Isolation and structure characterization of related impurities in Sodium Tanshinone IIA Sulfonate by LC/ESI-MS(n) and NMR.

[1]  X. Tan,et al.  Unique action of sodium tanshinone II-A sulfonate (DS-201) on the Ca(2+) dependent BK(Ca) activation in mouse cerebral arterial smooth muscle cells. , 2011, European journal of pharmacology.

[2]  Wei-chuan Yang,et al.  Effects of sodium tanshinone II A sulphonate on hypoxic pulmonary hypertension in rats in vivo and on Kv2.1 expression in pulmonary artery smooth muscle cells in vitro. , 2009, Journal of ethnopharmacology.

[3]  P. Wei,et al.  Identification, Isolation, and Characterization of Impurities in Sodium Tanshinone IIA Sulfonate , 2009 .

[4]  Miaoling Li,et al.  Activation of high conductance Ca(2+)-activated K(+) channels by sodium tanshinoneII-A sulfonate (DS-201) in porcine coronary artery smooth muscle cells. , 2008, European journal of pharmacology.

[5]  Guangji Wang,et al.  Determination of sodium tanshinone IIA sulfonate in plasma by liquid chromatography-electrospray ionisation-tandem mass spectrometry. , 2007, Biomedical chromatography : BMC.

[6]  Xiaochi Ma,et al.  Profiling the metabolic difference of seven tanshinones using high-performance liquid chromatography/multi-stage mass spectrometry with data-dependent acquisition. , 2007, Rapid communications in mass spectrometry : RCM.

[7]  Shixiang Hou,et al.  Ion-pair reversed-phase HPLC method for determination of sodium tanshinone IIA sulfonate in biological samples and its pharmacokinetics and biodistribution in mice. , 2007, Chemical & pharmaceutical bulletin.

[8]  Y. Bi,et al.  Ion-pair reversed-phase HPLC: assay validation of sodium tanshinone IIA sulfonate in mouse plasma. , 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[9]  W. Xin,et al.  Sodium tanshinone IIA sulfonate mediates electron transfer reaction in rat heart mitochondria. , 2003, Biochemical pharmacology.

[10]  K. Fung,et al.  Effect of sodium tanshinone IIA sulfonate in the rabbit myocardium and on human cardiomyocytes and vascular endothelial cells. , 1993, Biochemical pharmacology.