Problem substance use among depressed patients in managed primary care.

This study identifies characteristics associated with problem substance use among 1,187 patients with either depressive symptoms (44%) or depressive disorders (56%) in primary care clinics of six managed care organizations. Sedative misuse (reported by 14% of all patients) was associated with greater wealth, social phobia, and misuse of prescription opioids. Cannabis use (11%) was associated with younger age, male gender, single marital status, white ethnicity, less education, recurrent depression, agoraphobia, and hazardous alcohol use. Hazardous drinking (11%) was significantly associated with younger age, male gender, single marital status, and cannabis use. Greater understanding of substance use problems in primary care patients with depressive symptoms and disorders may aid efforts to more quickly identify, educate, and provide services for those in need.

[1]  P. O'Connor,et al.  Hazardous and harmful alcohol consumption in primary care. , 1999, Archives of internal medicine.

[2]  D. Nutt,et al.  Consensus statement on the primary care management of depression from the International Consensus Group on Depression and Anxiety. , 1999, The Journal of clinical psychiatry.

[3]  R. Baldessarini,et al.  Suicide attempts in major affective disorder patients with comorbid substance use disorders. , 1999, The Journal of clinical psychiatry.

[4]  A. Rush,et al.  Treating major depression in primary care practice: an update of the Agency for Health Care Policy and Research Practice Guidelines. , 1998, Archives of general psychiatry.

[5]  A. Schatzberg,et al.  Prevalence of anxiety disorders and their comorbidity with mood and addictive disorders , 1998, British Journal of Psychiatry.

[6]  Joseph L Schafer,et al.  Analysis of Incomplete Multivariate Data , 1997 .

[7]  D. Ziedonis,et al.  Dual diagnosis in primary care. Detecting and treating both the addiction and mental illness. , 1997, The Medical clinics of North America.

[8]  C. Sherbourne,et al.  Comorbid anxiety disorder and the functioning and well-being of chronically ill patients of general medical providers. , 1996, Archives of general psychiatry.

[9]  R. Kessler,et al.  Comorbidity of DSM–III–R Major Depressive Disorder in the General Population: Results from the US National Comorbidity Survey , 1996, British Journal of Psychiatry.

[10]  D. Rubin Multiple Imputation After 18+ Years , 1996 .

[11]  W. Hall,et al.  The AUDIT questionnaire: choosing a cut-off score. Alcohol Use Disorder Identification Test. , 1995, Addiction.

[12]  R. Kessler,et al.  Prevalence and correlates of drug use and dependence in the United States. Results from the National Comorbidity Survey. , 1995, Archives of general psychiatry.

[13]  Ronald C. Kessler,et al.  Comparative epidemiology of dependence on tobacco, alcohol, controlled substances, and inhalants: Basic findings from the National Comorbidity Survey. , 1994 .

[14]  O. Aasland,et al.  Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO Collaborative Project on Early Detection of Persons with Harmful Alcohol Consumption--II. , 1993, Addiction.

[15]  K. Rost,et al.  Development of Screeners for Depressive Disorders and Substance Disorder History , 1993, Medical care.

[16]  F. Goodwin,et al.  The de facto US mental and addictive disorders service system. Epidemiologic catchment area prospective 1-year prevalence rates of disorders and services. , 1993, Archives of general psychiatry.

[17]  D S Rae,et al.  Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. , 1990, JAMA.

[18]  S. Ha Spectrum of drinkers and intervention opportunities , 1990 .

[19]  J. Khalsa,et al.  Hispanics and illicit drug use: a review of recent findings. , 1990, The International journal of the addictions.

[20]  K. Wells,et al.  Chronic medical conditions in a sample of the general population with anxiety, affective, and substance use disorders. , 1989, The American journal of psychiatry.

[21]  D. Rubin Multiple imputation for nonresponse in surveys , 1989 .

[22]  H. Schulberg,et al.  Recognition of alcoholism and substance abuse in primary care patients. , 1987, Archives of internal medicine.

[23]  G. Woody,et al.  Predicting response to alcohol and drug abuse treatments. Role of psychiatric severity. , 1983, Archives of general psychiatry.

[24]  K. Wells The design of Partners in Care: evaluating the cost-effectiveness of improving care for depression in primary care , 1999, Social Psychiatry and Psychiatric Epidemiology.

[25]  W. Katon,et al.  Collaborative management to achieve depression treatment guidelines. , 1997, The Journal of clinical psychiatry.

[26]  K. Barry,et al.  Brief physician advice for problem alcohol drinkers. A randomized controlled trial in community-based primary care practices. , 1997, JAMA.

[27]  C. Sherbourne,et al.  Caring for depression , 1996 .

[28]  A. Roche,et al.  Doctors' willingness to intervene in patients' drug and alcohol problems. , 1991, Social science & medicine.

[29]  E. Neira-Munoz,et al.  A survey of general practitioners' opinion and attitude to drug addicts and addiction. , 1990, British journal of addiction.