IGFBP-2 - taking the lead in growth, metabolism and cancer
暂无分享,去创建一个
G. Werther | W. Azar | S. Yau | V. Russo | M. Sabin | Walid J. Azar
[1] B. Cui,et al. Morphological and transcriptional responses of Lycopersicon esculentum to hexavalent chromium in agricultural soil , 2016, Environmental toxicology and chemistry.
[2] D. Ahlquist,et al. Colorectal Adenomas. , 2016, The New England journal of medicine.
[3] G. Werther,et al. IGFBP-2 - taking the lead in growth, metabolism and cancer , 2015, Journal of Cell Communication and Signaling.
[4] F. Dunshea,et al. IGFBP-2 inhibits adipogenesis and lipogenesis in human visceral, but not subcutaneous, adipocytes , 2014, International Journal of Obesity.
[5] D. Clemmons,et al. IGFBP‐2 Directly Stimulates Osteoblast Differentiation , 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[6] Kejiang Li,et al. Is insulin-like growth factor binding protein 2 associated with metastasis in lung cancer? , 2014, Clinical & Experimental Metastasis.
[7] G. McConell,et al. Leptin enhances insulin sensitivity by direct and sympathetic nervous system regulation of muscle IGFBP-2 expression: evidence from nonrodent models. , 2014, Endocrinology.
[8] S. Teo,et al. Loss of PTEN expression is associated with IGFBP2 expression, younger age, and late stage in triple-negative breast cancer. , 2014, American journal of clinical pathology.
[9] G. Werther,et al. IGFBP-2 nuclear translocation is mediated by a functional NLS sequence and is essential for its pro-tumorigenic actions in cancer cells , 2014, Oncogene.
[10] T. Thompson,et al. Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches , 2013, Oncogene.
[11] G. Mills,et al. Functional proteomics characterization of residual triple-negative breast cancer after standard neoadjuvant chemotherapy. , 2013, Annals of oncology : official journal of the European Society for Medical Oncology.
[12] Xifeng Wu,et al. Insulin-Like Growth Factor Binding Protein-2 Level Is Increased in Blood of Lung Cancer Patients and Associated with Poor Survival , 2013, PloS one.
[13] L. Maile,et al. The heparin-binding domains of IGFBP-2 mediate its inhibitory effect on preadipocyte differentiation and fat development in male mice. , 2013, Endocrinology.
[14] A. Ben-Ze'ev,et al. Global analysis of L1-transcriptomes identified IGFBP-2 as a target of ezrin and NF-κB signaling that promotes colon cancer progression , 2013, Oncogene.
[15] Mel Greaves,et al. Acute lymphoblastic leukaemia , 2013, The Lancet.
[16] S. Meshinchi,et al. Children's Oncology Group's 2013 blueprint for research: Acute myeloid leukemia , 2013, Pediatric blood & cancer.
[17] L. Zeng,et al. Insulin-like growth factor binding protein 2 (IGFBP-2) promotes growth and survival of breast epithelial cells: novel regulation of the estrogen receptor. , 2013, Endocrinology.
[18] L. Lo Nigro,et al. Biology of Childhood Acute Lymphoblastic Leukemia , 2013, Journal of pediatric hematology/oncology.
[19] Richard Aplenc,et al. Epidemiology of childhood acute myeloid leukemia , 2013, Pediatric blood & cancer.
[20] E. Estey,et al. Acute myeloid leukemia: 2013 update on risk‐stratification and management , 2013, American journal of hematology.
[21] J. Hernández-Rivas,et al. Chronic lymphocytic leukemia: a clinical and molecular heterogenous disease. , 2013, Cancer genetics.
[22] O. Nedić,et al. Interaction of Insulin-Like Growth Factor-Binding Protein 2 with α2-Macroglobulin in the Circulation , 2013, The Protein Journal.
[23] Qing Zhu,et al. Autoantibodies against insulin-like growth factor-binding protein-2 as a serological biomarker in the diagnosis of lung cancer , 2012, International journal of oncology.
[24] A. Smerieri,et al. Interactions among pro-inflammatory cytokines, IGF system and thyroid function in pre-pubertal obese subjects. , 2013, Journal of biological regulators and homeostatic agents.
