Improving the limit of detection (LOD) of microsensor used in detection of brain diseases via wavelet filter

Limit of detection (LOD) gives the concentration amount that a microsensor can detect. It is desirable to have a LOD value of 1μM for microsensors used in brain diseases. The ones that cannot reach this sensitivity value are disposed and cannot be used in the experiments. The goal of this study is to increase the sensitivity of the produced microsensors by decreasing their LOD values. LOD increases linearly by baseline noise. The sensor data is used generally without any baseline filtering in the literature. In this study, LOD values are enhanced 3 times as much by using wavelet filtering, compared with the ones where no filtering is used.