Structural and functional investigations of the murine cavernosal nerve: a model system for serial spatio‐temporal study of autonomic neuropathy

To illustrate the ultrastructural fibre composition of the rat cavernosal nerve at serial levels, from its origin in the main pelvic ganglion to its termination in the corpus cavernosum of the distal penile shaft, and to develop a technique that permits repeated electrophysiological recording from the fibres that form the cavernosal nerve distinct from the axons of the dorsal nerve of the penis (DNP).

[1]  Weixin Zhao,et al.  Intracorporal injection of hSlo cDNA restores erectile capacity in STZ-diabetic F-344 rats in vivo. , 2004, American journal of physiology. Heart and circulatory physiology.

[2]  R. Schmidt,et al.  Experimental Rat Models of Types 1 and 2 Diabetes Differ in Sympathetic Neuroaxonal Dystrophy , 2004, Journal of neuropathology and experimental neurology.

[3]  S. Moncada,et al.  Two phases of nitrergic neuropathy in streptozotocin-induced diabetic rats. , 2003, Diabetes.

[4]  R. Costabile.  Optimizing treatment for diabetes mellitus induced erectile dysfunction. , 2003, The Journal of urology.

[5]  L. Baskin,et al.  Identification of communicating branches among the dorsal, perineal and cavernous nerves of the penis. , 2003, The Journal of urology.

[6]  J. Arezzo,et al.  The neuropathy of erectile dysfunction , 2002, International Journal of Impotence Research.

[7]  R. Schmidt.  Neuronal preservation in the sympathetic ganglia of rats with chronic streptozotocin-induced diabetes , 2001, Brain Research.

[8]  A. Abramovici,et al.  Effects of senescence and citral on neuronal vacuolar degeneration in rat pelvic ganglia. , 2001, Neurotoxicology.

[9]  K. McVary,et al.  Protein and gene expression of nitric oxide synthase isoforms I and III in the rat penile shaft , 2002, International Journal of Impotence Research.

[10]  W. Steers.  Neural pathways and central sites involved in penile erection: neuroanatomy and clinical implications , 2000, Neuroscience & Biobehavioral Reviews.

[11]  G. Christ,et al.  Analysis of the presence and physiological relevance of subconducting states of Connexin43-derived gap junction channels in cultured human corporal vascular smooth muscle cells. , 1999, Circulation research.

[12]  H. Sürücü,et al.  Histopathological changes and nitric oxide synthase activity in corpus cavernosum from rats with neurogenic erectile dysfunction , 1999, BJU international.

[13]  D. Guidolin,et al.  Ultrastructural analysis of the cavernous and dorsal penile nerves in experimental diabetes. , 1993, International journal of impotence research.

[14]  E. Hertzberg,et al.  Gap junctions formed of connexin43 are found between smooth muscle cells of human corpus cavernosum. , 1993, The Journal of urology.

[15]  J. Mcleod,et al.  Autonomic Dysfunction in Peripheral Nerve Disease , 1993, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[16]  G. Walton,et al.  The vasculature of the rat penis: a scanning electron microscopic and histologic study. , 1991, The American journal of anatomy.

[17]  B D Sachs,et al.  The ischiourethralis muscle of the rat: Anatomy, innervation, and function , 1991, The Anatomical record.

[18]  C. Jf,et al.  [Diabetic autonomic neuropathy]. , 1989, Atencion primaria.

[19]  G. Walton,et al.  Autonomic innervation of reproductive organs: Analysis of the neurons whose axons project in the main penile nerve in the pelvic plexus of the rat , 1989, The Anatomical record.

[20]  W. D. de Groat,et al.  Electrophysiological study of neural activity in penile nerve of the rat. , 1988, The American journal of physiology.

[21]  S. Yagihashi,et al.  Neuroaxonal and Dendritic Dystrophy in Diabetic Autonomic Neuropathy. Classification and Topographic Distribution in the BB‐Rat , 1986, Journal of neuropathology and experimental neurology.

[22]  R. Schmidt,et al.  Ultrastructural and Biochemical Characterization of Autonomic Neuropathy in Rats with Chronic Streptozotocin Diabetes , 1986, Journal of neuropathology and experimental neurology.

[23]  S. Yagihashi,et al.  Diabetic Autonomic Neuropathy in BB Rat: Ultrastructural and Morphometric Changes in Parasympathetic Nerves , 1986, Diabetes.

[24]  I. Nadelhaft,et al.  The organization of the pudendal nerve in the male and female rat , 1986, The Journal of comparative neurology.

[25]  U. Junker,et al.  Varied effects of experimental diabetes on the autonomic nervous system of the rat. , 1986, Laboratory investigation; a journal of technical methods and pathology.

[26]  S. Yagihashi,et al.  Diabetic Autonomic Neuropathy in the BB rat: Ultrastructural and Morphometric Changes in Sympathetic Nerves , 1985, Diabetes.

[27]  B. Ding,et al.  Ultrastructural studies on the , 1983 .

[28]  R. Coggeshall,et al.  An analysis of the axon populations in the nerves to the pelvic viscera in the rat , 1982, The Journal of comparative neurology.

[29]  H. Vaughan,et al.  Averaged multiple unit activity as an estimate of phasic changes in local neuronal activity: effects of volume-conducted potentials , 1980, Journal of Neuroscience Methods.

[30]  H. Hervonen,et al.  Vacuolated neurons in the hypogastric ganglion of the rat , 1979, Cell and Tissue Research.

[31]  P. Spencer,et al.  Distal axonopathy: one common type of neurotoxic lesion. , 1978, Environmental health perspectives.

[32]  T. Fletcher,et al.  Innervation of pelvic viscera in the rat. Evoked potentials in nerves to bladder and penis (clitoris). , 1976, Investigative urology.

[33]  H. Wiśniewski,et al.  ULTRASTRUCTURAL STUDIES OF THE DYING‐BACK PROCESS: 1. PERIPHERAL NERVE TERMINAL AND AXON DEGENERATION IS SYSTEMIC ACRYLAMIDE INTOXICATION , 1974, Journal of neuropathology and experimental neurology.

[34]  T. Fletcher,et al.  Gross and light microscopic features of the pelvic plexus in the rat , 1973, The Anatomical record.

[35]  T. S. Leeson,et al.  The fine structure of cavernous tissue in the adult rat penis. , 1965, Investigative urology.

[36]  Langworthy Or.  INNERVATION OF THE PELVIC ORGANS OF THE RAT. , 1965 .

[37]  R. Schmidt.  Neuropathology and pathogenesis of diabetic autonomic neuropathy. , 2002, International review of neurobiology.

[38]  K. McVary,et al.  Sexual dysfunction in the diabetic BB/WOR rat: a role of central neuropathy. , 1997, The American journal of physiology.

[39]  W. G. Dail.  The pelvic plexus: innervation of pelvic and extrapelvic visceral tissues. , 1996, Microscopy research and technique.

[40]  J. Gärtner,et al.  Experimental autonomic neuropathy in the choroid of streptozotocin-diabetic rats. Electron microscopic observations. , 1989, Retina.

[41]  P. Spencer,et al.  Pyridoxine megavitaminosis produces degeneration of peripheral sensory neurons (sensory neuronopathy) in the dog. , 1981, Neurotoxicology.

[42]  O. R. Langworthy.  INNERVATION OF THE PELVIC ORGANS OF THE RAT. , 1965, Investigative urology.