JC polyomavirus attachment, entry, and trafficking: unlocking the keys to a fatal infection

[1]  P. An,et al.  Identification of a novel polyomavirus in a pancreatic transplant recipient with retinal blindness and vasculitic myopathy. , 2014, The Journal of infectious diseases.

[2]  L. Johannes,et al.  Rab7 Is Functionally Required for Selective Cargo Sorting at the Early Endosome , 2014, Traffic.

[3]  A. Lipovsky,et al.  A Retrograde Trafficking Inhibitor of Ricin and Shiga-Like Toxins Inhibits Infection of Cells by Human and Monkey Polyomaviruses , 2013, mBio.

[4]  M. Maginnis,et al.  5-HT2 Receptors Facilitate JC Polyomavirus Entry , 2013, Journal of Virology.

[5]  T. Stehle,et al.  A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus , 2013, PLoS pathogens.

[6]  H. Hirsch,et al.  The human polyomaviruses: from orphans and mutants to patchwork family , 2013, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[7]  A. Hakansson,et al.  Interkingdom Signaling Induces Streptococcus pneumoniae Biofilm Dispersion and Transition from Asymptomatic Colonization to Disease , 2013, mBio.

[8]  T. Stehle,et al.  Progressive Multifocal Leukoencephalopathy-Associated Mutations in the JC Polyomavirus Capsid Disrupt Lactoseries Tetrasaccharide c Binding , 2013, mBio.

[9]  A. Lipovsky,et al.  Genome-wide siRNA screen identifies the retromer as a cellular entry factor for human papillomavirus , 2013, Proceedings of the National Academy of Sciences.

[10]  L. Johannes,et al.  N-methyldihydroquinazolinone derivatives of Retro-2 with enhanced efficacy against Shiga toxin. , 2013, Journal of medicinal chemistry.

[11]  J. Decaprio,et al.  A cornucopia of human polyomaviruses , 2013, Nature Reviews Microbiology.

[12]  J. Berger,et al.  Update on Progressive Multifocal Leukoencephalopathy , 2012, Current Neurology and Neuroscience Reports.

[13]  Y. Pang,et al.  Chemical Structure of Retro-2, a Compound That Protects Cells against Ribosome-Inactivating Proteins , 2012, Scientific Reports.

[14]  E. Major,et al.  Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain , 2012, Clinical Microbiology Reviews.

[15]  M. Maginnis,et al.  The VP1 subunit of JC polyomavirus recapitulates early events in viral trafficking and is a novel tool to study polyomavirus entry. , 2012, Virology.

[16]  Meena Subramanyam,et al.  Risk of natalizumab-associated progressive multifocal leukoencephalopathy. , 2012, The New England journal of medicine.

[17]  Hidenobu Suzuki,et al.  The relationship between the plasma concentration of blonanserin, and its plasma anti‐serotonin 5‐HT2A activity/anti‐dopamine D2 activity ratio and drug‐induced extrapyramidal symptoms , 2012, Psychiatry and clinical neurosciences.

[18]  I. Koralnik,et al.  Frequent Infection of Cortical Neurons by JC Virus in Patients With Progressive Multifocal Leukoencephalopathy , 2012, Journal of neuropathology and experimental neurology.

[19]  L. Johannes,et al.  Inhibitors of the Cellular Trafficking of Ricin , 2012, Toxins.

[20]  M. Marsh,et al.  The cell biology of receptor-mediated virus entry , 2011, The Journal of cell biology.

[21]  A. Helenius,et al.  BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol , 2011, Nature Cell Biology.

[22]  Ari Helenius,et al.  Endosome maturation , 2011, The EMBO journal.

[23]  J. Carulli,et al.  Sequencing and Analysis of JC Virus DNA From Natalizumab-Treated PML Patients , 2011, The Journal of infectious diseases.

[24]  J. Carulli,et al.  Progressive multifocal leukoencephalopathy (PML) development is associated with mutations in JC virus capsid protein VP1 that change its receptor specificity. , 2011, The Journal of infectious diseases.

[25]  R. Gold,et al.  Progressive multifocal leukoencephalopathy and natalizumab , 2011, Journal of Neurology.

