Sporadic Burkitt's lymphoma of the jaws: the essentials of prompt life-saving referral and management.

Burkitt's lymphoma is an undifferentiated non-Hodgkin's B-cell lymphoma. Three clinical subtypes are recognized: African (endemic), American (sporadic) and HIV associated. Sporadic Burkitt's lymphoma is a rare malignancy among western populations. This report describes a case of sporadic Burkitt's lymphoma of the jaws with an alarmingly rapid spread associated with acute renal failure. This type of rapid progression bespeaks the need for prompt recognition and life-saving referral by the dental practitioner. The clinical features of Burkitt's lymphoma involving the jaws include severely hypermobile, ectopically displaced and supra-erupted teeth. The purpose of this case report and review of the literature is to illustrate the clinical and histopathologic features of Burkitt's lymphoma to help clinicians recognize such cases readily and facilitate prompt and potentially life-saving referral.

[1]  E. Durmuş,et al.  Intraosseous mandibular lesion. , 2003, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[2]  H. Takada,et al.  Immunological aspects of Epstein-Barr virus infection. , 2002, Critical reviews in oncology/hematology.

[3]  A. Carbone.  AIDS-related non-Hodgkin's lymphomas: from pathology and molecular pathogenesis to treatment. , 2002, Human pathology.

[4]  W. Hammerschmidt,et al.  Molecular virology of Epstein-Barr virus. , 2001, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[5]  R. Landesberg,et al.  Unilateral mandibular lip anesthesia as the sole presenting symptom of Burkitt's lymphoma: case report and review of literature. , 2001, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[6]  J. Cohen,et al.  Epstein-Barr virus infection. , 2000, The New England journal of medicine.

[7]  W. Lam,et al.  Burkitt's lymphoma presenting as mandibular swelling--report of a case and review of publications. , 2000, The British journal of oral & maxillofacial surgery.

[8]  D. Laufer,et al.  Burkitt's lymphoma of the oral cavity in Israel. , 1999, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[9]  J. Downing,et al.  Non-Hodgkin's lymphoma in childhood. , 1996, The New England journal of medicine.

[10]  C. Sample,et al.  Epstein-Barr Virus DNA recombination and loss in sporadic Burkitt's lymphoma. , 1996, The Journal of infectious diseases.

[11]  W. Neville,et al.  Oral and Maxillofacial Pathology , 2004 .

[12]  D. Burkitt.  A sarcoma involving the jaws in african children , 1972, The British journal of surgery.

[13]  M. Epstein,et al.  VIRUS PARTICLES IN CULTURED LYMPHOBLASTS FROM BURKITT'S LYMPHOMA. , 1964, Lancet.

[14]  D. Burkitt,et al.  A sarcoma involving the jaws in african children , 1958, CA: a cancer journal for clinicians.

[15]  A. Kacker,et al.  Sporadic Burkitt's lymphoma of the head and neck in the pediatric population. , 2003, International journal of pediatric otorhinolaryngology.

[16]  A. Carbone.  Emerging pathways in the development of AIDS-related lymphomas. , 2003, The Lancet. Oncology.

[17]  J. Shapira,et al.  Burkitt's lymphoma. , 1998, Oral oncology.