[25] H. Kantarjian,et al. Chronic myeloid leukemia: 2012 update on diagnosis, monitoring, and management , 2012, American journal of hematology.
[26] L. Maile,et al. Insulin-Like Growth Factor (IGF) Binding Protein 2 Functions Coordinately with Receptor Protein Tyrosine Phosphatase β and the IGF-I Receptor To Regulate IGF-I-Stimulated Signaling , 2012, Molecular and Cellular Biology.
[27] Konrad Basler,et al. The many faces and functions of β‐catenin , 2012, The EMBO journal.
[28] Mohammed Shanshal,et al. Chronic lymphocytic leukemia. , 2012, Disease-a-month : DM.
[29] R. Norton,et al. Insulin-like growth factor binding protein-2: NMR analysis and structural characterization of the N-terminal domain. , 2012, Biochimie.
[30] L. Maile,et al. Insulin‐like growth factor‐binding protein‐2 is required for osteoclast differentiation , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[31] 優花 竹之内. Insulin-Like Growth Factor-Binding Protein 2 , 2012 .
[32] J. Ko,et al. Influence of catch-up growth on IGFBP-2 levels and association between IGFBP-2 and cardiovascular risk factors in Korean children born SGA. , 2012, Endocrine journal.
[33] K. Basler,et al. Focus Review The many faces and functions of b-catenin , 2012 .
[34] W. Carroll,et al. Clinical and laboratory biology of childhood acute lymphoblastic leukemia. , 2012, The Journal of pediatrics.
[35] A. Smerieri,et al. Effects of Cord Serum Insulin, IGF-II, IGFBP-2, IL-6 and Cortisol Concentrations on Human Birth Weight and Length: Pilot Study , 2011, PloS one.
[36] P. Hillmen. Using the biology of chronic lymphocytic leukemia to choose treatment. , 2011, Hematology. American Society of Hematology. Education Program.
[37] C. Bloomfield,et al. High expression of IGFBP2 is associated with chemoresistance in adult acute myeloid leukemia. , 2011, Leukemia research.
[38] F. Dunshea,et al. Dietary Monounsaturated Fat in Early Life Regulates IGFBP2: Implications for Fat Mass Accretion and Insulin Sensitivity , 2011, Obesity.
[39] J. Rowley,et al. Chronic myeloid leukemia: current perspectives. , 2011, Clinics in laboratory medicine.
[40] A. Hoffman,et al. IGFBP-2 enhances VEGF gene promoter activity and consequent promotion of angiogenesis by neuroblastoma cells. , 2011, Endocrinology.
[41] K. Brismar,et al. Neutrophil-derived azurocidin cleaves insulin-like growth factor-binding protein-1, -2 and -4. , 2011, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
[42] W. Kiess,et al. IGFBP-2 at the interface of growth and metabolism--implications for childhood obesity. , 2011, Pediatric endocrinology reviews : PER.
[43] D. Larhammar,et al. Evolution of the insulin-like growth factor binding protein (IGFBP) family. , 2011, Endocrinology.
[44] D. Gillatt,et al. Insulin-like growth factor-binding protein-2 promotes prostate cancer cell growth via IGF-dependent or -independent mechanisms and reduces the efficacy of docetaxel , 2011, British Journal of Cancer.
[45] M. Bouxsein,et al. The Heparin-binding Domain of IGFBP-2 Has Insulin-like Growth Factor Binding-independent Biologic Activity in the Growing Skeleton* , 2011, The Journal of Biological Chemistry.
[46] Bonadonna Riccardo,et al. Adipocytes IGFBP‐2 Expression in Prepubertal Obese Children , 2010, Obesity.
[47] M. Waters,et al. Patched1 Inhibits Epidermal Progenitor Cell Expansion and Basal Cell Carcinoma Formation by Limiting Igfbp2 Activity , 2010, Cancer Prevention Research.
[48] F. Picard,et al. Modulation of IGFBP2 mRNA expression in white adipose tissue upon aging and obesity. , 2010, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[49] A. Hoeflich,et al. Increased fat mass, decreased myofiber size, and a shift to glycolytic muscle metabolism in adolescent male transgenic mice overexpressing IGFBP-2. , 2010, American journal of physiology. Endocrinology and metabolism.