[26]  J. Ndungu,et al.  Potent Host-Directed Small-Molecule Inhibitors of Myxovirus RNA-Dependent RNA-Polymerases , 2011, PloS one.

[27]  M. Ferrari,et al.  Cellular and molecular biology of glycosphingolipid glycosylation , 2011, Journal of neurochemistry.

[28]  John A. Tallarico,et al.  Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV) , 2011, Proceedings of the National Academy of Sciences.

[29]  A. Helenius,et al.  Role of Endosomes in Simian Virus 40 Entry and Infection , 2011, Journal of Virology.

[30]  R. Maserati,et al.  JC virus VP1 loop-specific polymorphisms are associated with favorable prognosis for progressive multifocal leukoencephalopathy , 2009, Journal of NeuroVirology.

[31]  Billy Tsai,et al.  A PDI Family Network Acts Distinctly and Coordinately with ERp29 To Facilitate Polyomavirus Infection , 2010, Journal of Virology.

[32]  D. Clifford,et al.  Progressive multifocal leukoencephalopathy and other forms of JC virus disease , 2010, Nature Reviews Neurology.

[33]  A. Helenius,et al.  Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation , 2010, The Journal of cell biology.

[34]  T. Stehle,et al.  Structure-function analysis of the human JC polyomavirus establishes the LSTc pentasaccharide as a functional receptor motif. , 2010, Cell host & microbe.

[35]  Mengding Qian,et al.  Lipids and Proteins Act in Opposing Manners To Regulate Polyomavirus Infection , 2010, Journal of Virology.

[36]  M. Maginnis,et al.  Role of N-Linked Glycosylation of the 5-HT2A Receptor in JC Virus Infection , 2010, Journal of Virology.

[37]  V. Nerurkar,et al.  Human polyomavirus JC (JCV) infection of human B lymphocytes: a possible mechanism for JCV transmigration across the blood-brain barrier. , 2010, The Journal of infectious diseases.

[38]  L. Johannes,et al.  Inhibition of Retrograde Transport Protects Mice from Lethal Ricin Challenge , 2010, Cell.

[39]  Petra Schwille,et al.  GM1 structure determines SV40-induced membrane invagination and infection , 2010, Nature Cell Biology.

[40]  Hans Lassmann,et al.  Oligodendrocytes: biology and pathology , 2009, Acta Neuropathologica.

[41]  D. West,et al.  Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project. , 2009, The Lancet. Oncology.

[42]  H. Stenmark.  Rab GTPases as coordinators of vesicle traffic , 2009, Nature Reviews Molecular Cell Biology.

[43]  Dawen Cai,et al.  A Lipid Receptor Sorts Polyomavirus from the Endolysosome to the Endoplasmic Reticulum to Cause Infection , 2009, PLoS pathogens.

[44]  Dong Xu,et al.  Distinct glycan topology for avian and human sialopentasaccharide receptor analogues upon binding different hemagglutinins: a molecular dynamics perspective. , 2009, Journal of molecular biology.

[45]  Adrian Egli,et al.  Prevalence of polyomavirus BK and JC infection and replication in 400 healthy blood donors. , 2009, The Journal of infectious diseases.

[46]  S. Sunyaev,et al.  Adaptive Mutations in the JC Virus Protein Capsid Are Associated with Progressive Multifocal Leukoencephalopathy (PML) , 2009, PLoS genetics.

[47]  T. Stehle,et al.  The Polyomaviridae: Contributions of virus structure to our understanding of virus receptors and infectious entry , 2009, Virology.

[48]  S. Kesari,et al.  Frequent Infection of Cerebellar Granule Cell Neurons by Polyomavirus JC in Progressive Multifocal Leukoencephalopathy , 2009, Journal of neuropathology and experimental neurology.

[49]  B. Thiers,et al.  Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma , 2009 .

[50]  Y. Homma,et al.  Transcriptional control region rearrangements associated with the evolution of JC polyomavirus. , 2008, Virology.

