Robustness and enhancement of neural synchronization by activity-dependent coupling.

We study the synchronization of two model neurons coupled through a synapse having an activity-dependent strength. Our synapse follows the rules of spike-timing dependent plasticity. We show that this plasticity of the coupling between neurons produces enlarged frequency-locking zones and results in synchronization that is more rapid and much more robust against noise than classical synchronization arising from connections with constant strength. We also present a simple discrete map model that demonstrates the generality of the phenomenon.

[1]  R. Traub,et al.  Neuronal Networks of the Hippocampus , 1991 .

[2]  L. Glass.  Synchronization and rhythmic processes in physiology , 2001, Nature.

[3]  Christoph Braun,et al.  Coherence of gamma-band EEG activity as a basis for associative learning , 1999, Nature.

[4]  G. Bi,et al.  Synaptic Modifications in Cultured Hippocampal Neurons: Dependence on Spike Timing, Synaptic Strength, and Postsynaptic Cell Type , 1998, The Journal of Neuroscience.

[5]  Elmer S. West.  From the U. S. A. , 1965 .

[6]  E. Capaldi,et al.  The organization of behavior. , 1992, Journal of applied behavior analysis.

[7]  C. Elger,et al.  Human memory formation is accompanied by rhinal–hippocampal coupling and decoupling , 2001, Nature Neuroscience.

[8]  P. Bressloff,et al.  Mode locking and Arnold tongues in integrate-and-fire neural oscillators. , 1999, Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics.

[9]  A. Selverston,et al.  Synchronous Behavior of Two Coupled Biological Neurons , 1998, chao-dyn/9811010.

[10]  A. I.,et al.  Neural Field Continuum Limits and the Structure–Function Partitioning of Cognitive–Emotional Brain Networks , 2023, Biology.

[11]  R Huerta,et al.  Dynamical encoding by networks of competing neuron groups: winnerless competition. , 2001, Physical review letters.

[12]  Ramón Huerta,et al.  Dynamical encoding by networks of competing neuron groups: winnerless competition. , 2001 .

[13]  H. Markram,et al.  Regulation of Synaptic Efficacy by Coincidence of Postsynaptic APs and EPSPs , 1997, Science.

[14]  A. Winfree.  The geometry of biological time , 1991 .

[15]  V. Han,et al.  Synaptic plasticity in the mormyrid electrosensory lobe. , 1999, The Journal of experimental biology.

[16]  G. Laurent.  A systems perspective on early olfactory coding. , 1999, Science.

[17]  J. Lacaille,et al.  A hebbian form of long-term potentiation dependent on mGluR1a in hippocampal inhibitory interneurons , 2001, Proceedings of the National Academy of Sciences of the United States of America.