[50] G. Fuller,et al. JNK mediates insulin-like growth factor binding protein 2/integrin alpha5-dependent glioma cell migration. , 2010, International journal of oncology.
[51] Hsiu‐Po Wang,et al. Plasma insulin-like growth factor-binding protein-2 levels as diagnostic and prognostic biomarker of colorectal cancer. , 2010, The Journal of clinical endocrinology and metabolism.
[52] Y. Ishikawa,et al. Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma: IGF-independent antiapoptotic effect via caspase-3. , 2010, The American journal of pathology.
[53] M. Pollak,et al. IGFBP‐2 Expression in MCF‐7 Cells is Regulated by the PI3K/AKT/mTOR Pathway through Sp1 Induced Increase in Transcription , 2010, Growth factors.
[54] A. Hokken-Koelega,et al. Serum insulin-like growth factor-binding protein-2 levels and metabolic and cardiovascular risk factors in young adults and children born small for gestational age. , 2010, The Journal of clinical endocrinology and metabolism.
[55] R. Wysocki,et al. Antidiabetic effects of IGFBP2, a leptin-regulated gene. , 2010, Cell metabolism.
[56] G. Fuller,et al. IGFBP2 is a candidate biomarker for Ink4a-Arf status and a therapeutic target for high-grade gliomas , 2009, Proceedings of the National Academy of Sciences.
[57] Takashi Takahashi,et al. Neuroendocrine cancer-specific up-regulating mechanism of insulin-like growth factor binding protein-2 in small cell lung cancer. , 2009, The American journal of pathology.
[58] G. Werther,et al. Activation of a prometastatic gene expression program in hypoxic neuroblastoma cells. , 2009, Endocrine-related cancer.
[59] A. Hoeflich,et al. IGFBP‐2 overexpression reduces the appearance of dysplastic aberrant crypt foci and inhibits growth of adenomas in chemically induced colorectal carcinogenesis , 2009, International journal of cancer.
[60] H. Ariga,et al. PAPA-1 Is a nuclear binding partner of IGFBP-2 and modulates its growth-promoting actions. , 2009, Molecular endocrinology.
[61] R. Sikes,et al. Disease evidence for IGFBP-2 as a key player in prostate cancer progression and development of osteosclerotic lesions. , 2009, American journal of translational research.
[62] A. Hoeflich,et al. Defined carboxy-terminal fragments of insulin-like growth factor (IGF) binding protein-2 exert similar mitogenic activity on cultured rat growth plate chondrocytes as IGF-I. , 2008, Endocrinology.
[63] S. Khatua,et al. IGFBP2 Is Overexpressed by Pediatric Malignant Astrocytomas and Induces the Repair Enzyme DNA-PK , 2008, Journal of Child Neurology.
[64] M. Bouxsein,et al. Gender-specific changes in bone turnover and skeletal architecture in igfbp-2-null mice. , 2008, Endocrinology.
[65] G. Fuller,et al. IGFBP2 and IGFBP5 Overexpression Correlates With the Lymph Node Metastasis in T1 Breast Carcinomas , 2008, The breast journal.
[66] S. Li,et al. A functional nuclear localization signal in insulin-like growth factor binding protein-6 mediates its nuclear import. , 2008, Endocrinology.
[67] D. Steinbach,et al. Expression of components of the IGF axis in childhood acute myelogenous leukemia , 2008, Pediatric blood & cancer.
[68] M. Ueffing,et al. Functional Proteomics , 2008, Methods in Molecular Biology.
[69] Hiroaki Kataoka,et al. Roles of insulin-like growth factor binding protein-2 (IGFBP-2) in glioblastoma. , 2007, Anticancer research.
[70] L. Rejtõ,et al. Hormonal regulation of IGFBP‐2 proteolysis is attenuated with progression to androgen insensitivity in the LNCaP progression model , 2007, Journal of cellular physiology.
[71] C. Perks,et al. IGF-II and IGFBP-2 differentially regulate PTEN in human breast cancer cells , 2007, Oncogene.
[72] R. Baxter,et al. The in Vivo Phosphorylation and Glycosylation of Human Insulin-like Growth Factor-binding Protein-5 *S , 2007, Molecular & Cellular Proteomics.