[51]  R. Kast,et al.  Sialic acid moieties and 5-HT2a: two faces of the same receptor for JC virus? , 2008, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

[52]  B. O'Hara,et al.  Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cells Express the Serotonin Receptor and Are Susceptible to JC Virus Infection , 2008, Journal of Virology.

[53]  S. Barnett,et al.  Astrocytes, but not olfactory ensheathing cells or Schwann cells, promote myelination of CNS axons in vitro , 2008, Glia.

[54]  Thilo Stehle,et al.  Structural basis of GM1 ganglioside recognition by simian virus 40 , 2008, Proceedings of the National Academy of Sciences.

[55]  B. O'Hara,et al.  Interferon beta1-a and selective anti-5HT(2a) receptor antagonists inhibit infection of human glial cells by JC virus. , 2008, Virus research.

[56]  W. Atwood,et al.  Direct Correlation between Sialic Acid Binding and Infection of Cells by Two Human Polyomaviruses (JC Virus and BK Virus) , 2007, Journal of Virology.

[57]  Mario Schelhaas,et al.  Simian Virus 40 Depends on ER Protein Folding and Quality Control Factors for Entry into Host Cells , 2007, Cell.

[58]  Anne Imberty,et al.  N-Glycolyl GM1 Ganglioside as a Receptor for Simian Virus 40 , 2007, Journal of Virology.

[59]  V. Nerurkar,et al.  Polyomavirus JC infects human brain microvascular endothelial cells independent of serotonin receptor 2A. , 2007, Virology.

[60]  Anne Imberty,et al.  N-Glycolyl GM 1 Ganglioside as a Receptor for Simian Virus 40 † , 2007 .

[61]  D. Hebert,et al.  SV40 VP2 and VP3 insertion into ER membranes is controlled by the capsid protein VP1: implications for DNA translocation out of the ER. , 2006, Molecular cell.

[62]  W. Atwood,et al.  JC Virus Minor Capsid Proteins Vp2 and Vp3 Are Essential for Virus Propagation , 2006, Journal of Virology.

[63]  B. O'Hara,et al.  Invasion of Host Cells by JC Virus Identifies a Novel Role for Caveolae in EndosomalSorting of Noncaveolar Ligands , 2006, Journal of Virology.

[64]  T. Mikkelsen,et al.  System-wide Genomic and Biochemical Comparisons of Sialic Acid Biology Among Primates and Rodents , 2006, Journal of Biological Chemistry.

[65]  J. Gilbert,et al.  Downregulation of Protein Disulfide Isomerase Inhibits Infection by the Mouse Polyomavirus , 2006, Journal of Virology.

[66]  Philippe Marin,et al.  Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation , 2006, Cell and Tissue Research.

[67]  J. Forstová,et al.  Mouse Polyomavirus Enters Early Endosomes, Requires Their Acidic pH for Productive Infection, and Meets Transferrin Cargo in Rab11-Positive Endosomes , 2006, Journal of Virology.

[68]  E. Peles,et al.  A New Player in CNS Myelination , 2006, Neuron.

[69]  W. Atwood,et al.  The role of sialic acid in human polyomavirus infections , 2006, Glycoconjugate Journal.

[70]  M. Baryshev,et al.  ERp29 triggers a conformational change in polyomavirus to stimulate membrane binding. , 2005, Molecular cell.

[71]  W. Hall,et al.  New sequence polymorphisms in the outer loops of the JC polyomavirus major capsid protein (VP1) possibly associated with progressive multifocal leukoencephalopathy. , 2005, The Journal of general virology.

[72]  W. Lencer,et al.  Ganglioside GD1a Restores Infectibility to Mouse Cells Lacking Functional Receptors for Polyomavirus , 2005, Journal of Virology.

[73]  L. Pelkmans,et al.  Clathrin- and caveolin-1–independent endocytosis: entry of simian virus 40 into cells devoid of caveolae , 2005 .

[74]  L. Schang,et al.  Antiviral drugs that target cellular proteins may play major roles in combating HIV resistance. , 2004, Current pharmaceutical design.

[75]  B. Roth,et al.  The Human Polyomavirus, JCV, Uses Serotonin Receptors to Infect Cells , 2004, Science.

