]  R. Yin Looking at Upside-down Faces , 1969 .

[63]  T. Allison,et al.  Electrophysiological Studies of Face Perception in Humans , 1996, Journal of Cognitive Neuroscience.

[64]  T. Langdell,et al.  Recognition of faces: an approach to the study of autism. , 1978, Journal of child psychology and psychiatry, and allied disciplines.

[65]  F. Volkmar,et al.  Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism. , 2002, Archives of general psychiatry.

[66]  Kristen L. Merkle,et al.  Toddlers with Elevated Autism Symptoms Show Slowed Habituation to Faces , 2010, Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence.

[67]  Elinor McKone,et al.  Sensitivity of 4-year-olds to featural and second-order relational changes in face distinctiveness. , 2006, Journal of experimental child psychology.

[68]  A. Burton,et al.  N250r: a face-selective brain response to stimulus repetitions , 2004, Neuroreport.

[69]  J. J. Ryan,et al.  Wechsler Adult Intelligence Scale-III , 2001 .

[70]  S. Carey,et al.  Why faces are and are not special: an effect of expertise. , 1986 .