[73] S. Nakano,et al. Silencing of Insulin-like Growth Factor-binding Protein-2 in Human Glioblastoma Cells Reduces Both Invasiveness and Expression of Progression-associated Gene CD24* , 2007, Journal of Biological Chemistry.
[74] R. Baxter,et al. Expression of insulin-like growth factor binding protein-2 by MCF-7 breast cancer cells is regulated through the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway. , 2007, Endocrinology.
[75] K. Yano,et al. Matrix metalloproteinase‐7 triggers the matricrine action of insulin‐like growth factor‐II via proteinase activity on insulin‐like growth factor binding protein 2 in the extracellular matrix , 2007, Cancer science.
[76] S. Horvath,et al. Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer , 2007, Proceedings of the National Academy of Sciences.
[77] Antonio Vidal-Puig,et al. IGF-Binding Protein-2 Protects Against the Development of Obesity and Insulin Resistance , 2007, Diabetes.
[78] M. Krawczuk-Rybak,et al. Are elevated serum levels of IGFBP-2 after intensive chemotherapy of childhood acute lymphoblastic leukemia a risk factor of relapse? , 2007, Advances in medical sciences.
[79] R. Norton,et al. Structure, dynamics and heparin binding of the C-terminal domain of insulin-like growth factor-binding protein-2 (IGFBP-2). , 2006, Journal of molecular biology.
[80] S. Mohan,et al. Pregnancy-associated plasma protein-A increases osteoblast proliferation in vitro and bone formation in vivo. , 2006, Endocrinology.
[81] T. Burns,et al. Insulin-like growth factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling , 2006, Cancer biology & therapy.
[82] G. Fuller,et al. Insulin-like growth factor-binding protein 2 and 5 are differentially regulated in ovarian cancer of different histologic types , 2006, Modern Pathology.
[83] A. Hoeflich,et al. IGF-independent effects of IGFBP-2 on the human breast cancer cell line Hs578T. , 2006, Journal of molecular endocrinology.
[84] A. Lykkesfeldt,et al. Insulin-like growth factor binding protein 2 is a marker for antiestrogen resistant human breast cancer cell lines but is not a major growth regulator. , 2006, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
[85] S. Anderson,et al. Insulin-like growth factor binding protein-2 (IGFBP-2) is a marker for the metabolic syndrome. , 2006, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.
[86] B. Gruhn,et al. Elevated serum insulin-like growth factor binding protein-2 is associated with a high relapse risk after hematopoietic stem cell transplantation in childhood AML , 2006, Bone Marrow Transplantation.
[87] A. Suminoe,et al. IDENTIFICATION OF NOVEL GENES WITH PROGNOSTIC VALUE IN CHILDHOOD LEUKEMIA USING cDNA MICROARRAY AND QUANTITATIVE RT-PCR , 2006, Pediatric hematology and oncology.
[88] S. Corroyer,et al. Intracellular colocalization and interaction of IGF-binding protein-2 with the cyclin-dependent kinase inhibitor p21CIP1/WAF1 during growth inhibition. , 2005, The Biochemical journal.
[89] C. Dealy,et al. Role of IGFBP2, IGF-I and IGF-II in regulating long bone growth. , 2005, Bone.
[90] M. Georgescu,et al. PTEN-induction in U251 glioma cells decreases the expression of insulin-like growth factor binding protein-2. , 2005, Biochemical and biophysical research communications.
[91] A. Hoeflich,et al. Insulin-like growth factor binding protein-2 binding to extracellular matrix plays a critical role in neuroblastoma cell proliferation, migration, and invasion. , 2005, Endocrinology.
[92] W. Blum,et al. Insulin-like growth factor binding protein-2 at diagnosis of childhood acute lymphoblastic leukemia and the prediction of relapse risk. , 2005, The Journal of clinical endocrinology and metabolism.
[93] Tadashi Kondo,et al. Morphological and transcriptional responses of untransformed intestinal epithelial cells to an oncogenic β-catenin protein , 2005, Oncogene.
[94] Thomas Braulke,et al. Diversity of human insulin-like growth factor (IGF) binding protein-2 fragments in plasma: primary structure, IGF-binding properties, and disulfide bonding pattern. , 2005, Biochemistry.