[76]  W. Atwood,et al.  Modeling a Sialic Acid Binding Pocket in the External Loops of JC Virus VP1* , 2004, Journal of Biological Chemistry.

[77]  D. Steindler,et al.  GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis. , 2004, Molecular cell.

[78]  E. Stopa,et al.  Differential distribution of the JC virus receptor-type sialic acid in normal human tissues. , 2004, The American journal of pathology.

[79]  P. P. Di Fiore,et al.  A JC Virus-Induced Signal Is Required for Infection of Glial Cells by a Clathrin- and eps15-Dependent Pathway , 2004, Journal of Virology.

[80]  G. Tettamanti.  Ganglioside/glycosphingolipid turnover: New concepts , 2003, Glycoconjugate Journal.

[81]  L. J. Rubinstein,et al.  Electron microscopic observations on a case of progressive multifocal leukoencephalopathy , 1965, Acta Neuropathologica.

[82]  C. Rodighiero,et al.  Gangliosides that associate with lipid rafts mediate transport of cholera and related toxins from the plasma membrane to endoplasmic reticulm. , 2003, Molecular biology of the cell.

[83]  U. de Girolami,et al.  Productive infection of cerebellar granule cell neurons by JC virus in an HIV+ individual , 2003, Neurology.

[84]  Thilo Stehle,et al.  Gangliosides are receptors for murine polyoma virus and SV40 , 2003, The EMBO journal.

[85]  J. Forstová,et al.  Mouse Polyomavirus Utilizes Recycling Endosomes for a Traffic Pathway Independent of COPI Vesicle Transport , 2003, Journal of Virology.

[86]  W. Atwood,et al.  Oligosaccharides as Receptors for JC Virus , 2002, Journal of Virology.

[87]  W. Atwood,et al.  Construction of a novel JCV/SV40 hybrid virus (JCSV) reveals a role for the JCV capsid in viral tropism. , 2002, Virology.

[88]  Lucas Pelkmans,et al.  Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER , 2001, Nature Cell Biology.

[89]  Marino Zerial,et al.  Rab proteins as membrane organizers , 2001, Nature Reviews Molecular Cell Biology.

[90]  B. Schweighardt,et al.  Glial cells as targets of viral infection in the human central nervous system. , 2001, Progress in brain research.

[91]  W. Atwood,et al.  JC virus binds to primary human glial cells, tonsillar stromal cells, and B-lymphocytes, but not to T lymphocytes. , 2000, Journal of neurovirology.

[92]  W. Atwood,et al.  JC Virus Enters Human Glial Cells by Clathrin-Dependent Receptor-Mediated Endocytosis , 2000, Journal of Virology.

[93]  Carolyn R. Bertozzi,et al.  Essentials of Glycobiology , 1999 .

[94]  S. Harrison,et al.  Interaction of polyomavirus internal protein VP2 with the major capsid protein VP1 and implications for participation of VP2 in viral entry , 1998, The EMBO journal.

[95]  W. Atwood,et al.  Infection of Glial Cells by the Human Polyomavirus JC Is Mediated by an N-Linked Glycoprotein Containing Terminal α(2-6)-Linked Sialic Acids , 1998, Journal of Virology.

[96]  W. Atwood,et al.  The human polyomavirus, JCV, does not share receptor specificity with SV40 on human glial cells. , 1998, Journal of neurovirology.

[97]  K. Dörries.  Molecular biology and pathogenesis of human polyomavirus infections. , 1998, Developments in biological standardization.

[98]  D. Lanska,et al.  Progressive multifocal leukoencephalopathy in patients with HIV infection. , 1998, Journal of neurovirology.

[99]  A. Ferrer,et al.  Latency and reactivation of JC virus in peripheral blood of human immunodeficiency virus type 1-infected patients , 1997, Journal of clinical microbiology.

[100]  A. Deutch,et al.  Serotonin 5‐HT2A receptors are expressed on pyramidal cells and interneurons in the rat cortex , 1997, Synapse.

[101]  B. Norrild,et al.  Fundamental virology, 3rd edn. , 1996 .

[102]  J. Ragnaud,et al.  Detection of JC virus DNA in the peripheral blood leukocytes of HIV‐infected patients , 1996, AIDS.

