Crystal structure of the human σ1 receptor
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[1] Deo R. Singh,et al. The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands. , 2015, The Biochemical journal.
[2] T. Mavlyutov,et al. Role of the Sigma-1 receptor in Amyotrophic Lateral Sclerosis (ALS) , 2015, Journal of pharmacological sciences.
[3] K. Fukunaga,et al. Methyl pyruvate rescues mitochondrial damage caused by SIGMAR1 mutation related to amyotrophic lateral sclerosis. , 2014, Biochimica et biophysica acta.
[4] Dennis K. Miller,et al. Relationship between Cerebral Sigma-1 Receptor Occupancy and Attenuation of Cocaine’s Motor Stimulatory Effects in Mice by PD144418 , 2014, The Journal of Pharmacology and Experimental Therapeutics.
[5] B. Fox,et al. The Oligomeric States of the Purified Sigma-1 Receptor Are Stabilized by Ligands , 2014, The Journal of Biological Chemistry.
[6] Piotr Sliz,et al. Collaboration gets the most out of software , 2013, eLife.
[7] T. Mavlyutov,et al. Lack of sigma-1 receptor exacerbates ALS progression in mice , 2013, Neuroscience.
[8] P. Zwart,et al. Towards automated crystallographic structure refinement with phenix.refine , 2012, Acta crystallographica. Section D, Biological crystallography.
[9] F. Al-Mohanna,et al. A mutation in sigma‐1 receptor causes juvenile amyotrophic lateral sclerosis , 2011, Annals of neurology.
[10] Hyeon Joo,et al. OPM database and PPM web server: resources for positioning of proteins in membranes , 2011, Nucleic Acids Res..
[11] S. Buch,et al. The sigma-1 receptor chaperone as an inter-organelle signaling modulator. , 2010, Trends in pharmacological sciences.
[12] S. Rasmussen,et al. Structure of a nanobody-stabilized active state of the β2 adrenoceptor , 2010, Nature.
[13] Tal Pupko,et al. ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids , 2010, Nucleic Acids Res..
[14] Liisa Holm,et al. Dali server: conservation mapping in 3D , 2010, Nucleic Acids Res..
[15] G. Pasternak,et al. σ1 Receptor Modulation of G-Protein-Coupled Receptor Signaling: Potentiation of Opioid Transduction Independent from Receptor Binding , 2010, Molecular Pharmacology.
[16] Vincent B. Chen,et al. MolProbity: all-atom structure validation for macromolecular crystallography , 2009, Acta crystallographica. Section D, Biological crystallography.
[17] Tangui Maurice,et al. The pharmacology of sigma-1 receptors. , 2009, Pharmacology & therapeutics.
[18] J. Entrena,et al. Pharmacology and Therapeutic Potential of Sigma1 Receptor Ligands , 2008, Current neuropharmacology.
[19] W. Bowen,et al. Role of Sigma-1 Receptor C-terminal Segment in Inositol 1,4,5-Trisphosphate Receptor Activation , 2008, Journal of Biological Chemistry.
[20] Teruo Hayashi,et al. Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival , 2007, Cell.
[21] Seung Woo Shin,et al. Dextromethorphan attenuates trimethyltin-induced neurotoxicity via σ1 receptor activation in rats , 2007, Neurochemistry International.
[22] V. Reisinger,et al. Analysis of Membrane Protein Complexes by Blue Native PAGE , 2006, Proteomics.
[23] Axel T Brunger,et al. Refractive index‐based determination of detergent concentration and its application to the study of membrane proteins , 2005, Protein science : a publication of the Protein Society.
[24] G. Debonnel,et al. Distinct modulatory roles of sigma receptor subtypes on glutamatergic responses in the dorsal hippocampus , 2005, Synapse.
[25] Conrad C. Huang,et al. UCSF Chimera—A visualization system for exploratory research and analysis , 2004, J. Comput. Chem..
[26] J. Cedarbaum. Survival , 2004 .
[27] G Bricogne,et al. Generation, representation and flow of phase information in structure determination: recent developments in and around SHARP 2.0. , 2003, Acta crystallographica. Section D, Biological crystallography.
[28] Meyer B. Jackson,et al. The Sigma Receptor as a Ligand-Regulated Auxiliary Potassium Channel Subunit , 2002, Neuron.
[29] G. Pasternak,et al. Sigma1 receptor modulation of opioid analgesia in the mouse. , 2002, The Journal of pharmacology and experimental therapeutics.
[30] P. Casellas,et al. Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor. , 2001, Biochimica et biophysica acta.
[31] B. Roth,et al. The Multiplicity of Serotonin Receptors: Uselessly Diverse Molecules or an Embarrassment of Riches? , 2000 .
[32] P. Casellas,et al. Colocalization of sterol isomerase and sigma(1) receptor at endoplasmic reticulum and nuclear envelope level. , 1999, European journal of biochemistry.
[33] S. Okuyama,et al. Amino acid residues in the transmembrane domain of the type 1 sigma receptor critical for ligand binding , 1999, FEBS letters.
[34] K. Kovács,et al. Up-regulation of [3H]DTG but not [3H](+)-pentazocine labeled sigma sites in mouse spinal cord by chronic morphine treatment. , 1998, European journal of pharmacology.
[35] T. Heffner,et al. The Pharmacology of the Novel and Selective Sigma Ligand, PD 144418 , 1997, Neuropharmacology.
[36] E. Kempner,et al. Purification, molecular cloning, and expression of the mammalian sigma1-binding site. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[37] W. Bowen,et al. Synthesis and characterization of [125I]-N-(N-benzylpiperidin-4-yl)-4- iodobenzamide, a new sigma receptor radiopharmaceutical: high-affinity binding to MCF-7 breast tumor cells. , 1994, Journal of medicinal chemistry.
[38] M. Brownstein. A brief history of opiates, opioid peptides, and opioid receptors. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[39] S. Snyder,et al. Structural determinants of sigma receptor affinity. , 1987, Molecular pharmacology.
[40] J. Thompson,et al. The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog. , 1976, The Journal of pharmacology and experimental therapeutics.
[41] B. Lucke-Wold,et al. Role of sigma-1 receptors in neurodegenerative diseases. , 2015, Journal of pharmacological sciences.
[42] V. Cherezov,et al. Crystallizing membrane proteins using lipidic mesophases , 2009, Nature Protocols.
[43] Teruo Hayashi,et al. Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival. , 2007, Cell.
[44] W. Delano. The PyMOL Molecular Graphics System , 2002 .