[95] W. Blum,et al. Serum levels of insulin-like growth factor-I,-II and insulin-like growth factor binding proteins-2 and-3 in children with acute lymphoblastic leukaemia , 1996, European Journal of Pediatrics.
[96] I. Shmulevich,et al. Insulin-like growth factor binding protein 2 promotes ovarian cancer cell invasion , 2005, Molecular Cancer.
[97] A. Hoeflich,et al. Peri/nuclear localization of intact insulin-like growth factor binding protein-2 and a distinct carboxyl-terminal IGFBP-2 fragment in vivo. , 2004, Biochemical and biophysical research communications.
[98] M. Overgaard,et al. Proteolytic degradation of IGF-binding protein (IGFBP)-2 in equine ovarian follicles: involvement of pregnancy-associated plasma protein-A (PAPP-A) and association with dominant but not subordinated follicles. , 2004, The Journal of endocrinology.
[99] G. Rao,et al. Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice , 2004, Oncogene.
[100] D. Newgreen,et al. Fibroblast growth factor‐2 over‐rides insulin‐like growth factor‐I induced proliferation and cell survival in human neuroblastoma cells , 2004, Journal of cellular physiology.
[101] M. Elmlinger,et al. Integrin-mediated action of insulin-like growth factor binding protein-2 in tumor cells. , 2004, Journal of molecular endocrinology.
[102] E. Gazzerro,et al. Potentiating role of IGFBP-2 on IGF-II-stimulated alkaline phosphatase activity in differentiating osteoblasts. , 2004, American journal of physiology. Endocrinology and metabolism.
[103] C. Heinlein,et al. Androgen receptor in prostate cancer. , 2004, Endocrine reviews.
[104] Joseph J. Pereira,et al. Bimolecular Interaction of Insulin-Like Growth Factor (IGF) Binding Protein-2 with αvβ3 Negatively Modulates IGF-I-Mediated Migration and Tumor Growth 1 , 2004, Cancer Research.
[105] L. Sepp-Lorenzino. Structure and function of the insulin-like growth factor I receptor , 1998, Breast Cancer Research and Treatment.
[106] J. Heinrich,et al. Differential Impact of Simple Childhood Obesity on the Components of the Growth Hormone-Insulin-like Growth Factor (IGF)-IGF Binding Proteins Axis , 2004, Journal of pediatric endocrinology & metabolism : JPEM.
[107] G. Fuller,et al. IIp45, an insulin-like growth factor binding protein 2 (IGFBP-2) binding protein, antagonizes IGFBP-2 stimulation of glioma cell invasion , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[108] G. Semenza. Targeting HIF-1 for cancer therapy , 2003, Nature Reviews Cancer.
[109] G. Krassas. Endocrine abnormalities in Anorexia Nervosa. , 2003, Pediatric endocrinology reviews : PER.
[110] G. Fuller,et al. Insulin-like growth factor binding protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes. , 2003, Cancer research.
[111] F. Zintl,et al. Changes of serum growth factors (IGF-I,-II and IGFBP-2,-3) prior to and after stem cell transplantation in children with acute leukemia , 2003, Bone Marrow Transplantation.
[112] T. Bek,et al. The relationship between the circulating IGF system and the presence of retinopathy in Type 1 diabetic patients , 2003, Diabetic medicine : a journal of the British Diabetic Association.
[113] R. Baxter,et al. Cellular actions of the insulin-like growth factor binding proteins. , 2002, Endocrine reviews.
[114] A. Hoeflich,et al. Insulin-like growth factor-binding protein-2 (IGFBP-2) overexpression negatively regulates bone size and mass, but not density, in the absence and presence of growth hormone/IGF-I excess in transgenic mice , 2002, Anatomy and Embryology.
[115] S. Khosla,et al. Subcutaneous administration of insulin-like growth factor (IGF)-II/IGF binding protein-2 complex stimulates bone formation and prevents loss of bone mineral density in a rat model of disuse osteoporosis. , 2002, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
[116] M. Rechler,et al. Insulin‐like growth factor binding protein‐2 mediates the inhibition of DNA synthesis by transforming growth factor‐β in mink lung epithelial cells * † , 2002, Journal of cellular physiology.