[103]  M. Wegner,et al.  Functional comparison of PML-type and archetype strains of JC virus , 1996, Journal of virology.

[104]  K. Khalili,et al.  Sequences within the early and late promoters of archetype JC virus restrict viral DNA replication and infectivity. , 1996, Virology.

[105]  C. Ryschkewitsch,et al.  Genotype profile of human polyomavirus JC excreted in urine of immunocompetent individuals , 1996, Journal of clinical microbiology.

[106]  E. sanders-Bush,et al.  Identification of rat serotonin 5-HT2C receptors as glycoproteins containing N-linked oligosaccharides. , 1995, Brain research. Molecular brain research.

[107]  R. Eglen,et al.  The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors , 1995, British journal of pharmacology.

[108]  C. Krebs,et al.  The JC virus minimal core promoter is glial cell specific in vivo , 1995, Journal of virology.

[109]  S. Günther,et al.  Infection of human polyomaviruses JC and BK in peripheral blood leukocytes from immunocompetent individuals. , 1994, Virology.

[110]  E. Major,et al.  Interaction of the human polyomavirus, JCV, with human B-lymphocytes. , 1992, Virology.

[111]  E. Major,et al.  Detection of JC virus DNA in peripheral lymphocytes from patients with and without progressive multifocal leukoencephalopathy , 1992, Annals of neurology.

[112]  L. Riboni,et al.  Rapid Internalization and Intracellular Metabolic Processing of Exogenous Ganglioside by Cerebellar Granule Cells Differentiated in Culture , 1991, Journal of neurochemistry.

[113]  R. Liddington,et al.  Structure of simian virus 40 at 3.8-Å resolution , 1991, Nature.

[114]  S. Wong,et al.  Inhibition by brefeldin A of protein secretion from the apical cell surface of Madin-Darby canine kidney cells. , 1991, The Journal of biological chemistry.

[115]  R. Garcea,et al.  A single-amino-acid substitution in polyomavirus VP1 correlates with plaque size and hemagglutination behavior , 1991, Journal of virology.

[116]  T. Kitamura,et al.  Isolation of a possible archetypal JC virus DNA sequence from nonimmunocompromised individuals , 1990, Journal of virology.

[117]  J. Lippincott-Schwartz,et al.  Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER , 1989, Cell.

[118]  J F Vliegenthart,et al.  Conformational analysis of the sialyl alpha(2----3/6)N-acetyllactosamine structural element occurring in glycoproteins, by two-dimensional NOE 1H-NMR spectroscopy in combination with energy calculations by hard-sphere exo-anomeric and molecular mechanics force-field with hydrogen-bonding potential. , 1989, European journal of biochemistry.

[119]  C. Kufta,et al.  Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy. , 1988, The New England journal of medicine.

[120]  Y. Misumi,et al.  Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes. , 1986, The Journal of biological chemistry.

[121]  S. Kenney,et al.  Mapping 5' termini of JC virus early RNAs , 1986, Journal of virology.

[122]  S. Kenney,et al.  Mapping 5' termini of JC virus late RNA , 1986, Journal of virology.

[123]  R. Frisque,et al.  Differences in regulatory sequences of naturally occurring JC virus variants , 1985, Journal of virology.

[124]  R. Frisque,et al.  Human polyomavirus JC virus genome , 1984, Journal of virology.

[125]  R. Frisque.  Nucleotide sequence of the region encompassing the JC virus origin of DNA replication , 1983, Journal of virology.

[126]  R. Frisque.  Regulatory sequences and virus-cell interactions of JC virus. , 1983, Progress in clinical and biological research.

[127]  G. Z. Zu Rhein,et al.  Particles Resembling Papova Viruses in Human Cerebral Demyelinating Disease , 1965, Science.

[128]  E. Mancall,et al.  Progressive multifocal leuko-encephalopathy; a hitherto unrecognized complication of chronic lymphatic leukaemia and Hodgkin's disease. , 1958, Brain : a journal of neurology.

[129]  G. Blix,et al.  Sialic Acids , 1955, Nature.