[117] Adrian L. Harris,et al. Hypoxia — a key regulatory factor in tumour growth , 2002, Nature Reviews Cancer.
[118] A. Hoeflich,et al. Growth Inhibition in Giant Growth Hormone Transgenic Mice by Overexpression of Insulin-Like Growth Factor-Binding Protein-2. , 2001, Endocrinology.
[119] S. Bustin,et al. Increased levels of insulin‐like growth factor binding protein‐2 in sera and tumours from patients with colonic neoplasia with and without acromegaly , 2001, Clinical endocrinology.
[120] Y. Maru. Molecular Biology of Chronic Myeloid Leukemia , 2001, International journal of hematology.
[121] E. Nabeyrat,et al. Distinct patterns of insulin-like growth factor binding protein (IGFBP)-2 and IGFBP-3 expression in oxidant exposed lung epithelial cells. , 2001, Biochimica et biophysica acta.
[122] J. Argente,et al. Insulin-Like Growth Factor-Binding Protein-2 Levels in Pediatric Patients with Growth Hormone Deficiency, Eating Disorders and Acute Lymphoblastic Leukemia , 2000, Hormone Research in Paediatrics.
[123] T. Wood,et al. Selective alterations in organ sizes in mice with a targeted disruption of the insulin-like growth factor binding protein-2 gene. , 2000, Molecular endocrinology.
[124] C. Potten,et al. The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2000 by The Endocrine Society Circulating Insulin-Like Growth Factor II and , 2000 .
[125] R. Baxter,et al. Nuclear Import of Insulin-like Growth Factor-binding Protein-3 and -5 Is Mediated by the Importin β Subunit* , 2000, The Journal of Biological Chemistry.
[126] J Straub,et al. APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits". , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[127] M. Hotta,et al. The relationship between bone turnover and body weight, serum insulin-like growth factor (IGF) I, and serum IGF-binding protein levels in patients with anorexia nervosa. , 2000, The Journal of clinical endocrinology and metabolism.
[128] R. Baxter,et al. A Central Domain Binding Site in Insulin-Like Growth Factor Binding Protein-5 for the Acid-Labile Subunit. , 2000, Endocrinology.
[129] J. Frystyk,et al. Circulating levels of free insulin‐like growth factors in obese subjects: the impact of Type 2 diabetes , 1999, Diabetes/metabolism research and reviews.
[130] G. Semenza,et al. Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2. , 1999, Cancer research.
[131] S. J. Kim,et al. Serum insulin-like growth factor (IGF)-I and IGF-binding proteins in lung cancer patients. , 1999, Journal of Korean medical science.
[132] G. Werther,et al. Basic fibroblast growth factor induces proteolysis of secreted and cell membrane-associated insulin-like growth factor binding protein-2 in human neuroblastoma cells. , 1999, Endocrinology.
[133] C. Lang,et al. Alterations in the Growth Hormone-Insulin-Like Growth Factor Axis in Insulin Dependent Diabetes Mellitus , 1999, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[134] A. Hoeflich,et al. Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain. , 1999, Endocrinology.
[135] G. Semenza,et al. Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. , 1999, Annual review of cell and developmental biology.
[136] T. Braulke. Type-2 IGF Receptor: A Multi-Ligand Binding Protein , 1999, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[137] A. Sidawy,et al. Role of insulin-like growth factor-I (IGF-I) receptor, IGF-I, and IGF binding protein-2 in human colorectal cancers. , 1998, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
[138] J. Halaas,et al. Leptin and the regulation of body weight in mammals , 1998, Nature.
[139] E. Wolf,et al. Insulin‐like growth factor‐binding protein‐2 inhibits proliferation of human embryonic kidney fibroblasts and of IGF‐responsive colon carcinoma cell lines , 1998, FEBS letters.
[140] W. Blum,et al. Elevated serum levels of IGFBP-2 found in children suffering from acute leukaemia is accompanied by the occurrence of IGFBP-2 mRNA in the tumour clone. , 1998, British Journal of Cancer.
[141] A. Burgess,et al. Growth control mechanisms in normal and transformed intestinal cells. , 1998, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[142] A. Hoeflich,et al. Altered growth of mice divergently selected for body weight is associated with complex changes in the growth hormone/insulin-like growth factor system. , 1998, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
[143] M. Elmlinger,et al. Elevated insulin-like growth factor (IGF) binding protein (IGFBP)-2 and IGFBP-4 expression of leukemic T-cells is affected by autocrine/paracrine IGF-II action but not by IGF type I receptor expression. , 1998, European journal of endocrinology.
[144] J. Wallace,et al. Localization of an Insulin-like Growth Factor (IGF) Binding Site of Bovine IGF Binding Protein-2 Using Disulfide Mapping and Deletion Mutation Analysis of the C-terminal Domain* , 1998, The Journal of Biological Chemistry.
[145] D. Halliday,et al. Changes in protein turnover, IGF‐I and IGF binding proteins in children with cancer , 1998, Acta paediatrica.
[146] R. Baxter,et al. Characterization of truncated insulin-like growth factor-binding protein-2 in human milk. , 1997, Endocrinology.
[147] Y. Song,et al. Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone , 1997, International Journal of Obesity.
[148] R. Baxter,et al. Phosphorylation of insulin-like growth factor binding proteins , 1997, Molecular and Cellular Endocrinology.
[149] R. Baxter,et al. Insulin‐like growth factor‐binding protein‐2 in patients with prostate carcinoma and benign prostatic hyperplasia , 1997, Clinical endocrinology.
[150] M. Langman,et al. Insulin-like growth factors and their binding proteins in human colonocytes: preferential degradation of insulin-like growth factor binding protein 2 in colonic cancers. , 1997, British Journal of Cancer.
[151] M. Elmlinger,et al. Insulin-like growth factor binding protein 2 is differentially expressed in leukaemic B- and T-cell lines. , 1996, Growth regulation.
[152] A. Karasik,et al. Increased insulin-like growth factor binding protein-2 (IGFBP-2) gene expression and protein production lead to high IGFBP-2 content in malignant ovarian cyst fluid. , 1996, British Journal of Cancer.
[153] D. Clemmons,et al. Substitution of Specific Amino Acids in Insulin-like Growth Factor (IGF) Binding Protein 5 Alters Heparin Binding and Its Change in Affinity for IGF-I in Response to Heparin (*) , 1996, The Journal of Biological Chemistry.
[154] S. Mohan,et al. Insulin‐Like Growth Factor (IGF) System Components in Human Prostatic Cancer Cell‐Lines: LNCaP, DU145, and PC‐3 Cells , 1996, International journal of urology : official journal of the Japanese Urological Association.
[155] E Ruoslahti,et al. RGD and other recognition sequences for integrins. , 1996, Annual review of cell and developmental biology.
[156] T. Wood,et al. Genetic approaches to the function of insulin-like growth factor-binding proteins during rodent development. , 1996, Hormone research.
[157] J. Thrasher,et al. Insulin-like growth factor-binding protein-2 and -3 expression in benign human prostate epithelium, prostate intraepithelial neoplasia, and adenocarcinoma of the prostate. , 1996, The Journal of clinical endocrinology and metabolism.
[158] K. Iwasaki,et al. Identification and characterization of insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), and IGFBP proteases in human synovial fluid. , 1996, The Journal of clinical endocrinology and metabolism.
[159] K. Tatemoto,et al. Synthesis and secretion of insulin-like growth factor (IGF)-II and IGF binding protein-2 by cultivated brain meningeal cells , 1995, Brain Research.
[160] M. Corkins,et al. Growth stimulation by transfection of intestinal epithelial cells with an antisense insulin-like growth factor binding protein-2 construct. , 1995, Biochemical and biophysical research communications.
[161] C. Bondy,et al. Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis. , 1995, Endocrinology.
[162] L. Giudice,et al. Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth. , 1995, The Journal of clinical endocrinology and metabolism.
[163] G. Werther,et al. Cell membrane association of insulin-like growth factor binding protein-2 (IGFBP-2) in the rat brain olfactory bulb. , 1995, Progress in growth factor research.
[164] K. Shitara,et al. Brain-specific receptor-type protein-tyrosine phosphatase RPTP beta is a chondroitin sulfate proteoglycan in vivo. , 1994, The Journal of biological chemistry.
[165] F. Garrouste,et al. Alterations in serum levels of insulin‐like growth factors and insulin‐like growth‐factor‐binding proteins in patients with colorectal cancer , 1994, International journal of cancer.
[166] S. Sallan,et al. Biology and therapy of childhood acute lymphoblastic leukemia. , 1994, Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion.
[167] A. Karasik,et al. Insulin-like growth factor-I (IGF-I) and IGF-binding protein-2 are increased in cyst fluids of epithelial ovarian cancer. , 1994, The Journal of clinical endocrinology and metabolism.
[168] K. Siddle,et al. Hybrid and atypical insulin/insulin-like growth factor I receptors. , 1994, Hormone research.
[169] D. Clemmons,et al. The effect of dietary protein supplementation on insulin-like growth factors (IGFs) and IGF-binding proteins in children with shigellosis. , 1993, The Journal of clinical endocrinology and metabolism.
[170] N. Bleehen,et al. Role for membrane and secreted insulin-like growth factor-binding protein-2 in the regulation of insulin-like growth factor action in lung tumors. , 1993, Cancer research.
[171] D. DiGregorio,et al. Growth factor modulation of insulin-like growth factor-binding proteins in rat osteoblast-like cells. , 1993, Endocrinology.
[172] T. Stamey,et al. Elevated levels of insulin-like growth factor-binding protein-2 in the serum of prostate cancer patients. , 1993, The Journal of clinical endocrinology and metabolism.
[173] M. Waters,et al. of Insulin-Like Growth , 1993 .
[174] L. Carlsson,et al. The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins. , 1992, The Journal of clinical endocrinology and metabolism.
[175] J. G. Reeve,et al. Insulin‐like growth‐factor‐binding protein gene expression and protein production by human tumour cell lines , 1992, International journal of cancer.
[176] N. Bleehen,et al. Expression of insulinlike growth factor (IGF) and IGF-binding protein genes in human lung tumor cell lines. , 1992, Journal of the National Cancer Institute.
[177] J. Gordon,et al. The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system , 1992, The Journal of cell biology.
[178] R. Vigneri,et al. High-affinity insulin binding to an atypical insulin-like growth factor-I receptor in human breast cancer cells. , 1992, The Journal of clinical investigation.
[179] G. Jaques,et al. Differential expression of insulin-like growth factor binding proteins in human non-small cell lung cancer cell lines. , 1992, European journal of cancer.
[180] J. Perdue,et al. The design, expression, and characterization of human insulin-like growth factor II (IGF-II) mutants specific for either the IGF-II/cation-independent mannose 6-phosphate receptor or IGF-I receptor. , 1991, The Journal of biological chemistry.
[181] L. Giudice,et al. Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the puerperium: effects of a pregnancy-associated serum protease activity. , 1990, The Journal of clinical endocrinology and metabolism.
[182] R. Humbel,et al. Insulin-like growth factors I and II. , 1990, European journal of biochemistry.
[183] V. Duronio,et al. Insulin-like growth factor I receptor beta-subunit heterogeneity. Evidence for hybrid tetramers composed of insulin-like growth factor I and insulin receptor heterodimers. , 1989, The Journal of biological chemistry.
[184] D. Chelsky,et al. Sequence requirements for synthetic peptide-mediated translocation to the nucleus , 1989, Molecular and cellular biology.
[185] P. Rotwein,et al. Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. , 1989, Endocrine reviews.
[186] K. Hall,et al. Serum levels of the low molecular weight form of insulin-like growth factor binding protein in healthy subjects and patients with growth hormone deficiency, acromegaly and anorexia nervosa. , 1988, Acta endocrinologica.
[187] V. Han,et al. Cellular localization of somatomedin (insulin-like growth factor) messenger RNA in the human fetus. , 1987, Science.
[188] G. Bell,et al. Tissue distribution of insulin-like growth factor I and II messenger ribonucleic acid in the adult rat. , 1987, Endocrinology.
[189] E. Froesch,et al. Insulin-like growth factors/somatomedins: structure, secretion, biological actions and physiological role. , 1986, Hormone research.